A5066449253- Reproductive System and Pregnancy
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Endometriosis Research and Treatment
- Renal and related cancers
- Reproductive Health and Technologies
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Sperm and Testicular Function
- Ovarian cancer diagnosis and treatment
- Endometrial and Cervical Cancer Treatments
- Immune Cell Function and Interaction
- Single-cell and spatial transcriptomics
- Electrospun Nanofibers in Biomedical Applications
- Prenatal Screening and Diagnostics
- Chronic Kidney Disease and Diabetes
- Maternal and fetal healthcare
- TGF-β signaling in diseases
- Epigenetics and DNA Methylation
- Circular RNAs in diseases
- Cancer-related molecular mechanisms research
- Cardiovascular Health and Disease Prevention
- Cardiovascular Disease and Adiposity
- Systemic Lupus Erythematosus Research
- Osteoarthritis Treatment and Mechanisms
Sichuan University
2009-2024
West China Second University Hospital of Sichuan University
2007-2024
Duke University
2021
West China Hospital of Sichuan University
2011
// Zhongying Huang 1 , Shangwei Li Wei Fan Qianhong Ma Department of Obsterics and Gynecology, West China 2nd Hospital, University Sichuan, Key Laboratory Birth Defects Related Diseases Women Children, Ministry Education, Chengdu 610041, People's Republic Correspondence to: Huang, email: huangzyhxyd@scu.edu.cn Fan, fw215@163.com Keywords: TGF-β signaling, Smads, matrix metalloproteinases, trophoblast Received: September 24, 2016 Accepted: March 26, 2017 Published: April 04, ABSTRACT...
Abstract Background Unexplained recurrent spontaneous abortion (URSA) is defined as two or more consecutive pregnancy losses, generally of unknown cause; it related to a failure fetal–maternal immunological tolerance. Regulatory T cells (Tregs) exert immunosuppressive effects, which are essential maintain tolerance and regulate immune balance. In this study, we used the specific cell-surface phenotype CD4 + CD25 high CD127 low/− Tregs investigate number suppressive function isolated from...
BACKGROUND: Ovarian tissue cryopreservation for fertility preservation carries a risk of malignant cell re-seeding. Artificial ovary is promising method to solve such problem. However, decellularization protocols are limited. Hence, further studies necessary get better ovarian techniques the construction artificial scaffolds. OBJECTIVE: To establish an innovative technique whole porcine ovaries by integrating liquid nitrogen with chemical agents reduce contact time between scaffolds and...
Abstract: Lynch syndrome (LS) is an autosomal dominant hereditary tumor characterized by tumors in the uterus and ovaries of female patients. Atypical endometrial hyperplasia (AH) or carcinoma (EC) LS patients caused germline mutations. Few studies have analyzed role estrogen fertility-sparing therapies for these Here we reported a patient who had AH attempted to preserve her fertility under close monitoring after multidisciplinary consultations. The lesion was completely reversed 3 months...
Objective To compare the discursion of endothelial function and metabolism in obese isolated impaired fasting glucose (I-IFG ) tolerance(I-IGT). Methods Sixty cases I-IFG(group C including obesity(group C2;32 cases) no-obesity (group C1;28cases) 83 I-IGT(group D D2;42 D1:41cases) were compared to 142 normal tolerance N N2;67 N1;75 cases). All detected insulin with oral test release test. Fasting venous blood all samples obtained measure levels lipids, free fatty acids(FFA),...
Objectives: Focal Segmental Glomerulosclerosis (FSGS) is a progressive glomerular disease.The pathogenesis of this disease, however, remains unclear.Here, we attempted to identify key candidate genes in FSGS through stringent bioinformatic analysis. Methods:We systematically searched the Gene Expression Omnibus database for gene expression microarrays derived from human glomeruli tissues with FSGS.First, identified differentially expressed (DEGs) by using Limma package R.Then, subjected...
Background: This study aims to compare the effect of tamoxifen (TMX) vs. other regimens on endometrial thickness (EMT), clinical pregnancy, implantation, miscarriage, and live birth rates in women with thin endometrium undergoing frozen-thawed embryo transfer (FET). Methods: We searched Cochrane Central Register Controlled Trials, MEDLINE, EMBASE, CINAHL from inception November 2020 cross-checked references relevant articles. included randomized controlled trials (RCTs) nonrandomized...