- Pregnancy and preeclampsia studies
- Birth, Development, and Health
- Adipose Tissue and Metabolism
- Color perception and design
- Adipokines, Inflammation, and Metabolic Diseases
- Multisensory perception and integration
- Peroxisome Proliferator-Activated Receptors
- Reproductive System and Pregnancy
- Cancer, Lipids, and Metabolism
- Olfactory and Sensory Function Studies
- Retinoids in leukemia and cellular processes
- Vitamin D Research Studies
- Culinary Culture and Tourism
- Immune cells in cancer
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Plant Stress Responses and Tolerance
- Kruppel-like factors research
- Genetic and phenotypic traits in livestock
- Connective tissue disorders research
- Machine Learning in Bioinformatics
- Plant Molecular Biology Research
- Ruminant Nutrition and Digestive Physiology
- Antioxidant Activity and Oxidative Stress
- Cancer Risks and Factors
- Effects of Environmental Stressors on Livestock
Zhejiang University
2025
Soochow University
2023-2024
University of Colorado Denver
2018-2023
University of Colorado Anschutz Medical Campus
2023
Jilin Agricultural University
2018
University of Idaho
2013-2015
National Beef Cattle Industrial Technology System
2010
The functions of 1, 25-dihydroxyvitamin D (1, 25-(OH)2D3) in regulating adipogenesis, adipocyte differentiation and key adipogenic gene expression were studied 3T3-L1 preadipocytes. Five concentrations (0.01, 0.1, 10, 100nM) 25-(OH)2D3 lipid accumulation measured by Oil Red O staining genes quantified using quantitative real-time PCR. Adipogenic responses to determined on 6, 12 h, days 1-10 after induction adipogenesis a hormonal cocktail with or without 25-(OH)2D3. In response 100 nM), the...
Immunocompromised populations, including cancer patients, elderly individuals, and those with chronic diseases, are the primary targets of superbugs. Traditional vaccines less effective due to insufficient or impaired immune cells. Inspired by "vanguard" effect neutrophils (NE) during natural infection, this project leverages ability NE initiate NETosis program recruit monocytes DC cells, designing that can rapidly cells enhance response. The PLGA microsphere vaccine platform (MSV) a high...
Abstract Pregnancies complicated by severe, early-onset fetal growth restriction with abnormal Doppler velocimetry (FGRadv) have a sparse villous vascular tree secondary to impaired angiogenesis. As endothelial cell (EC) and stromal matrix interactions are key regulators of angiogenesis, we investigated the role placental on fetoplacental EC We developed novel model generating fibroblast (FB) cell-derived matrices (CDMs), allowing us interrogate placenta-specific human their effects found...
ABSTRACT Placentas from pregnancies complicated by severe early-onset fetal growth restriction (FGR) exhibit diminished vascular development mediated impaired angiogenesis, but underlying mechanisms remain unknown. In this study, we show that FGR endothelial cells demonstrate inherently reduced migratory capacity despite the presence of fibronectin, a matrix protein abundant in placental stroma displays abnormal organization placentas. Thus, hypothesized aberrant endothelial-fibronectin...
Pregnancies complicated by severe fetal growth restriction with abnormal umbilical artery Doppler velocimetry (FGRadv) are at substantial risk for adverse perinatal and long-term outcomes. Impaired angiogenesis of the placental vasculature in these pregnancies results a sparse, poorly branched vascular tree, which structurally contributes to abnormally elevated fetoplacental resistance that is clinically manifested absent or reversed indices. Previous studies have shown aryl hydrocarbon...
ABSTRACT Companies often change product packaging colors to drive innovation and boost sales. However, these changes may violate expectations, resulting in inconsistent associations between new original labels. It remains unclear whether consumers can learn associations. This study delved into the effect of expectation violation on consumer learning color–label (flavor/brand) by varying degree (adjacent complementary) To assess associative strength, we compared effects under strong...
To investigate the function of nutrient molecules (1, 25‐dihydroxyvitamin D 25‐(OH) 2 3 ) and retinoic acid (RA)) in regulation adipogenesis, adipocyte differentiation key adipogenic gene expression were studied 3T3‐L1 preadipocytes. Lipid accumulation was measured by Oil Red O staining genes quantified using quantitative real‐time PCR. Adipogenic responses to 1, or RA determined on days 2–10 after induction adipogenesis with traditional hormonal cocktail ± RA. In response (10 −7 , 10 −8 −9...
Severe fetal growth restriction (FGR) is characterized by increased placental vascular resistance resulting from aberrant angiogenesis. Interactions between endothelial cells (ECs) and the extracellular matrix (ECM) are critical to complex process of We have previously found that stromal abnormalities contribute impaired angiogenesis in severe FGR. The objective this research better characterize effect individual ECM proteins on angiogenic properties setting ECs were isolated human...
The spike in obesity worldwide has prompted a slew of nutritional information policies and healthy eating nudges that aim to improve people's diets. Of all the strategies have proposed, changing consumers’ perceptions evaluations food through aesthetic plating may be an untested, yet effective low-cost approach encourage globally. present study explored how different aesthetics types affect high low-calorie foods by Eastern Western consumers. Valid data were collected from 181 Chinese...