René R. W. J. van der Hulst

ORCID: 0000-0002-3904-118X
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About
Contact & Profiles
Research Areas
  • Reconstructive Surgery and Microvascular Techniques
  • Breast Implant and Reconstruction
  • Body Contouring and Surgery
  • Reconstructive Facial Surgery Techniques
  • Body Image and Dysmorphia Studies
  • Lymphatic System and Diseases
  • Breast Cancer Treatment Studies
  • Clinical Nutrition and Gastroenterology
  • Dermatologic Treatments and Research
  • Diet and metabolism studies
  • Surgical site infection prevention
  • Facial Rejuvenation and Surgery Techniques
  • Cancer survivorship and care
  • Wound Healing and Treatments
  • Bone fractures and treatments
  • Nutrition and Health in Aging
  • Mesenchymal stem cell research
  • Cardiac and Coronary Surgery Techniques
  • Orthopedic Surgery and Rehabilitation
  • Nerve Injury and Rehabilitation
  • Anatomy and Medical Technology
  • Sympathectomy and Hyperhidrosis Treatments
  • Surgical Simulation and Training
  • Cleft Lip and Palate Research
  • Craniofacial Disorders and Treatments

Maastricht University
2016-2025

Zuyderland Medisch Centrum
2018-2025

Maastricht University Medical Centre
2015-2024

Brigham and Women's Hospital
2019-2024

University Medical Center
2012-2023

University Hospital and Clinics
2022

Memorial Sloan Kettering Cancer Center
2021

John Radcliffe Hospital
2021

Spaarne Gasthuis
1999-2021

Eindhoven University of Technology
2021

Breast implants are among the most commonly used medical devices. Since 2008, number of women with breast diagnosed anaplastic large-cell lymphoma in (breast-ALCL) has increased, and several reports have suggested an association between risk breast-ALCL. However, relative absolute risks breast-ALCL still unknown, precluding evidence-based counseling about implants.To determine implants.Through population-based nationwide Dutch pathology registry we identified all patients primary non-Hodgkin...

10.1001/jamaoncol.2017.4510 article EN JAMA Oncology 2018-01-04

Abstract Advancements in reconstructive microsurgery have evolved into supermicrosurgery; connecting vessels with diameter between 0.3 and 0.8 mm for reconstruction of lymphatic flow vascularized tissue transplantation. Supermicrosurgery is limited by the precision dexterity surgeon’s hands. Robot assistance can help overcome these human limitations, thereby enabling a breakthrough supermicrosurgery. We report first-in-human study robot-assisted supermicrosurgery using dedicated...

10.1038/s41467-019-14188-w article EN cc-by Nature Communications 2020-02-11

Macrophages play a crucial role in all stages of cutaneous wound healing responses and dysregulation macrophage function can result derailed repair. The phenotype macrophages is influenced by the microenvironment evolves during from more pro-inflammatory (M1) profile early stages, to less inflammatory pro-healing (M2) later aim current study was investigate potential exogenous administration M2 promote an experimental mouse model injury. Bone marrow derived were stimulated in-vitro with IL-4...

10.1371/journal.pone.0102994 article EN cc-by PLoS ONE 2014-07-28

Metopic synostosis is thought to have an incidence of about 1 in 15,000 births. Traditionally, this makes it the third most frequent single-suture craniosynostosis, after scaphocephaly (1 4200-8500) and plagiocephaly 11,000). Our units have, independently from each other, noted a marked increase number metopic over recent years. This pan-European, retrospective epidemiological study on cases with born between January 1, 1997, 2006. was compared prevalence scaphocephaly, frequently seen...

10.1097/scs.0b013e31818436be article EN Journal of Craniofacial Surgery 2009-03-01

Background: It has been proposed that negative pressure wound therapy (NPWT) applied prophylactically to a closed incision may decrease the incidence of complications. Patients undergoing reduction mammaplasty are at risk complications such as delayed healing, infection, and dehiscence, bilateral nature surgery allows for within-patient randomized study evaluate incisional NPWT’s effect in reducing healing Methods: In this multicenter trial, 200 patients were treated with PICO Single-Use...

