A5101777675- Genomics, phytochemicals, and oxidative stress
- CRISPR and Genetic Engineering
- Animal Genetics and Reproduction
- Virus-based gene therapy research
- Glutathione Transferases and Polymorphisms
- Aquaculture Nutrition and Growth
- bioluminescence and chemiluminescence research
- Biochemical Acid Research Studies
- Aquatic Ecosystems and Phytoplankton Dynamics
- Autophagy in Disease and Therapy
- Endoplasmic Reticulum Stress and Disease
- Banking stability, regulation, efficiency
- Selenium in Biological Systems
- Diatoms and Algae Research
- MicroRNA in disease regulation
- Marine Biology and Ecology Research
- Natural product bioactivities and synthesis
- Plant tissue culture and regeneration
- Moringa oleifera research and applications
- Insect Resistance and Genetics
- Aquaculture disease management and microbiota
- Epigenetics and DNA Methylation
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Credit Risk and Financial Regulations
- Polysaccharides and Plant Cell Walls
HUTECH University
2024
Thai Nguyen University
2016-2024
Institute of International Education
2024
Ho Chi Minh City University of Technology
2022-2024
James Cook University Singapore
2024
University of Tsukuba
2016-2023
Biotechnology Research Center
2020-2023
University of the Sciences
2015
Nrf2 plays critical roles in animals' defense against electrophiles and oxidative stress by orchestrating the induction of cytoprotective genes. We previously isolated zebrafish mutant it768, which displays up-regulated expression target genes an uninduced state. In this paper, we determine that gene responsible for it768 was homolog phosphomannomutase 2 (Pmm2), is a key enzyme initial steps N-glycosylation, its mutation humans leads to PMM2-CDG (congenital disorders glycosylation), most...
The Keap1–Nrf2 pathway is an evolutionarily conserved mechanism that protects cells from oxidative stress and electrophiles. Under homeostatic conditions, Keap1 interacts with Nrf2 leads to its rapid proteasomal degradation, but when are exposed stress/electrophiles, senses them, resulting in improper interaction stabilization. therefore considered both "inhibitor" of "stress sensor" for activation. Interestingly, fish amphibians have two Keap1s (Keap1a Keap1b), while there only one mammals,...
Malabar red snapper (Lutjanus malabaricus) is an important and high-value aquaculture species in Singapore that attracting substantial interest new industry investment. The consistent production of good quality eggs step for establishing a selective breeding program the Singapore. To achieve improved spawning outcomes, reproductive studies are needed to address challenges seed production, such as limited success closed culture systems. However, despite its rising profile candidate need...
The Keap1‐Nrf2 system is an evolutionarily conserved defense mechanism against oxidative and xenobiotic stress. Besides the exogenous stress response, Nrf2 has been found to regulate numerous cellular functions, including protein turnover glucose metabolism; however, evolutionary origins of these functions remain unknown. In present study, we searched for novel target genes associated with zebrafish answer this question. A microarray analysis embryos that overexpressed revealed 115 candidate...
The Keap1–Nrf2 pathway is an evolutionarily conserved mechanism that protects cells from oxidative stress and electrophiles. Keap1 a repressor of Nrf2 in normal cellular conditions but also sensor for activation. Interestingly, fish amphibians have two Keap1s (Keap1a Keap1b), which Keap1b the ortholog mammalian Keap1. Keap1a, on other hand, gene found only amphibians, having been lost during evolution to amniotes. We previously shown keap1b-knockout zebrafish increased activity reduced...
In Vietnam, a great number of toxic substances, including carcinogens and procarcinogens, from industrial agricultural activities, food production, healthcare services are daily released into the environment. present study, we report development novel yeast-based biosensor systems to determine both genotoxic procarcinogens by cotransformation with two plasmids. One plasmid is carrying human CPR CYP (CYP3A4, CYP2B6, or CYP2D6) genes, while other contains RAD54-GFP reporter construct. The...
Yeast cells transformed with high-copy number plasmids comprising a green fluorescent protein (GFP)-encoding gene optimized for yeast under the control of new DIN7 or PLM2 and established RNR2 RAD54 promoters were used to assess genotoxic potential chemical compounds. The activity DNA-damaging agents was investigated by genotoxicity assays OxoPlate assay in presence various test fluorescence signal generated GFP response DNA damage related different concentrations analytes analyte-dependent...
The EXP1 gene encodes expansin, which has the ability to loosen plant cell wall. soybean expansin GmEXP1 is activated specifically during root elongation process, and thus it plays important roles in development. During drought period, changes pressure within fast development of allow plants collect water from deep soil, turn helps grow develop. In this study, we have successfully cloned generated a construct expressing recombinant protein tobacco plants. expressed transgenic passed on next...
Plant defensins are multifunctional small cysteine-rich proteins. They active against fungi, bacteria, and many viruses, they inhibit trypsin α-amylase activities. In this study, we expressed the maize defensin gene (ZmDEF1) in tobacco seeds order to establish basis for generating transgenic plants resistant weevils. The ZmDEF1 was isolated from Maison, a Vietnamese local cultivar, which is well known having highest resistance weevils among other cultivars. cloned into binary vector,...
This study explores the pivotal factors influencing adoption of International Financial Reporting Standards (IFRS) in banking sector Vietnam, focusing on perceptions its benefits, competence accountants, involvement managers, and guidance from accounting auditing community. Employing Exploratory Factor Analysis (EFA) data collected 236 professionals across accounting, auditing, banking, finance, research reveals that perceived benefits IFRS, active managerial participation, advice...
The Keap1 protein (Kelch-like ECH-related 1) and the Nrf2 transcription factor (NF-E2-related 2) are important systems for maintaining homeostasis, redox, metabolism. Based on Keap1/Nrf2 pathway, antioxidative mechanism of P. amarus extract (PAE) was predicted. In this paper, we evaluated protective effects PAE oxidative toxicity induced by sodium arsenite (NaAsO2) hydrogen peroxide (H2O2) in zebrafish larvae. We first determined that LC50 values NaAsO2, H2O2, at 3.5 days postfertilization...
The study aimed to produce fluorescent protein transgenic medaka Oryzias curvinotus (Nichols & Pope, 1927) as a novel strain of ornamental fish. These fish were produced by transferring plasmid consisting reporter gene and strong promoter into one-cell stage embryos. For this purpose, myosin light chain 2, but not other promoters, was mainly used. also evaluated the stability germline acquiring vivid phenotypes via transgenesis cyan (CFP) under control O. skeletal alpha-actin (OCacta)...
Abstract Angelfish ( Pterophyllum sp.) are attractive fish popular with aquarists. The introduction of fluorescent protein genes into angelfish has been reported, but specific techniques have not revealed. This study aimed to develop a strategy produce red (RFP) transgenic driven by the myosin light chain 2 (mylz2) promoter from zebrafish. A 1999 bp Mylz2 fragment was isolated zebrafish muscle genomic DNA. then cloned plasmid pDsred2-1 open-loop at restriction enzyme Sac I and Age sites...
The colloidal solutions of selenium nanoparticles (SeNPs) stabilised in water-soluble β-glucan were successfully prepared by the gamma ray (Co-60) irradiation method. saturation dose for complete reduction contained 40, 60, 80, 100, and 120 ppm Se4+ determined at 4, 6, 8, 10, 12 kGy, respectively. structural characteristic particle size analysed Fourier transform infrared spectrophotometer (FTIR) Dynamic light scattering (DLS). obtained results showed that increase concentration from 1 to 4%...