A5055640041- Amyloidosis: Diagnosis, Treatment, Outcomes
- Medical Imaging and Pathology Studies
- Eosinophilic Disorders and Syndromes
- Sarcoidosis and Beryllium Toxicity Research
- Cardiomyopathy and Myosin Studies
- Peptidase Inhibition and Analysis
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Parathyroid Disorders and Treatments
- Pharmaceutical studies and practices
- Pneumocystis jirovecii pneumonia detection and treatment
- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Cardiac Health and Mental Health
- Pain Management and Treatment
- Pancreatitis Pathology and Treatment
- Neuroendocrine Tumor Research Advances
- Chemotherapy-induced cardiotoxicity and mitigation
- Takotsubo Cardiomyopathy and Associated Phenomena
Hospital Universitario Puerta de Hierro Majadahonda
2012-2020
Medicines Evaluation Board
2008
Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous clinical syndrome multiple underlying causes. Wild-type transthyretin (TTR) amyloidosis (ATTRwt) an underdiagnosed cause of HFpEF that might benefit from new specific treatments. ATTRwt can be diagnosed non-invasively by 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid (99mTc-DPD) scintigraphy. We sought to determine the prevalence among elderly patients admitted due HFpEF. prospectively screened all consecutive ≥60...
Wild-type transthyretin amyloidosis (ATTRwt) is mostly considered a disease predominantly of elderly male, characterized by concentric LV hypertrophy, preserved LVEF, and low QRS voltages. We sought to describe the characteristics large cohort ATTRwt patients better define disease.Clinical findings consecutive diagnosed at 2 centres were reviewed. was histologically or non-invasively (LV hypertrophy ≥12 mm, intense cardiac uptake 99mTc-DPD scintigraphy AL exclusion). Mutations in TTR...
Objective: Cardiac amyloid infiltration can lead to systolic heart failure (HF) or conduction disorders (CD). Patients with transthyretin (ATTR) amyloidosis are particularly exposed. We sought determine the prevalence of ATTR and AL among patients >60 years admitted CD unexplained HF increased wall thickness. Materials Methods: studied 143 (57% males, 79 ± 9 years) (N = 28) requiring pacemaker implantation 115). In total, 139 (97%) (28 111 CD) underwent 99mTc-DPD scintigraphy detect ATTR,...