A5086343918- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Total Knee Arthroplasty Outcomes
- Orthopaedic implants and arthroplasty
- Rheumatoid Arthritis Research and Therapies
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Knee injuries and reconstruction techniques
- Scoliosis diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Orthopedic Infections and Treatments
- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Cardiac electrophysiology and arrhythmias
- Musculoskeletal pain and rehabilitation
- Pelvic and Acetabular Injuries
- Bone and Joint Diseases
- Sarcoma Diagnosis and Treatment
- Bone health and osteoporosis research
- Osteoarthritis Treatment and Mechanisms
- Bone Tumor Diagnosis and Treatments
- Spondyloarthritis Studies and Treatments
- Bone fractures and treatments
- Peripheral Nerve Disorders
- Cardiac pacing and defibrillation studies
Osaka Metropolitan University
2021-2025
Tokyo Metropolitan University
2016-2025
Osaka City University
2015-2024
Toho University
1990-2024
Nemours Children’s Clinic
2024
Toho University Ohashi Medical Center
2015-2024
Kyowa Kirin (Japan)
2008-2024
Metropolitan University
2021-2024
Tokyo Metropolitan Bokutoh Hospital
2024
Yodogawa Christian Hospital
2010-2023
The heme compound found in deoxyribonucleic acid (DNA) extracted from bloodstains, which is regarded as a major inhibitor of polymerase chain reaction (PCR), was characterized comparison with alkaline and hematin, histidine ammonia hemochromogens, globin serum albumin hemochromogens digested by proteinase K. Alkaline hematin were almost completely removed phenol/chloroform treatment ethanol precipitation, so not to be copurified DNA the specimens. Spectrophotometric results indicated that...
A retrospective study.Purpose: This study aimed to determine the impact of increased Hounsfield unit (HU) values for metastatic spinal lesions measured via computed tomography on overall survival patients with non-small-cell lung cancer (NSCLC) and identify factors associated HU in lesions.Overview Literature: Previous studies have underscored utility as a marker treatment response bone lesions.However, no prior explored relationship between changes NSCLC.Methods: included total 85 2016...
Female sex is an independent risk factor for torsade de pointes in long-QT syndrome. In women, QT interval and fluctuate dynamically during the menstrual cycle pregnancy. Accumulating clinical evidence suggests a role progesterone; however, effect of progesterone on cardiac repolarization remains undetermined.We investigated effects action potential duration membrane currents isolated guinea pig ventricular myocytes. Progesterone rapidly shortened duration, which was attributable mainly to...
In Brief Study Design. Prospective multicenter study. Objective. To identify radiographic or magnetic resonance (MR) images of fresh vertebral fractures that can predict a high risk for delayed union nonunion osteoporotic (OVFs). Summary Background Data. Vertebral body are the most common in osteoporosis patients. Conservative treatments typically chosen OVFs, and associated back pain generally subsides within several weeks with residual persistent deformity body. some patients, OVF healing...
A cross-sectional imaging study of paraspinal muscle degeneration using a new index for easy evaluation.To examine the natural progression age-related changes in lumbar muscles and to verify validity our evaluating degenerationSUMMARY OF BACKGROUND DATA.: Measurement morphology is an effective method reflecting atrophy fat infiltration, but it complicated perform. Therefore, we focused on groove between as simple degeneration.A total 160 subjects aged 10 88 years (10 male female each decade)...
A prospective observational study.To evaluate the paravertebral muscle (PVM) degeneration in patients with degenerative lumbar scoliosis (DLS), using magnetic resonance imaging.Several studies have described histological and morphological changes to PVM chronic low back pain radiculopathy. However, there is little knowledge about DLS.Fifty-seven spinal stenosis (LSS) DLS (DLS group) 50 control LSS without (LSS were examined. The cross-sectional area (CSA) percentage of fat infiltration...
Major salivary gland ultrasonography (SGUS) is widely used for the diagnosis of primary Sjögren's syndrome (pSS). Our objective was to assess contribution SGUS compared other items 2016 ACR/EULAR pSS classification criteria, based on expert opinion.A secure web-based relational database by 24 experts from 14 countries 512 realistic vignettes developed data patients with suspected pSS. Each vignette provided criteria and information history, clinical symptoms findings. assessed 64 vignettes,...
