A5072591607- Circadian rhythm and melatonin
- High voltage insulation and dielectric phenomena
- Organic Electronics and Photovoltaics
- Photoreceptor and optogenetics research
- Robotic Locomotion and Control
- Light effects on plants
- BIM and Construction Integration
- Electrical Fault Detection and Protection
- Engineering Applied Research
- Advanced Sensor and Energy Harvesting Materials
- Advanced MEMS and NEMS Technologies
- Advanced Memory and Neural Computing
- Thin-Film Transistor Technologies
- Power Transformer Diagnostics and Insulation
- Conducting polymers and applications
- Peroxisome Proliferator-Activated Receptors
- Nanowire Synthesis and Applications
- Semiconductor materials and devices
- Sleep and Wakefulness Research
- Synthesis and properties of polymers
- Risk and Safety Analysis
- Dielectric materials and actuators
- Biomimetic flight and propulsion mechanisms
- Adipose Tissue and Metabolism
- Spaceflight effects on biology
Saitama Medical University
2014-2024
Pakistan Nuclear Regulatory Authority
2016-2023
Sultan Zainal Abidin University
2015-2019
Nippon Kayaku (Japan)
2001-2018
Okayama University
2011-2017
Clock Spring (United States)
2017
Showa University
2017
Center For Children With Special Needs
2017
Okayama University of Science
2013
Kyushu University
2010-2011
2,7-Dialkyl[1]benzothieno[3,2-b]benzothiophenes were tested as solution-processible molecular semiconductors. Thin films of the organic semiconductors deposited on Si/SiO2 substrates by spin coating have well-ordered structures confirmed XRD analysis. Evaluations devices under ambient conditions showed typical p-channel FET responses with field-effect mobility higher than 1.0 cm2 V-1 s-1 and Ion/Ioff approximately 10(7).
As highly efficient organic sensitizers for dye-sensitized solar cells, a series of novel oligoene dyes which have different lengths methine units, cyano groups and/or carboxylic as the electron acceptor and amino donor units was designed synthesized. The bathochromic shift absorption spectrum achieved by expansion π-conjugated system increasing number introduction both electron-withdrawing -accepting groups, induced charge-transfer-type character. Redox potential also controlled...
A series of alkylated dinaphtho[2,3-b:2′,3′-f]thieno[3,2-b]thiophenes (Cn-DNTTs) were developed as vapor-processable organic semiconductors for thin-film transistors (OTFTs). All the Cn-DNTT-based OTFTs showed typical p-channel FET characteristics and among them, C10-DNTT possessing two n-decyl groups gave excellent under ambient conditions with mobility close to 8.0 cm2 V−1 s−1 Ion/Ioff > 108. Detailed facts importance specialist readers are published "Supporting Information". Such...
Bottom-gate, top-contact organic thin-film transistors (TFTs) with excellent static characteristics (on/off ratio: 107; intrinsic mobility: 3 cm2 (V s)−1) and fast unipolar ring oscillators (signal delay as short 230 ns per stage) are fabricated. The significant contribution of the transfer length to relation between channel length, contact resistance, effective mobility, cutoff frequency TFTs is theoretically experimentally analyzed. Detailed facts importance specialist readers published...
Flexible transistors and circuits based on dinaphtho-[2,3-b:2′,3′-f]thieno[3,2-b]thiophene (DNTT), a conjugated semiconductor with large ionization potential (5.4 eV), are reported. The have mobility of 0.6 cm2 V−1 s−1 the ring oscillators stage delay 18 µs. Due to excellent stability semiconductor, devices maintain 50% their initial performance for period 8 months in ambient air. Detailed facts importance specialist readers published as "Supporting Information". Such documents...
A convenient one-pot procedure for the synthesis of benzo[b]thiophenes and selenophenes from readily available o-halo-ethynylbenzene precursors is described. Regardless substituent on acetylene terminus or number cyclization moieties precursors, various selenophenes, including not only parent, alkyl-, phenyl-substituted derivatives but also benzo[1,2-b:4,5-b']dithiophenes diselenophenes benzo[1,2-b:3,4-b':5,6-b'']trithiophenes triselenophenes can be prepared in good to high yields.
