Yu Chen

ORCID: 0000-0002-4067-9172
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About
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Research Areas
  • Phytochemical Studies and Bioactivities
  • Phytochemistry and Bioactive Compounds
  • Garlic and Onion Studies
  • Metabolomics and Mass Spectrometry Studies
  • Natural product bioactivities and synthesis
  • Metabolism, Diabetes, and Cancer
  • Synthesis of Organic Compounds
  • Phytochemistry and Biological Activities
  • Metabolism and Genetic Disorders
  • Bioactive natural compounds
  • Effects and risks of endocrine disrupting chemicals
  • Cellular transport and secretion
  • Pancreatic function and diabetes
  • Synthesis and Biological Activity
  • Skin Protection and Aging
  • Diet and metabolism studies
  • Plant-derived Lignans Synthesis and Bioactivity
  • Nuts composition and effects
  • Natural Products and Biological Research
  • Plant chemical constituents analysis

Southwest Medical University
2020

University of Chinese Academy of Sciences
2015-2019

Xinjiang Technical Institute of Physics & Chemistry
2019

Chinese Academy of Sciences
2007-2017

Kunming Institute of Botany
2015-2017

South Central Minzu University
2009-2014

Institute of Biophysics
2007

Huazhong University of Science and Technology
2007

Abstract A new dimeric lignan, named biplanispine ( 1 ) which represents the first example of a 2,6‐diaryl‐3,7‐dioxabicyclo[3.3.0]octane skeleton from Rutaceae plant, together with 13 known lignans 2 – 14 , was isolated bark Zanthoxylum planispinum. Their structures were elucidated by spectroscopic methods, especially 2D‐NMR techniques. All compounds evaluated for their antibacterial activities disc diffusion method. Compounds 7 and 9 showed interesting at 200 μg/disc; they as effective...

10.1002/hlca.200900055 article EN Helvetica Chimica Acta 2009-08-01

Glycoborinine (GB), a natural carbazole alkaloid isolated from Glycosmis pentaphylla, has been shown to be potential molecule against cancer cells. In this study, the cell-signaling pathway of its anti-tumor activity was investigated. MTT assay result showed that GB inhibited HepG2 cell proliferation in dose- and time-dependent manner 50% inhibiting concentration (IC50) GB-induced death 39.7 μM for period 48 h. apoptosis confirmed by Hochest 33258 staining PI staining. The level reactive...

10.1080/10286020.2014.918961 article EN Journal of Asian Natural Products Research 2014-06-16

Phytochemical investigation on the whole plants of Ypsilandra yunnanensis was carried out for first time and led to isolation five new cholestanol glycosides, ypsiyunnosides A–E (1–5), one known analogue. Their structures were determined mainly by detailed spectroscopic analysis, including extensive 1D 2D NMR, MS UV, as well chemical methods. Among them, compound 1 possessed a rare 6/6/6/5/5 fused-rings sketelon, which identified...

10.1007/s13659-016-0098-2 article EN cc-by Natural Products and Bioprospecting 2016-04-20

E-mail: yanggz888@126.comReceived July 15, 2013, Accepted December 9, 2013Key Words : Triterpenoid saponins, Lardizabalaceae, Stauntonia chinensisStauntonia chinensis DC. (Lardizabalaceae), an evergreenherb growing in southern China, commonly known as “YeMu Gua”, has been used a traditional Chinese medicine,especially for its anti-inflammatory and analgesic effects.

10.5012/bkcs.2014.35.4.1212 article EN Bulletin of the Korean Chemical Society 2014-04-20

Abstract Background Longan is the fruit of Dimocarpus longan Lour. and arillus has been used in traditional Chinese medicine for thousands years possessing various health benefits. However, excessive intake found daily life to cause “ shanghuo ” syndrome. Shanghuo linked increased disease susceptibility. The present study thus aimed investigate toxicological outcomes after excess treatment. Methods extract at a normal dosage 4 g/kg two dosages 8 16 was orally administered C57BL/6J mice 2...

10.21203/rs.3.rs-117893/v1 preprint EN cc-by Research Square (Research Square) 2020-12-03
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