A5011439666- Sinusitis and nasal conditions
- Temporomandibular Joint Disorders
- Asthma and respiratory diseases
- Obstructive Sleep Apnea Research
- Allergic Rhinitis and Sensitization
- Nasal Surgery and Airway Studies
- Orthodontics and Dentofacial Orthopedics
- Dental Research and COVID-19
- Head and Neck Surgical Oncology
- Dental Implant Techniques and Outcomes
- Infection Control and Ventilation
- Vestibular and auditory disorders
- COVID-19 and healthcare impacts
- Dental Health and Care Utilization
- Oropharyngeal Anatomy and Pathologies
- Cleft Lip and Palate Research
- Cardiovascular and Diving-Related Complications
- Trauma and Emergency Care Studies
- Sympathectomy and Hyperhidrosis Treatments
- Scientific and Engineering Research Topics
- Head and Neck Cancer Studies
- Tracheal and airway disorders
- Dermatological and COVID-19 studies
- Oral and Craniofacial Lesions
- Scoliosis diagnosis and treatment
Ospedale di Rivoli
2020-2025
Università Cattolica del Sacro Cuore
2020-2024
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2021
University of L'Aquila
2021
Agostino Gemelli University Polyclinic
2019-2020
Istituti di Ricovero e Cura a Carattere Scientifico
2019-2020
The article is aimed at improving the understanding of sociocultural profile adult orthodontic patients and their expectations. In particular, it addresses three main aspects: motivation needs that underpin decision to start treatment, how influences patients' daily life, different oral hygiene demands.An online survey was completed by 276 undergoing treatment with techniques. questions asked concerned gender, age, type appliance, any previous treatments, retainers, reasons for therapy,...
Chronic rhinosinusitis with nasal polyps (CRSwNP) may have a heterogeneous response to medical/surgical treatments based on endotypes. Data correlating biomarkers and severity of the disease are lacking. We aimed determine if IL-5 calprotectin be useful in defining identifying uncontrolled patients.
Management of severe chronic rhinosinusitis with nasal polyps (CRSwNP) has changed significantly in recent years, different treatments now available including biologics and endoscopic sinus surgery (ESS), although there are still few comparative studies. We aimed to compare 1-year outcomes patients CRSwNP treated dupilumab or ESS plus intranasal corticosteroids (INCS).
Temporomandibular disorders are multi-factorial conditions that caused by both physical and psychological factors. It has been well established stress triggers or worsens TMDs. This paper looks to present early research, still unfolding, on the relationship between COVID-19 as a major life stressor The main aims of this study were to: investigate presence symptoms related TMDs time onset worsening painful in relation changes social imposed coronavirus pandemic; evaluate perception stressful...
Promotion of oral health has an essential role in the maintenance teeth adults. However, education must start from early age, order to monitor child's growth and prevent pathologies. Schools are charge overall children guidance parents but could also be engaged promotion health, supported counseled by pediatricians dentists. The purpose this pilot study is evaluate whether school age taught, successfully, basic sciences dental hygiene, a professional, during hours. In study, anonymized test...
The complex pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP) generates a spectrum phenotypes wide variety inflammatory states. We enrolled 44 very-likely-to-be type 2 CRSwNP patients in order to evaluate the load inflammation and analyze human interleukins secretion. Clinical data were collected severity disease. High levels IL-5, IL-4, IL-6, IL-33 detected all patients. By analyzing cytokine profiles local eosinophil count, we identified two coherent clusters: first was...
Background/Objectives: Benralizumab is a monoclonal antibody that targets the interleukin-5 receptor (IL-5Rα), leading to rapid depletion of blood eosinophils. RCTs have demonstrated efficacy in patients with severe eosinophilic asthma (SEA). The aim this study was assess benralizumab on sinonasal outcomes real-life setting SEA and concomitant chronic rhinosinusitis nasal polyps (CRSwNP). Methods: We included 25 (mean age: 57.47 years, range: 35–77, F/M = 12:13) who were prescribed 30 mg...
in the era of new biological agents it is important to identify patients who may benefit from conventional therapies such as endoscopic sinus surgery (ESS) plus long-term local corticosteroids those with patterns inflammation that are more difficult control post-operatively and other therapies.determine if preoperative assessment type grade clinical factors can predict disease ESS chronic rhinosinusitis nasal polyps (CRSwNP).Eighty treated mometasone-furoate 200 μg BID for CRSwNP followed at...
ABSTRACT Objective The aim of this study was to evaluate if dupilumab interval dose de‐escalation every 4 weeks negatively impacts treatment outcomes in real‐life practice for severe uncontrolled chronic rhinosinusitis with nasal polyps (CRSwNP) during the first 2 years treatment. Methods We enrolled 148 patients who completed follow‐up. compared two homogenous groups terms severity: group A included 77 never modified administration follow‐up; B 71 extended dosing monthly administration. and...
Mandibular reposition devices (MRDs) are a viable option for addressing snoring and mild to moderate obstructive sleep apnea syndrome (OSAS) as another possibility continuous positive airway pressure (CPAP) ventilation during sleep. The aim of the study was evaluate efficacy OSAS MRDs with variation in vertical dimension, considering indexes: Apnea Hypopnea Index (AHI), Oxygen Desaturation (ODI) Snoring Index. Eleven patients different level were enrolled this study. evaluated at three times...
Scoliosis is a complex three-dimensional malformation of the spine. Although its etiology still being investigated, it clear that number factors can influence this syndrome. The spinal deformity idiopathic scoliosis be viewed from an etiopathogenetic perspective as symptom complicated condition with multifactorial etiology. Numerous studies have established relationship malocclusion, but unclear how these interact. Malocclusion change in physiological alignment upper and lower teeth either...