<h3>Abstract</h3> <h3>Background</h3> The COVID-19 pandemic has caused interruptions to chronic disease and non-emergency treatment. purpose of this study is examine which socioeconomic status groups are most at risk treatment interruption. <h3>Methods</h3> This cross-sectional internet monitor was conducted on December 22–26, 2020, when Japan experienced its third wave infection. Out a total 33,302 participants in the survey, 9510 (5392 males 4118 females) who responded that they required...
In Brief Study Design. Retrospective review. Objective. Evaluation of the impact diabetes on lumbar spine surgery. Summary Background Data. Characteristics that increase risk postoperative complications and poor surgical outcomes after surgery remain unclear. Methods. The demographic clinical data diabetic nondiabetic patients, 50 years or older, undergoing were reviewed. Japanese Orthopaedic Association visual analogue scale scores for low back pain, leg numbness assessed as perioperative...
Various modifications including addition of Schwann cells or incorporation growth factors with bioabsorbable nerve conduits have been explored as options for peripheral repair. However, no reports containing both supportive and published a regenerative therapy nerves. In the present study, sciatic gaps in mice were reconstructed following groups: conduit alone (control group), coated induced pluripotent stem cell (iPSc)-derived neurospheres (iPSc iPSc-derived basic fibroblast factor...
Ultrastructural studies of thin-sectioned and freeze-cleaved materials were performed on developing retinal tissues 3- to 9-day-old chick embryos clarify the junctional structures between neural cells pigmented epithelium. Frequency, size position gap junctions in retina are different at each stage development. In 3-day-old embryos, some adhere other by immediately below outer limiting membrane retinae. The number increase remarkably during 5-6 days incubation. this period development, well...
The post-second-generation cryoballoon (CB) ablation isolation area during the chronic phase has not been described. aim of this study was to quantitatively evaluate chronic-phase after 28-mm second-generation CB and compare it estimated conventional radiofrequency circumferential pulmonary vein (CPVI) line.Thirty-two patients with paroxysmal atrial fibrillation underwent (PV) using CB. After a median 6.0 (4.0-9.0) months, PV evaluated high-resolution mapping (1-mm electrode, 2-mm...
Study Design. Retrospective analysis of consecutive 45 radiographs and 120 kinematic magnetic resonance images (kMRI) Objective. The aim was to assess the visibility C7 T1 endplates on radiographs, verify correlation between or slope cervical balance parameters using kMRI. Summary Background Data. Because is not always visible due anatomical interference, several studies have used instead T1. However, it still unclear whether endplate more than T1, if has similarity with slope. Methods....
Retrospective analysis of kinetic magnetic resonance images.To define the prevalence degenerative cervical spondylolisthesis in symptomatic patients and to analyze motion characteristics influence on spinal canal at affected level.When compared with lumbar spondylolisthesis, there are few studies evaluating not well defined.Four hundred sixty-eight underwent upright images neutral, flexion, extension positions. Segmental displacement intervertebral angles were measured 3 positions using...
To investigate the efficacy of transplantation autologous bone marrow-derived mesenchymal stem cells (BMSCs) under arthroscopy with microfracture (MFX) compared alone. Eleven patients a symptomatic articular cartilage defect knee were included in study. They randomized to receive BMSCs MFX (cell-T group, n=7) or alone (control n=4). Clinical results evaluated using International Knee Documentation committee (IKDC) evaluation questionnaires and Injury Osteoarthritis Outcome Score (KOOS)...
Worldwide prevalence of obesity is associated with the increase lifestyle-related diseases. The accumulation intermuscular adipose tissue (IMAT) considered a major problem whereby leads to sarcopenia and metabolic disorders thus promising target for treating these pathological conditions. However, whereas obesity-associated IMAT suggested originate from PDGFRα+ mesenchymal progenitors, processes underlying this adipogenesis remain largely unexplored. Here, we comprehensively investigated...
Background: Perioperative essential amino acid (EAA) supplementation suppresses lower-limb muscle atrophy and promotes functional improvement in the first 4 weeks after total knee arthroplasty (TKA). However, its effect on recovery of volume strength intermediate term is unclear. The aim this study was to evaluate perioperative EAA 2 years TKA. Methods: Sixty patients who underwent unilateral TKA for primary osteoarthritis were included double-blinded randomized controlled trial. After...