A5102942633- Hormonal and reproductive studies
- Sexual function and dysfunction studies
- Urinary Bladder and Prostate Research
- Sexual Differentiation and Disorders
- Prostate Cancer Diagnosis and Treatment
- Hypothalamic control of reproductive hormones
- Antibiotic Resistance in Bacteria
- Stress Responses and Cortisol
- Pharmacology and Obesity Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Ovarian function and disorders
- Apelin-related biomedical research
- Pelvic floor disorders treatments
- Fluorine in Organic Chemistry
- Sexuality, Behavior, and Technology
- Innovative Microfluidic and Catalytic Techniques Innovation
- Healthcare and Venom Research
- Various Chemistry Research Topics
- Acoustic Wave Resonator Technologies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Congenital heart defects research
- Antibiotics Pharmacokinetics and Efficacy
- Vaccine Coverage and Hesitancy
- Reproductive System and Pregnancy
- Immune cells in cancer
Tianjin University
2025
Sichuan University
2022-2025
Zhejiang Normal University
2024
Obstetrics and Gynecology Hospital of Fudan University
2019-2022
Tianjin Medical University General Hospital
2021
Chinese People's Armed Police Force
2020
Pingjin Hospital
2018
Shanghai University of Traditional Chinese Medicine
2017-2018
Shanghai University
2017-2018
Seventh People's Hospital of Shanghai
2017-2018
In a community-based study, the relationship between age and human prostate size was investigated in population of men ages 40 70 years to determine normal increase curve equation.One thousand male volunteers were randomly recruited from Shanghai community, length, width, height, volume transition zone (TZ) whole prostates measured by transrectal ultrasound (TRUS).Each volunteer evaluated International Prostate Symptom Score (IPSS).Among those who completed examination, mean parameters all...
During the coronavirus disease (COVID-19) epidemic, there have been concerns about impact of vaccines on people's fertility, including fertility those who are currently preparing for pregnancy and might become pregnant in future. However, is still a lack research effect COVID-19 vaccine male it not surprising that couples donors regarding vaccination. In this study, retrospective cohort study was conducted to examine semen quality before after receipt inactivated vaccine. There were no...
This study was performed to investigate a potential marker for the presence of spermatozoa in ejaculate following varicocelectomy Chinese men with nonobstructive azoospermia and varicoceles. The micro-RNA (miR)-192a levels seminal plasma testicular tissue were evaluated by quantitative real-time polymerase chain reaction from 60 varicoceles (Group A: 27 found after surgery; Group B: 33 without surgery) 30 controls. miR-192a higher B than A controls (P < 0.001), there no significant...
The sulfonium–Claisen rearrangement of aryl fluoroalkyl sulfoxides with acetonitrile enables the simultaneous incorporation a cyanomethyl group and fluoroalkylthio into arenes.
This study aimed to explore the expression characteristics of miRNAs in cardiovascular diseases (CVD) and depression within a plateau environment, better understand their potential role Plateau Psycho-CVD. A prospective design was employed analyze circulating small RNAs from 20 subjects using high-throughput sequencing technology. Participants were divided into four groups (C, PPC, PP, PC) for comparative analysis. Differentially expressed selected further functional enrichment The findings...
Background: Obesity is becoming increasingly prevalent in modern society, leading to a rise the incidence of obesity hypoventilation syndrome (OHS). This study analyzes factors influencing weight regain OHS patients following laparoscopic sleeve gastrectomy (LSG), based on gastrointestinal peptide hormones. Methods: A total 134 who underwent LSG at our hospital between January 2023 and 2024 were enrolled. The alterations hormones, including insulin (INS), leptin (Lep), glucagon-like...
Abstract Destruction of endothelial cells (ECs) function is involved in the structural and functional pathophysiological processes preeclampsia (PE). Vascular injury may pre‐exist for several years women that develop PE pose increased risks hypertension, coronary artery disease, type‐2 diabetes mellitus. Previous findings showed Elabela (ELA), endogenous ligand apelin (APJ) receptor expressed mainly on ECs, play a protective role early pregnancy prevent PE. However, exact molecular...