10.1097/gox.0000000000001560 article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2018-01-01

The number of breast cancer survivors continues to grow. Due refinements in operating techniques, autologous reconstruction has become part standard care. Impaired sensation remains a debilitating side effect with significant impact on the quality life. Microsurgical nerve coaptation sensory potential improve reconstructed breast. This study investigates improved life survivors.A retrospective cohort was performed Maastricht University Medical Center. Patients undergoing DIEP flap between...

10.1007/s10549-017-4547-3 article EN cc-by Breast Cancer Research and Treatment 2017-10-25

Current noninvasive tests to confirm the eradication of Helicobacter pylori must be performed 4 weeks or more after therapy is completed.To determine whether stool antigen test, a relatively new test for H. pylori, administered at various times correctly identifies persons with persistent infection.Prospective blinded study.Six clinical centers in United States and Europe.84 --infected patients undergoing endoscopy upper abdominal symptoms.At baseline on day 35 completion triple therapy, all...

10.7326/0003-4819-136-4-200202190-00007 article EN Annals of Internal Medicine 2002-02-19

Background and study aims: Cecal intubation is not achieved in 2 – 23 % of colonoscopies. The efforts made by physicians to visualize the remaining colon number missed significant lesions are unknown. This evaluates 1) reasons for incomplete colonoscopy, 2) rates complete colonic evaluation after 3) (pre-) malignant colonoscopy.

10.1055/s-0030-1255523 article EN Endoscopy 2010-07-28

Autologous fat transfer (AFT or grafting) has become an invaluable tool for the correction of disfiguring deformities after breast cancer surgery. However, clinical and animal studies have shown conflicting results regarding its oncologic safety.To determine whether exposure to AFT vs conventional reconstruction is associated with increased rates relapse in patients cancer.This matched cohort study involved retrospective medical record review identify all a local patient database receiving...

10.1001/jamasurg.2018.3744 article EN JAMA Surgery 2018-10-10

Robotic assistance in microsurgery could enhance human precision and dexterity to improve clinical outcomes. Because no robotic device has been designed primarily for microsurgery, the authors developed a dedicated microsurgical system. This preclinical study investigates whether anastomosis can be successfully completed on silicone vessels using prototype of this new system, compares outcomes robot-assisted versus conventional microsurgery.Three participants at different levels training 10...

10.1097/prs.0000000000004939 article EN Plastic & Reconstructive Surgery 2018-08-17

Background: The sensory recovery of the breast remains an undervalued aspect autologous reconstruction. aim this study was to evaluate effect nerve coaptation on following DIEP flap reconstruction and assess associations length follow-up timing Methods: A prospective comparative conducted all patients who underwent either innervated or noninnervated returned for between September 2015 July 2017. Nerve performed anterior cutaneous branch third intercostal nerve. Semmes-Weinstein monofilaments...

10.1097/prs.0000000000005802 article EN Plastic & Reconstructive Surgery 2019-07-26

Lymphaticovenous anastomosis, a supermicrosurgical technique, creates bypasses between the lymphatic and venous systems. The quality of lymphaticovenous anastomosis depends on surgeon's dexterity precision, is subject to imperfections caused by physiologic tremor human hand. A dedicated robot for microsurgery has been created overcome these limitations (MUSA, MicroSure, Eindhoven, Netherlands). This study describes 1-year clinical outcomes first-in-human trial robot-assisted manual in...

10.1097/prs.0000000000008670 article EN Plastic & Reconstructive Surgery 2021-12-21

Importance There is a need for new, less invasive breast reconstruction option patients who undergo mastectomy in their cancer treatment. Objective To investigate quality of life (QoL) among undergoing new technique, autologous fat transfer (AFT), compared with that implant-based (IBR). Design, Setting, and Participants The BREAST trial was randomized clinical conducted between November 2, 2015, October 31, 2021, performed 7 hospitals across the Netherlands. Follow-up 12 months. Referrals...

10.1001/jamasurg.2022.7625 article EN JAMA Surgery 2023-03-01
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