Introduction: Obstructive sleep apnea syndrome (OSAS) is a disorder characterized by partial or total airway obstruction during sleep. Studies have shown variability in the level of knowledge and awareness about OSAS among pediatricians. The management childhood obstructive depends on severity disease, presence comorbidities, child’s age. American Pediatric Academy recommends multidisciplinary approach involving pediatrician, specialist, an otolaryngologist to provide comprehensive care for...
The aim of this study was to evaluate the clinical relevance absolute eosinophil blood count and by nasal cytology in context real-life practice determine if they correlate with severity symptoms patients chronic rhinosinusitis polyps (CRSwNP). We enrolled 425 CRSwNP followed between January 2015 April 2023 at A. Gemelli Hospital Foundation-IRCCS, Rome, Italy. gathered data on local correlated results features. All underwent endoscopy, Visual Analogical Scale (VAS) for main symptoms,...
Abstract COVID-19 negatively affected surgical activity, but the potential benefits resulting from adopted measures remain unclear. The aim of this study was to evaluate change in activity and benefit perspective Italian surgeons on behalf SPIGC. A nationwide online survey practice before, during, after pandemic conducted March–April 2022 (NCT:05323851). Effects hospital-related patients’ management personal professional development across specialties were explored. Data demographics,...
Abstract Objective The purpose of this cross-sectional observational study was to evaluate the effects SpO2 in a sample dental health care providers who wear N95 mask or Filtering Face Piece (FFP2) for four consecutive hours, measured by pulse oximeter before donning and again after hours work offer some strategies minimize discomfort improve communication with their patients while wearing mask. Materials methods A 17-item questionnaire sent via Google Drive various practitioners Italy USA....
Nowadays, aligners represent a possible therapeutical approach that combines both esthetic and function in order to address dental malocclusion. However, they require significant level of compliance from the patient. According manufacturer, at least 22 h wearing day is demanded reach optimal level; hence, can only be removed during meals. Patients’ might increase duration treatment decrease if were allowed eat with on. The idea patients keeping on meals has been contemplated, not favor...
Over the past 20 years, there have been many innovations in orthodontic diagnosis and therapy. Among innovations, is taking of dental impressions (DIs). Dental are negative imprint hard soft tissues one or both arches, they allow a plaster model to be formed, i.e., positive reproduction. Traditional can made different materials, such as alginate, while digital impression captured by an intra-oral scanner. Digital impression, despite evident advantages, has not yet replaced conventional...
Background: the primary end point of our study was to define risk factors and identify underlying conditions that may have led abuse vasoconstrictors in rhinitis medicamentosa.Moreover, we analysed influence discontinuation.Methodology: this a prospective case-control observational study.Cases controls were evaluated at baseline order influenced onset medicamentosa.They re-evaluated 3 months verify symptoms control drug discontinuation.Finally, they underwent phone call questionnaire after...
The pandemic of the 21st century had a significant influence on lives world population in negative way. This situation determined change lifestyle; it caused necessity social isolation for great number people. In fact, people tended to avoid crowded environments, events, reduce medical checks and sports activities, favoring sedentary life because fear virus. attitude brought high level stress that worsened many health conditions. study has aim evaluating possible temporomandibular joint...
The present observational prospective study analyzes the eating habits in association with medico-oral health of catering workers, since they seem category at higher risk developing dental problems. Objective: To evaluate oral and medical through a questionnaire total sample 603 participants. Additionally, this article aims to provide information regarding implications an unbalanced diet linked particular profession. Material methods: A created Google Forms platform was sent all members...
We analysed calprotectin in sinonasal secretions of different chronic rhinosinusitis with nasal polyps (CRSwNP) endotypes to assess its role as a biomarker non-type 2 inflammation.We included primary diffuse CRSwNP patients (n = 41) and three control groups [non-allergic rhinitis (NAR) 13), non-allergic eosinophilic syndrome (NARES) 10) healthy subjects 12)]. Calprotectin levels were detected using chemiluminescent immunoassay (CLIA).Calprotectin significantly higher all compared controls (p...
Objectives/Hypothesis To analyze stapler benefits in salvage total laryngectomy terms of surgical time, hospitalization length, oral feeding and occurrence pharyngocutaneous fistula, to evaluate risk factors for its onset. Study Design Retrospective analysis. Methods One hundred fourteen patients affected by endolaryngeal squamous cell carcinoma who underwent following primary treatment failure were reviewed. We divided into two groups based on type pharyngeal suture performed: mechanical...
Sudden sensorineural hearing loss (SSHL) is a relatively frequent disease, but sensitive marker or reliable test to identify the underlying cause still unavailable. Neuroradiology appears offer most promising tools, especially magnetic resonance imaging (MRI). In recent study from our group, we explored ability of MRI detect subtle changes in inner ear compartments by means 3D-fluid-attenuated inversion recovery sequence, aiming at identifying 3 distinct patterns (haemorrhagic, inflammatory,...
Mandibular setback surgery (MSS) is one of the treatment options to resolve mandibular prognathism in patients suffering from skeletal class III malocclusion, which cannot be treated with simple orthodontic treatment. The surgical operation can involve changes pharyngeal morphology, resulting a narrowing posterior airway space (PAS). This aspect associated an increase airflow resistance, increases risk developing snoring or obstructive sleep apnea syndrome (OSAS). aim this study evaluate...