A5073710983- Hepatitis B Virus Studies
- Reproductive tract infections research
- Cancer Cells and Metastasis
- Hepatitis C virus research
- Cervical Cancer and HPV Research
- Melanoma and MAPK Pathways
- Viral Infections and Outbreaks Research
- Preterm Birth and Chorioamnionitis
- Wnt/β-catenin signaling in development and cancer
- Immune Response and Inflammation
- SARS-CoV-2 and COVID-19 Research
United States Food and Drug Administration
2022
Center for Biologics Evaluation and Research
2022
The Wistar Institute
2021
University of Pennsylvania
2019
The upregulation of the adaptor protein NUMB triggers melanocytic differentiation from multipotent skin stem cells, which share many properties with aggressive melanoma cells. Although acts as a tumor suppressor in various human cancer types, little is known about its role melanoma. In this study, we investigated progression and regulatory mechanism. Analysis Cancer Genome Atlas datasets revealed that high expression tissues correlates improved patient survival. Moreover, downregulated...
A hepatitis B vaccination (HepB) series with an initial dose of immune globulin (HBIG) is the recommended prophylaxis for infants born to mothers chronic virus (HBV) infection and HBV-exposed persons without known protection. The HepB HBIG are administered at different sites (limbs). Instances same site documented but impact on responses remains unanswered.Newborn adult BALB/c mice received one time zero alone or in sites, followed by 2 additional doses 3 10 weeks (newborn mice) 4 16 (adult...
Studies on Ebola virus disease (EVD) survivors and clinical studies (EBOV) vaccine candidates have pinpointed the importance of a strong antibody response in protection survival from EBOV infection. However, little is known about T cell responses to or vaccines. We used HLA-A*02:01 (HLA-A2) transgenic mice study HLA-A2-specific elicited following vaccination with glycoprotein (EBOV-GP) presented three different systems: (i) recombinant protein (rEBOV-GP), (ii) vesicular stomatitis...