A5062341917- Animal Virus Infections Studies
- Single-cell and spatial transcriptomics
- Immune cells in cancer
- vaccines and immunoinformatics approaches
- Sparse and Compressive Sensing Techniques
- SARS-CoV-2 and COVID-19 Research
Engelhardt Institute of Molecular Biology
2021-2022
Since the outbreak of SARS-CoV-2, etiologic agent COVID-19 pandemic, viral genome has acquired numerous mutations with potential to alter infectivity and antigenicity. Part in SARS-CoV-2 spike protein conferred virus ability spread more quickly escape from immune response caused by monoclonal neutralizing antibody or vaccination. Herein, we summarize spatiotemporal distribution protein, present recent efforts progress investigating impacts those on As continue emerge strive provide...
The rapid development of single-cel+l RNA sequencing (scRNA-seq) technology provides unprecedented opportunities for exploring biological phenomena at the single-cell level. discovery cell types is one major applications researchers to explore heterogeneity cells. Some computational methods have been proposed solve problem scRNA-seq data clustering. However, unavoidable technical noise and notorious dropouts also reduce accuracy clustering methods. Here, we propose cauchy-based bounded...