A5100710938- Spectroscopy Techniques in Biomedical and Chemical Research
- Energetic Materials and Combustion
- Thermal and Kinetic Analysis
- Plant Toxicity and Pharmacological Properties
- Spectroscopy and Chemometric Analyses
- Genetic Mapping and Diversity in Plants and Animals
- Drug-Induced Hepatotoxicity and Protection
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Crystallography and molecular interactions
- Poisoning and overdose treatments
- Genetic and phenotypic traits in livestock
- Advanced biosensing and bioanalysis techniques
- Metabolomics and Mass Spectrometry Studies
- Nanoparticle-Based Drug Delivery
- Plant tissue culture and regeneration
- Nanoparticles: synthesis and applications
- Molecular Biology Techniques and Applications
- Cancer-related molecular mechanisms research
- Plant Gene Expression Analysis
- Chemical Thermodynamics and Molecular Structure
- Viral Infectious Diseases and Gene Expression in Insects
- Natural Compounds in Disease Treatment
- Traditional Chinese Medicine Analysis
- Glaucoma and retinal disorders
City College of New York
2017-2024
Fujian Agriculture and Forestry University
2024
Health Commission of Anhui Province
2024
Affiliated Hospital of Youjiang Medical University for Nationalities
2023-2024
Nanjing Medical University
2022-2023
Weatherford College
2023
Chinese University of Hong Kong
2013-2023
Suzhou Municipal Hospital
2022-2023
Beijing Academy of Agricultural and Forestry Sciences
2022-2023
Zhejiang University of Finance and Economics
2023
Cellular fate of nanoparticles is vital to application cell imaging, bio-sensing, drug delivery, suppression resistance, gene delivery and cytotoxicity analysis. However, the current studies on cellular have been controversial due complications interplay between many possible factors. By well-controlled experiments, we demonstrated unambiguously that morphology independently determined their fate. We found with sharp shapes, regardless surface chemistry, size, or composition, could pierce...
Drug release simultaneously with carrier decomposition has been demonstrated in SiO2-drug composite nanoparticles. By creating a radial drug concentration gradient the nanoparticle, controllable of is primarily driven by diffusion. Escape molecules then triggers SiO2 decomposition, which starts from center nanoparticle and eventually leads to its complete fragmentation. The small size final fragments enables their easy excretion via renal systems. Together known biocompatibility SiO2,...
Abstract To investigate whether industrial robots have improved the ecological environment, this study integrated adoption of robot technology and pollution abatement into Melitz's heterogeneous firm model. This showed that using in production can lower firms' intensity by increasing their investments, reduction effect is greater for higher polluting firms those subject to weaker local environmental regulations. These theoretical expectations were then confirmed through a series empirical...
Glioma is one of the most refractory types brain tumor. Accurate tumor boundary identification and complete resection are essential for glioma removal during surgery. We present a method based on visible resonance Raman (VRR) spectroscopy to identify margins grades. A set diagnostic spectral biomarkers features presented tissue composition changes revealed by VRR. The spectra include molecular vibrational fingerprints carotenoids, tryptophan, amide I/II/III, proteins, lipids. These basic...
Tibial cortex transverse distraction is a surgical method for treating severe diabetic foot ulcers (DFUs), but the underlying mechanism unclear. We show that antioxidant proteins and small extracellular vesicles (sEVs) with multiple-tissue regenerative potential are released during bone transport (BT) in humans rats. These accumulate wounds enriched microRNAs (miRNAs) (e.g., miR-494-3p) have high activities improve circulation of ischemic lower limbs while also promoting neovascularization,...
Background: Longan is the fruit of Dimocarpus longan Lour. and arillus has long been used in traditional Chinese medicine possessing various health benefits. However, excessive intake found daily life to cause “ shanghuo ” syndrome. Shanghuo linked increased disease susceptibility. The present study thus aimed investigate toxicological outcomes after treatment. Methods: extract at a normal dosage 4 g/kg two excess dosages 8 16 was orally administered C57BL/6J mice for weeks or with...
Abstract The aberrant regulation of PD‐L1 in tumor cells remains poorly understood. Here, the authors systematically investigate endosomal trafficking plasma membrane cells. They show that is continuously internalized, and then trafficked from early endosomes to multivesicular bodies/late endosomes, recycling lysosomes, and/or extracellular vesicles (EVs). This constitutive endocytic Rab5‐ clathrin‐dependent. Triazine compound 6J1 blocks induces its accumulation by activating Rab5. also...
Vegetable oil is an important part of the human diet and has multiple industrial uses. The rapid increase in vegetable consumption necessitated development viable methods for optimizing content plants. key genes regulating biosynthesis maize grain remain mostly uncharacterized. In this study, by analyzing contents performing bulked segregant RNA sequencing mapping analyses, we determined that su1 sh2-R mediate shrinkage ultra-high-oil grains contribute to content. Functional kompetitive...
4,4′-Azo-bis(1,2,4-triazolone) (<bold>ZTO</bold>) based salts from alkaline (Li<sup>+</sup>, K<sup>+</sup>, Na<sup>+</sup>, and Cs<sup>+</sup>), earth metal (Mg<sup>2+</sup>, Ca<sup>2+</sup>, Sr<sup>2+</sup>, Ba<sup>2+</sup>) hydrazinium salt were synthesized in a simple, straightforward manner characterized by IR NMR spectroscopy, elemental analysis.
In depth studies of quantitative trait loci (QTL) can provide insights to the genetic architectures complex traits. A major effect QTL at distal end chicken chromosome 1 has been associated with growth traits in multiple populations. This locus was fine-mapped a fifteen-generation advanced intercross population including 1119 birds and explored further detail using 222 sequenced genomes from 10 high/low body weight stocks. We detected this that, total, contributed 14.4% variance for growth....
Multidrug resistance (MDR) mediated by ATP binding cassette subfamily B member 1 (ABCB1) is significantly hindering effective cancer chemotherapy. However, currently, no ABCB1-inhibitory drugs have been approved to treat MDR clinically, mainly due the inhibitor specificity, toxicity, and drug interactions. Here, we reported that three polyoxypregnanes (POPs) as most abundant constituents of Marsdenia tenacissima (M. tenacissima) were novel ABCB1-modulatory pro-drugs, which underwent...
Maintenance of appropriate levels fecundity is critical for efficient sheep production. Opportunities to increase litter size include identifying single gene mutations with major effects on ovulation rate and size. Whole-genome sequencing (WGS) data 89 Chinese domestic from nine different geographical locations ten Australian were analyzed detect new polymorphisms affecting Comparative genomic analysis contrasting detected a novel set candidate genes. Two SNPs, g.71874104G>A g.71833755T>C,...