Abstract A sheet‐type Braille display operating at 4 V has been successfully fabricated by integrating organic an static random‐access memory (SRAM) array with carbon nanotube (CNT)‐based actuators that are driven thin‐film transistors (control‐TFTs). The on current of control‐TFTs drive CNT exceeds 3 mA, the mobility 1 cm 2 −1 s , and on/off ratio 10 5 operational voltage V. By adjusting process time for formation aluminum oxide dielectrics, threshold TFTs can be systematically controlled....
To suppress undesirable short-channel effects in organic transistors with nanoscale lateral dimensions, aggressive gate-dielectric scaling (using an ultra-thin monolayer-based gate dielectric) and area-selective contact doping a strong dopant) are introduced into channel lengths gate-to-contact overlaps of about 100 nm. These have off-state drain currents below 1 pA, on/off current ratios near 107, clean linear saturation characteristics. Organic thin-film (TFTs) interest for electronic...
Compounds targeting the circadian clock have been identified as potential treatments for clock-related diseases, including cancer. Our cell-based phenotypic screen revealed uncharacterized clock-modulating compounds. Through affinity-based target deconvolution, we GO289, which strongly lengthened period, a potent and selective inhibitor of CK2. Phosphoproteomics multiple phosphorylation sites inhibited by GO289 on proteins, PER2 S693. Furthermore, exhibited cell type-dependent inhibition...
Chronic treatment of methamphetamine (MAP) in rats desynchronized the locomotor activity rhythm from light-dark cycle. When was completely phase-reversed with respect to a light dark-cycle, 24 h profiles were examined for clock gene (rPer1, rPer2, rBMAL1, rClock) expressions several brain structures by situ hybridization, and pineal as well plasma melatonin levels. In MAP-treated rats, rPer1 expression suprachiasmatic nucleus (SCN) showed robust circadian which essentially identical that...
Lipid absorption and metabolism are regulated by feeding the circadian system. It has been suggested that expression of enzymes involved in lipid is directly controlled clock This study was designed to examine whether or not CLOCK/BMAL1 heterodimer transcriptional activity for genes via peroxisome proliferator-activated receptor response element (PPRE). Male mice 8-12 weeks old were maintained under a 12:12 hour light-dark cycle at least two before day experiment. The mRNA profiles BMAL1...
The high performance of n-type organic thin-film thermoelectric elements utilizing a bilayer structure composed C60 and Cs2CO3 was demonstrated. By employing an underlying layer, the electrical conductivity power factor were significantly improved, maximum 20.5 μW m−1 K−2 at room temperature In addition, p-n prototype thermovoltaic device
Reporter assays that use luciferase are widely employed for monitoring cellular events associated with gene expression. In general, firefly and Renilla used single However, the expression of more than one cannot be monitored simultaneously by this system because two reporting luciferases must as an internal control. We have developed a novel reporter assay in which three emit green, orange, red light substrate genes. The activities can measured quantitatively optical filters. This enables us...
Pseudo-CMOS inverters operating at 2 V and comprising four p-type organic transistors with ultrahigh gain are fabricated using self-assembled monolayer gate dielectrics. The inverter is as large 302 an operation voltage of V, whereas the minimum small 0.5 V. oscillation frequency a five-stage ring oscillator pseudo-CMOS 4.27 kHz corresponding to 23.4 μs propagation delay per stage. This fastest among circuits low voltage. amplifier show 240 for 3.0-mV input
Circadian rhythms are generated by an extremely complicated transcription–translation feedback loop. To precisely analyze the molecular mechanisms of circadian clock, it is critical to monitor multiple gene expressions and/or interactions with their transcription factors simultaneously. We have developed a novel reporter assay system, tricolor in vitro which consists green‐ and red‐emitting Phrixothrix luciferases as dual reporters blue‐emitting Renilla luciferase internal control....
Evaluation of circadian phenotypes is crucial for understanding the pathophysiology diseases associated with disturbed biological rhythms such as rhythm sleep disorders (CRSDs). We measured clock gene expression in fibroblasts from individual subjects and observed cells (in vitro rhythms). Period length period) was compared intrinsic period, τ, under a forced desynchrony protocol vivo circadian/sleep parameters evaluated by questionnaires, log, actigraphy. Although no significant correlation...