Objective: To analyze the impact of age, BMI and sex hormone on aging males' symptoms (AMS) 5-item version international index erectile function (IIEF-5) scores in middle-aged elderly Chinese men.Methods: A population-based cross-sectional study was conducted Jiashan County. total 969 men, aged between 40 80 years old, were admitted. Physical examination hormones measured, AMS IIEF-5 assessed.Results: The oneway ANOVA analysis indicated older age groups had higher total-scores, somatic...
Metallo-β-lactamases (MBLs) are zinc-dependent enzymes capable of hydrolyzing all bicyclic β-lactam antibiotics, posing a great threat to public health. However, there currently no clinically approved MBL inhibitors. Despite variations in their active sites, MBLs share common catalytic mechanism with carbapenems, forming similar reaction species and hydrolysates. We here report the development 2-aminothiazole-4-carboxylic acids (AtCs) as broad-spectrum inhibitors by mimicking anchor...
This study sought to investigate late-onset hypogonadism (LOH) in old and middle-aged males Shanghai communities, using symptom score evaluation systems measurements of sex hormone levels.One thousand cases aged 40-70 years were investigated.The aging male symptoms (AMS) scale androgen deficiency (ADAM) questionnaire used at the beginning investigation, followed by measurement hormone-related factors (total testosterone (TT), free (fT), hormone-binding globulin (SHBG) bioavailability...
The association between hypogonadism symptoms and the levels of serum hormones are still in debate. To investigate relationship middle-aged elderly Chinese men, this community-based cross-sectional study was conducted based on a total 965 ageing men. males' symptom (AMS) scale, International Index Erectile Function-5 (IIEF-5), Prostate Symptom Score (IPSS) questionnaires related variables were assessed. Blood tests for testosterone (TT), sex hormone-binding globulin (SHBG) luteinising...
Medicinal chemistry is an integrated discipline that primarily concerns the design, discovery, synthesis, identification, and interpretation of biologically active compounds at molecular level. To assist undergraduates in understanding core subjects medicinal chemistry, we introduced a closed-loop education mode combining fundamentals theoretical experimental aspects undergraduate course. Since "Antibiotics" chapter important component our lecture course, topic "design, synthesis biological...
Research on the relationship between physical activity and aging symptoms among men is limited in China.Eight hundred nineteen participants aged 40 to 70 (mean age = 58.25) were administered International Physical Activity Questionnaire Aging Males' Symptoms scale (AMS) face-to-face interviews 2009 2010. Ordinal logistic regression generalized linear models used examine severity of symptoms. AMS total score subscale scores (psychological, somatic, sexual health) examined according...
Abstract Objective: To identify the sociodemographic characteristics, motivations, and semen parameters of sperm donors in Shanghai, China. Methods: The participants were associated with Human Sperm Bank Fudan University Among 334 that applied for participation, 329 completed survey process. responses obtained questionnaire face-to-face interviews used to investigate donor motivations quality was examined parameter. Results: In terms an altruistic this study aged between 26 30 years, single,...
Background To investigate whether serum levels of sex hormone-binding globulin (SHBG) and testosterone are associated with symptomatic late-onset hypogonadism (SLOH) in middle-aged elderly rural Chinese males.A population-based cross-sectional study was conducted Zhejiang communities. A total 965 men (aged 40-80 years) were admitted to the aging males' symptoms (AMS) scale related physical examinations including body mass index (BMI) waist circumference conducted. Serum (TT), free (FT),...
The objective of the current study was to explore relationship between longitudinal change in body mass index (BMI) and reproductive hormones middle-aged elderly Chinese men. A cohort conducted a rural area China. Local male residents aged 40–80 years were recruited at baseline 2012 followed up 2016. Information about weight, height, waist circumference, sex hormones, smoking status, medical history obtained. BMI reported no significant with total testosterone (TT), calculated free (cFT),...