A5101477932- Adipose Tissue and Metabolism
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Liver Disease Diagnosis and Treatment
- Cytokine Signaling Pathways and Interactions
Immanuel Kant Baltic Federal University
2021
108 Military Central Hospital
2021
Interleukin (IL)-6 family cytokines act through a receptor complex with gp130 subunits. IL-6 is pleiotropic cytokine that regulates inflammation and liver regeneration. Mitochondria are the first to respond stress adapt their dynamics in conditions of damage. In this regard, study aimed investigate role (sIL-6Ra, gp130/sIL-6Rb, IL-11) regulation mitochondrial obese patients assess contribution these pathogenesis type 2 diabetes mellitus (T2DM). We studied 134 without T2DM 41 healthy donors....
Interactions between receptors and ligands of the tumor necrosis factor superfamily (TNFSF) provide costimulatory signals that control survival, proliferation, differentiation, effector function immune cells. All components TNF are associated with NF-kB functions not limited to cell death may promote survival in face adipose tissue inflammation obesity. Inflammation dysfunction mitochondria is a key insulin resistance The aim study was analyze relationship soluble forms blood plasma...
Interactions between receptors and ligands of the tumor necrosis factor superfamily (TNFSF) provide costimulatory signals that control survival, proliferation, differentiation, effector function immune cells. All components TNF are associated with NF-kB functions not limited to cell death may promote survival in face adipose tissue inflammation obesity. Inflammation pro-inflammatory dysfunction mitochondria key factors insulin resistance The aim study was analyze relationship soluble forms...