- Sleep and Wakefulness Research
- Sleep and related disorders
- Welding Techniques and Residual Stresses
- Soil Carbon and Nitrogen Dynamics
- Vehicle emissions and performance
- Soil and Unsaturated Flow
- Circadian rhythm and melatonin
- Advanced Welding Techniques Analysis
- Congenital Heart Disease Studies
- Air Quality and Health Impacts
- Catalytic Processes in Materials Science
- Soil and Water Nutrient Dynamics
- Obstructive Sleep Apnea Research
- Memory and Neural Mechanisms
- Cardiac Imaging and Diagnostics
- Glaucoma and retinal disorders
- Organic Food and Agriculture
- Engineering Applied Research
- Aortic aneurysm repair treatments
- Catalysis and Oxidation Reactions
- Groundwater flow and contamination studies
- Hydraulic and Pneumatic Systems
- Microstructure and Mechanical Properties of Steels
- Tumors and Oncological Cases
- EEG and Brain-Computer Interfaces
Toyo University
2024
The Ohio State University
2013-2022
Hitachi (Japan)
2013-2022
Mie University
2021-2022
Tokyo University of Agriculture
2017-2022
Hashimoto Municipal Hospital
2022
Nippon Shinyaku (Japan)
2021
Gunma University
2019
Tokyo Denki University
2018
Meiji University
2015-2017
To clarify the neural correlates and brain activity during progression of human non-rapid eye movement (NREM) sleep, we examined absolute regional cerebral blood flow (rCBF) light deep NREM sleep wakefulness in normal humans using positron emission tomography with H 2 15 O. Relative changes rCBF comparison to were also analyzed. During midbrain, contrast that pons thalamic nuclei, did not decrease when compared wakefulness, whereas decreased left medial frontal gyrus, inferior parietal gyrus...
Labile pools of soil organic carbon (SOC) and nitrogen (N) are affecting the (C) N fluxes in terrestrial soils, whereas long-term C storage is determined by long-lived recalcitrant fractions. Tillage subsurface drainage influences these pools; however, effect systems on poorly drained soils may be different. Therefore, present study was conducted a field experiment, established at Waterman Farm Ohio State University 1994. Specific objectives to assess influence no-tillage (NT), chisel...
Abstract Introduction Latanoprostene bunod (LBN) is a novel nitric oxide (NO)-donating prostaglandin F2α analog. We evaluated the long-term safety and intraocular pressure (IOP)-lowering efficacy of LBN ophthalmic solution 0.024% over 1 year in Japanese subjects with open-angle glaucoma (OAG) or ocular hypertension (OHT). Methods This was single-arm, multicenter, open-label, clinical study. Subjects aged 20 years older diagnosis OAG OHT instilled drop affected eye(s) once daily evening for...
inveStigAtionS objective: To evaluate the health-related quality life (HRQOL) of drugnaïve patients with narcolepsy cataplexy (NA CA), without CA) and idiopathic hypersomnia long sleep time (IHS LST), to explore factors influencing HRQOL.Factors associated occurrence automobile accidents are also discussed.Methods: A total 137 consecutive drug naïve who met criteria 2nd edition International Classification Sleep Disorders CA, n = 28; NA 27; IHS LST, 82) were enrolled.The asked fill out...
The objective of this study was to clarify sleep characteristics and pathophysiology in patients with delayed phase syndrome (DSPS), which is a major circadian rhythm disorder subtype.Polysomnography performed for 2 consecutive nights core body temperature sampled 7 days, including the polysomnography period, all subjects. Findings were compared statistically analyzed between DSPS matched controls.Sleep disorders unit National Center Hospital.11 11 age-matched healthy volunteers.N/A.Sleep...
The demand for renewable energy resources, such as Miscanthus spp., has increased significantly in temperate regions. spp. the potential to mitigate GHG emissions by replacing fossil fuels and sequestering carbon soil. However, biomass yield C sequestration performance of varies climate, soil type, management practices, land-use history. Therefore, there is a need site-specific research on × giganteus (M g). An alternative M g seed-propagated sinensis which could be another option bioenergy...
To evaluate the long-term efficacy and safety of ripasudil-brimonidine fixed-dose combination (RBFC), a new intraocular pressure (IOP)-lowering medication for glaucoma ocular hypertension (OHT).
The effects of papaverine, a smooth muscle relaxant agent, on the voltage-dependent Ca++ current were examined in isolated cells from guinea pig trachea. tight-seal whole cell voltage clamp technique was used. Papaverine (1-100 microM) inhibited Ba++ inward (IBa) through L-type channel concentration-dependent fashion. inhibitory effect papaverine IBa appeared to have both tonic and use-dependent components. In addition reduction maximal conductance IBa, (20 shifted quasi-steady-state...
Intensive tillage practices and poorly drained soils of the Midwestern United States are one prime reasons for increased greenhouse gas (GHG) fluxes from agriculture. The naturally prevalent in this region require subsurface drainage improving aeration reducing GHG soils. However, very little research has been conducted on combination impacts Thus, present study was central Ohio with specific objective to assess influences long-term (18-year) no-tillage (NT) chisel-till (CT) carbon dioxide...
Kinetic studies of the partial oxidation CH4 over Sm2O3 using N2O and O2 as oxidants have been carried out at 823–950 K kinetic features in reactions with compared. At a low temperature (823 K) pressure 3–13 kPa, by produced C2H6 high selectivity, but only deep took place when was used oxidant. However, observable lowered below 1kPa. The reactivity two orders magnitude greater than that N2O. is better oxidant for production C2 compounds. A reaction mechanism CH4with proposed. shown...
The excessive intake of sodium (Na) and insufficient potassium (K) are major concerns to prevent hypertension. Using low-Na/K seasonings (reducing 25% the NaCl adding K salt) may improve dietary Na/K ratio help To devise an intervention study using at a company cafeteria, we calculated Na contents meals served cafeteria estimated changes in intakes when suitable were used. We also considered milk as good source K. used ingredient list each dish. average amounts per use 5.04 g 718 mg,...
Summary: The anticholinergic effects of cibenzoline were examined and compared with those disopyramide in atrial myocytes isolated from guinea pig heart. tight-seal whole-cell voltage clamp technique was performed a patch pipette filled guanosine-5′-triphosphate (GTP) or guanosine-5′-O-(3-thiotriphosphate) (GTP-γS). In GTP-loaded cells, both acetylcholine (ACh) adenosine (Ado) induced specific K channel current through GTP-binding proteins by binding to the muscarinic Ado receptors,...
The authors' goal was to identify differences in regional brain activity between physiological and benzodiazepine-induced sleep clarify the structures involved drug's hypnotic effect.Using positron emission tomography, they compared cerebral blood flow during non-REM nine volunteers treated with placebo or triazolam, a short-acting benzodiazepine, double-blind, crossover design.Blood basal forebrain amygdaloid complexes lower when subjects were given triazolam than placebo.The effect of...