A5103256758- Retinal Development and Disorders
- Glaucoma and retinal disorders
- Retinal Diseases and Treatments
- Photoreceptor and optogenetics research
- Retinal and Optic Conditions
- Migraine and Headache Studies
- Neuroscience and Neural Engineering
- Retinal Imaging and Analysis
- Neurological Disorders and Treatments
- Visual perception and processing mechanisms
- Receptor Mechanisms and Signaling
- Transcranial Magnetic Stimulation Studies
- Optical Imaging and Spectroscopy Techniques
- S100 Proteins and Annexins
- Circadian rhythm and melatonin
- Malaria Research and Control
- Retinal and Macular Surgery
- Epilepsy research and treatment
- Ocular and Laser Science Research
- Connexins and lens biology
- Intraocular Surgery and Lenses
- Neurofibromatosis and Schwannoma Cases
- Photoacoustic and Ultrasonic Imaging
- Retinopathy of Prematurity Studies
- Molecular spectroscopy and chirality
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2024
Bambino Gesù Children's Hospital
2024
Agostino Gemelli University Polyclinic
2020-2024
Università Cattolica del Sacro Cuore
2002-2019
National Eye Institute
2013-2016
Catholic University of America
1999-2008
National Research Council
1989-1993
University of the Sacred Heart
1991-1992
Diabetic retinopathy (DR) affects almost 30% of patients with diabetes mellitus (DM), and proliferative diabetic (PDR) involves 9% them consequent severe visual impairment (Cheung et al. 2010). Proliferative represents a heightened risk life-threatening systemic vascular complications occurs due to glycaemic long periods metabolic alterations. The natural evolution PDR is characterized by series clinical signs, starting retinal ischaemia an abnormal activation endothelial growth factor...
Abstract Background To study the photopic negative response of full‐field electroretinography (ERG) in Stargardt patients with pathogenic variants ABCA4 gene. Methods A retrospective analysis 35 gene variants, compared to normal age‐matched controls. Patients were clinically followed at Ophthalmology Department Fondazione Policlinico Universitario A. Gemelli/Università Cattolica del Sacro Cuore, Rome, Italy. Results The ERG was compromised most patients. In presence a B‐wave, amplitude ratio...
We evaluated in ocular hypertension (OHT) and early glaucoma (EOAG) patients the optic nerve head (ONH) blood flow response (RF onh ) to chromatic equiluminant flicker. This stimulus generates neural activity dominated by parvo-cellular system. Eleven EOAG, 20 OHT patients, 8 age-matched control subjects were examined. The (F at neuroretinal rim was continuously monitored laser Doppler flowmetry before, during, after a 60-s exposure 4 Hz, red-green flicker (30 deg field). RF expressed as...
Background It is still debatable whether the mechanisms underlying photophobia are related to altered visual cortex excitability or specific abnormalities of colour-related focal macular retino-thalamic information processing. Methods This cross-sectional study examined Ganzfeld blue-red (B-R) and blue-yellow (B-Y) cone flash ERG (ffERG) focal-flash evoked potentials (ffVEPs) simultaneously in a group migraine patients with (n = 18) without 19) aura during interictal phase, comparison...
Background Recent experimental evidence points out a possible involvement of outer and inner retinal layers in hypersensitivity migraine patients to light stimuli. To investigate the short-wavelength-sensitive (S) medium/longwavelength-sensitive (ML) cone photoreceptors visual pathways without aura (MO) between attacks healthy volunteers (HV) by using yellow-blue (Y-B) or red-blue (R-B) flicker
In the field of Electroretinography (ERG), new clinical studies begin to show interesting applications harmonic analysis electrophysiological signals obtained in response flicker-type stimulation central retina (macula). The information within this type signal can be fully exploited only if experiments are performed using high quality devices, having low distortion and a wide operation range for parameters. view we developed stand-alone stimulator that takes advantage from use recent...
We aimed to investigate the visual evoked potential (VEP) in children unconscious with <i>Plasmodium falciparum</i> malaria, a common cause of death Africa. Flash VEPs were carried out Malawi during one peak malaria season. Children included study if they had <i>P. and reduced consciousness – Blantyre Coma Score (BCS) 4 or less 5. Initial performed after stabilising patient commencing treatment. To optimal VEP protocols, varying stimulus parameters tested. Where possible, repeated daily...