A5017559121- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Meningioma and schwannoma management
- Liver Diseases and Immunity
- Neurofibromatosis and Schwannoma Cases
- Pancreatitis Pathology and Treatment
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Pituitary Gland Disorders and Treatments
- Adrenal and Paraganglionic Tumors
- Ocular Oncology and Treatments
- Cancer and Skin Lesions
- Diet, Metabolism, and Disease
- Hematopoietic Stem Cell Transplantation
- Head and Neck Surgical Oncology
- Ophthalmology and Eye Disorders
- Hepatitis Viruses Studies and Epidemiology
- Liver physiology and pathology
- Glioma Diagnosis and Treatment
- IgG4-Related and Inflammatory Diseases
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Teratomas and Epidermoid Cysts
- Peroxisome Proliferator-Activated Receptors
- Gallbladder and Bile Duct Disorders
Ankara University
2013-2023
Turkish Thoracic Society
2017
Turkish Aerospace Industries (Turkey)
2012
Hippocration General Hospital
2009
Kochi Medical School Hospital
2009
Mie University
2009
Gazi University
1998-2007
Wageningen University & Research
2007
HeidelbergCement (Sweden)
2007
Türkiye Yüksek İhtisas Hastanesi
2005
Summary. Chronic delta hepatitis is the most severe form of chronic viral for which interferon (IFN) only available treatment. In 39 patients (25 were treatment‐naïve, 14 had previously used IFN), efficacy 1‐year treatment with IFN (9 MU, t.i.w.) or lamivudine (LAM; 100 mg, q.d.) alone was compared and LAM combination (2 months to be followed by treatment). monotherapy given treatment‐naïve patients. both previous users, end virological biochemical responses similar IFN–LAM superior ( P <...
Summary Background Currently, although only a few therapies normalize the liver test abnormalities with/without improving histology, no pharmacologic therapy has proved to be effective for treatment of non‐alcoholic steatohepatitis. Aim To investigate role insulin sensitizers in individuals with steatohepatitis (NASH). Methods A total 74 NASH (male/female, 44/30; mean age, 47.2 ± 9.0 years) were enrolled. Participants divided into two distinct groups: group 1 ( n = 25) participants...
Abstract Background: Insulin resistance (IR) is commonly associated with non‐alcoholic steatohepatitis (NASH). Peroxisome proliferator‐activated receptor‐α (PPAR‐α) may also play a role in the pathogenesis of NASH. A pivotal NASH depends on hypothesis increased oxidative stress. The aim our study was to evaluate effects supplemental oral vitamin E, potent antioxidant, liver functions, PPAR‐α expression and IR patients Methods: Nine biopsy‐proven were given E 800 mg daily for 24 weeks. Liver...
Background and Goals The aim of this cohort study was to determine the characteristics clinical outcome 170 patients with drug-induced liver injury (DILI) in a single center. Study Between January 2001 June 2007, total individuals who were diagnosed DILI retrospectively analyzed. median follow-up period 110.0 days. Results During period, 5471 new assessed for test abnormalities. Of those, (3.1%) fulfilled criteria DILI. A 83 different drugs considered be related hepatotoxicity; drug...
Purpose: To evaluate the presentation patterns and results of management retinoblastoma at a tertiary care center in Ankara, Turkey, with special emphasis on globe conservation rate unilateral bilateral intraocular retinoblastoma. Methods: Patients were grouped according to International Classification Retinoblastoma. For retinoblastoma, group E some D eyes underwent primary enucleation. Secondary enucleation was performed after failure chemoreduction, focal treatments, external beam...
Summary. To determine whether combination treatment of HBeAg(−) chronic hepatitis B is beneficial we studied 78 patients with HBeAg(−), HBV DNA‐positive who were randomized to lamivudine, 100 mg, qd, for 12 months or lamivudine–interferon (9 MU, t.i.w.) in combination. In the arm, 2 lamivudine preceded 10 treatment. Biochemical, virologic and histologic responses assessed at end treatment, after six a median 27 drug‐free follow‐up (short‐ long‐term follow‐up, respectively). Virologic...
To report a case of possible levofloxacin-induced acute fulminant hepatic failure.An unconscious 55-year-old woman was hospitalized with the diagnosis encephalopathy. The patient had received levofloxacin 500 mg daily for 10 days because an upper respiratory infection. Her past medical history revealed hepatitis B surface antigen positivity as asymptomatic virus carrier years. After hospitalization, treatment included plasmapheresis and supportive care. patient's consciousness improved on...
We report a rare case of calcifying pseudoneoplasm in the foramen magnum. A large variety tumors can be found magnum; meningiomas, neurofibromas, chordomas, chondrosarcomas and metastases are among those that have been reported. Based on histopathological structure tumor, radical excision or, with good behavioral pattern, only decompressive debulking applied, an effort to avoid unnecessary morbidities. Thus, it is important know nature tumor before planning surgery.A 53-year-old man 1-year...
The aim of this study was to evaluate the efficacy pegylated interferon (PEG-IFN) alfa-2b for short (one year) and long (two years) terms treatment chronic hepatitis D.Eighteen patients with D were administered PEG-IFN 1.5μg/kg twice weekly 1 month, after which they randomly assigned (2:1) receive 1.5μg/kg/wk an additional 23 months (n=11; group 1) or 11 (n=7; 2). All followed-up 6 completing therapy.In 1, there no significant difference between HDV-RNA ALT levels at follow-up compared...
Gallbladder cancer is a rare neoplasm. We report our experience with gallbladder that was incidentally diagnosed during or after laparoscopic cholecystectomy performed for gallstone disease.This study included all cholecystectomies due to disease undertaken from May 1999 June 2010. Exclusion criteria were suspicion of malignancy and/or existence polyps detected ultrasonography preoperatively. Patients recorded, and the clinical demographic characteristics these patients reviewed.Of 5,382 in...
Liver biopsy to assess fibrosis is invasive and prone sampling error. While algorithms of serum markers predict stage have been described for chronic hepatitis C, these cannot be applied equally well B.We therefore determined 9 markers, liver biochemical tests ultrasound parameters in 109 consecutive adult patients with B D. All had compensated disease. Using the METAVIR score, advanced disease was defined as ≥F2, active inflammation grade ≥A2. A gold standard created considering...
The presence of microchimerism in transplanted tissues is well defined; however, the timeframe appearance and disappearance engraftment liver allograft unknown. aims this study were to analyze for "recipient-derived cells" sex-mismatched individuals after transplantation, comparing frequency cell repopulation" early versus late transplant biopsies evaluate relationship between severity graft injury.Paraffin-embedded biopsy samples 18 recipients reviewed. Sixteen them obtained from with...
Purpose: To evaluate the role of optic nerve biopsy in diagnosis and management sheath tumors.