Alexandra S. Heerdt

ORCID: 0000-0002-3722-5743
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About
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Research Areas
  • Breast Cancer Treatment Studies
  • Breast Lesions and Carcinomas
  • Breast Implant and Reconstruction
  • BRCA gene mutations in cancer
  • Reconstructive Surgery and Microvascular Techniques
  • Global Cancer Incidence and Screening
  • Patient-Provider Communication in Healthcare
  • Cancer Diagnosis and Treatment
  • Cancer Genomics and Diagnostics
  • Optical Imaging and Spectroscopy Techniques
  • MRI in cancer diagnosis
  • Optical Polarization and Ellipsometry
  • Health Literacy and Information Accessibility
  • Social Media in Health Education
  • Cancer Risks and Factors
  • Cancer Treatment and Pharmacology
  • Nutrition, Genetics, and Disease
  • Estrogen and related hormone effects
  • HER2/EGFR in Cancer Research
  • Multiple and Secondary Primary Cancers
  • Asthma and respiratory diseases
  • Optical Coherence Tomography Applications
  • Mast cells and histamine
  • Prenatal Screening and Diagnostics
  • Allergic Rhinitis and Sensitization

Memorial Sloan Kettering Cancer Center
2015-2024

Cornell University
1995-2019

University of California, San Diego
2018

Defense Information Systems Agency
2003

American Society of Plastic Surgeons
2003

St. Jude Children's Research Hospital
1999

City University of New York
1996

The NCCN Guidelines for Breast Cancer Screening and Diagnosis have been developed to facilitate clinical decision making. This manuscript discusses the diagnostic evaluation of individuals with suspected breast cancer due either abnormal imaging and/or physical findings. For screening recommendations, please see full guidelines on NCCN.org.

10.6004/jnccn.2018.0083 article EN Journal of the National Comprehensive Cancer Network 2018-11-01

In Brief Objective: We sought to identify the rate of axillary recurrence after sentinel lymph node (SLN) biopsy for breast cancer. Summary Background Data: SLN is a new standard care staging in Nevertheless, most validated series confirm that falsely negative 5–10% node-positive cases, and few studies report local (LR) subset patients staged by alone. Methods: Through December 2002, 4008 consecutive procedures were performed at Memorial Sloan-Kettering Cancer Center unilateral invasive...

10.1097/01.sla.0000137130.23530.19 article EN Annals of Surgery 2004-08-19

Purpose To determine feasibility of performing bilateral dual-energy (DE) contrast agent–enhanced (CE) digital mammography and to evaluate its performance compared with conventional breast magnetic resonance (MR) imaging in women known cancer. Materials Methods This study was approved by the institutional review board HIPAA compliant. Written informed consent obtained. Patient accrual began March 2010 ended August 2011. Mean patient age 49.6 years (range, 25–74 years). Feasibility evaluated...

10.1148/radiol.12121084 article EN Radiology 2012-12-07

Background: Postmastectomy radiotherapy is increasingly common for patients with advanced breast cancer. The optimal timing and sequence of mastectomy, reconstruction, remains unresolved choosing immediate two-stage prosthetic reconstruction. Methods: Long-term outcomes were compared all prosthetic-based reconstruction without radiation, radiation to the tissue expander, or permanent implant from 2003 2012 performed by senior author (P.G.C.). Surgeon-evaluated included reconstructive...

10.1097/prs.0000000000001278 article EN Plastic & Reconstructive Surgery 2015-03-05

Prospective trials have demonstrated sentinel lymph node (SLN) false-negative rates of less than 10% when 3 or more SLNs are retrieved in patients with clinically node-positive breast cancer rendered node-negative neoadjuvant chemotherapy (NAC). However, nodal recurrence such treated SLN biopsy (SLNB) alone unknown because axillary dissection (ALND) was performed all patients, limiting adoption this approach.To evaluate a consecutive cohort (cN1) receiving NAC, followed by negative SLNB...

10.1001/jamaoncol.2021.4394 article EN JAMA Oncology 2021-10-10

MRI of Occult Breast Carcinoma in a High-Risk PopulationElizabeth A. Morris1, Laura Liberman1, Douglas J. Ballon2, Mark Robson3, Andrea F. Abramson1, Alexandra Heerdt4 and D. David Dershaw1Audio Available | Share

10.2214/ajr.181.3.1810619 article EN American Journal of Roentgenology 2003-09-01

In the United States, identification of sentinel lymph node (SLN) requires use 99mTc-labeled colloid, 1% isosulfan blue dye, or both to trace lymphatic drainage a given neoplasm. We report our experience with adverse reactions dye during SLN mapping in breast cancer. A chart review cancer database was performed; it included 2392 sequential patients who underwent biopsy involving at Memorial Sloan-Kettering Cancer Center from September 12, 1996, August 17, 2000. Thirty-nine (1.6%) had...

10.1097/00000539-200208000-00026 article EN Anesthesia & Analgesia 2002-08-01

Purpose To determine the immediate and long-term effects of true acupuncture versus sham on hot flash frequency in women with breast cancer. Patients Methods Seventy-two cancer experiencing three or more flashes per day were randomly assigned to receive either acupuncture. Interventions given twice weekly for 4 consecutive weeks. Hot was evaluated at baseline, 6 weeks, months after initiation treatment. initially group crossed over starting week 7. Results The mean number reduced from 8.7...

10.1200/jco.2007.12.0774 article EN Journal of Clinical Oncology 2007-12-07

Objective: To determine rates of axillary dissection (ALND) and nodal recurrence in patients eligible for ACOSOG Z0011. Background: Z0011 demonstrated that with cT1-2N0 breast cancers 1 to 2 involved sentinel lymph nodes (SLNs) having breast-conserving therapy had no difference locoregional or survival after SLN biopsy alone ALND. The generalizability the results importance radiotherapy (RT) is unclear. Methods: Patients alone. Prospectively defined indications ALND were metastases ≥3 SLNs...

10.1097/sla.0000000000002354 article EN Annals of Surgery 2017-06-23

Germline mutations in the BRCA1 and BRCA2 genes are associated with an increased risk of breast cancer. Whether women cancer who have inherited these a different outcome after conservation therapy than "sporadic" is unresolved. Consequently, we compared outcomes Ashkenazi or without germline and/or (hereafter called BRCA).We studied 305 Jewish descent undergoing breast-conserving treatment for 329 invasive cancers. We reviewed their clinical records, retrieved archival tissue samples, tested...

10.1093/jnci/91.24.2112 article EN JNCI Journal of the National Cancer Institute 1999-12-15

In the United States, identification of sentinel lymph node (SLN) requires use 99mTc-labeled colloid, 1% isosulfan blue dye, or both to trace lymphatic drainage a given neoplasm. We report our experience with adverse reactions dye during SLN mapping in breast cancer. A chart review cancer database was performed; it included 2392 sequential patients who underwent biopsy involving at Memorial Sloan-Kettering Cancer Center from September 12, 1996, August 17, 2000. Thirty-nine (1.6%) had...

10.1213/00000539-200208000-00026 article EN Anesthesia & Analgesia 2002-08-01

Background: The objective of this study was to analyze early complications and long-term outcomes in patients undergoing salvage mastectomy immediate tissue expander/implant reconstruction for cancer recurrence following breast conservation therapy (lumpectomy/irradiation). Methods: A review all reconstructions performed by a single surgeon over an 11-year period from 1997 2008 performed. Two patient cohorts were identified: (1) who underwent prior therapy, (2) primary without history...

10.1097/prs.0b013e318205f203 article EN Plastic & Reconstructive Surgery 2012-01-28
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