A5038906875- Vitamin D Research Studies
- Vitamin C and Antioxidants Research
- Thyroid Cancer Diagnosis and Treatment
- Chemotherapy-induced cardiotoxicity and mitigation
- Organ Transplantation Techniques and Outcomes
- Cancer-related cognitive impairment studies
- Chemotherapy-induced organ toxicity mitigation
- Circadian rhythm and melatonin
- Pharmacological Effects of Natural Compounds
- Renal Transplantation Outcomes and Treatments
- Pomegranate: compositions and health benefits
- Natural product bioactivities and synthesis
- Liver physiology and pathology
- Cancer Immunotherapy and Biomarkers
- Educational Methods and Analysis
- Synthesis of β-Lactam Compounds
- Head and Neck Anomalies
- Cancer and Skin Lesions
- Management of metastatic bone disease
- Bioactive Compounds in Plants
- Celiac Disease Research and Management
- Lung Cancer Research Studies
- Diet, Metabolism, and Disease
- Inflammatory mediators and NSAID effects
- Microscopic Colitis
Pamukkale University
2021-2025
Dokuz Eylül University
2013-2022
Süleyman Demirel University
2019-2022
Inonu University
2022
Ordu University
2022
Izmir Bozyaka Eğitim ve Araştırma Hastanesi
2021
Izmir University
2021
Sağlık Bilimleri Üniversitesi
2020
Kırıkkale University
2012
Ankara University
2004-2005
Background: Favipiravir (FPV), an effective antiviral agent, is a drug used to treat influenza and COVID-19 by inhibiting the RNA-dependent RNA polymerase (RdRp) of viruses. FPV has potential increase oxidative stress organ damage. The purpose this study was demonstrate inflammation caused in liver kidneys rats, as well investigate curative effects vitamin C (VitC).Methods: A total 40 Sprague-Dawley male rats were randomly equally divided into following five groups: 1st; Control, 2nd; = 20...
High fructose corn syrup (HFCS) has been shown to cause cardiovascular toxicity via oxidative stress and inflammation. The aim of this study is demonstrate the protective effects melatonin (MLT) against HFCS-induced endothelial cardiac dysfunction Thirty-two Sprague Dawley male rats were distributed into three groups as control, HFCS, HFCS + MLT. form F55 was prepared 20% solution given through drinking water for 10 weeks, MLT administrated mg/kg/day orally last 6 weeks in addition F55....
Purpose: The immune system is the source of inflammatory, persistent skin condition known as psoriasis. Despite recent major advancements in pathology psoriasis, no bibliometric investigation associating TNF-Alpha polymorphisms to psoriasis has been conducted. objective this study was better understand development trend and boundaries area by using bibliometrics assess focal point research overview Polymorphisms Psoriasis. Methods: Web Science database searched on March 26, 2024, with terms...
Thioacetamide (TAA) is an organosulfur, white crystalline compound having liver injury. However, it shows toxic effects on many organs. The reverts the oxidative stress created by TAA heart and kidney, decreased lipid peroxide peroxidation back with antioxidant-properties nerolidol (NRL). This study hypothesized that NRL treatment a potential ameliorate nephrotoxicity cardiotoxicity caused TAA.Thirty-two Wistar Albino male rats (3-4 months old 280-300 g in weight) were divided into four...
Abstract The aim of the present study was to measure plasma uric acid (UA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSH‐Px) xanthine oxidase (XO) activities evaluate relationship between these parameters severity pre‐eclampsia. Twenty‐five pre‐eclamptic, 15 healthy pregnant non‐pregnant women were enrolled in this study. Increased mean XO activity found be higher both pre‐eclampsia groups than group. Plasma UA highest severe group among groups. SOD GSH‐Px significantly...
The presence of microchimerism in transplanted tissues is well defined; however, the timeframe appearance and disappearance engraftment liver allograft unknown. aims this study were to analyze for "recipient-derived cells" sex-mismatched individuals after transplantation, comparing frequency cell repopulation" early versus late transplant biopsies evaluate relationship between severity graft injury.Paraffin-embedded biopsy samples 18 recipients reviewed. Sixteen them obtained from with...
To investigate the histological and biochemical neuroprotective effects of secukinumab (SEC) on cerebral ischemia-reperfusion (IR) injury in Sprague-Dawley male rats.A total 28 rats were randomly equally divided into following four groups: Sham, SEC, IR, IR+SEC groups. Bilateral common carotid arteries simultaneously separated blocked for 15 minutes using two vascular mini clips IR The surgical procedure was similarly repeated Sham SEC groups, but not clipped. Secukinumab administered...
Aim: Gastric ulcers are the most common gastrointestinal disease, due to several factors in industrialized world. They may also occur after many pharmacological agents, combined with gastroprotective agents such as proton pump inhibitors (PPI) or anti-acids, used a preferred approach maintaining health. Unexpected adverse effects these combinations make natural products an important alternative option. Methods: Therefore, main aim of this study is investigate one compound, Tarantula cubensis...
The present study aimed to investigate the protective role of capsaicin in a rat model 2,3,7,8-tetracholorodibenzo-p-dioxin (TCDD)-induced toxicity. Exposure TCDD which is an environmental toxicant causes severe toxic effects animal and human tissues. Therefore, potential effect TCDD-induced organ damage was investigated rats by measuring thiobarbituric acid reactive substances (TBARS) level, superoxide dismutase (SOD) activity, glutathione (GSH) level heart, liver, kidney tissues for...
Abstract The present study investigates the effects of resveratrol (RSV) on brain and liver tissues in rats with pembrolizumab (PEMB)‐induced toxicity. Obtained for were 28 male Sprague‐Dawley (3–4 months old) which divided into four groups: Group 1: Control. 2: Administered PEMB at 5 mg/kg/day i.p. a week. 3: RSV orally dose 20 30 days by gavage. 4: RSV, respectively, days. results this revealed that leads to significant increase thiobarbituric acid reactive substance (TBARS) levels...
Monkeypox is a zoonotic viral infection that was first identified in humans 1970 the Democratic Republic of Congo. The cases seen again early May 2022 have reached 78.000 as today. On July 23, 2022, World Health Organization decided monkeypox outbreak represents public health emergency. For diagnosis and effective treatment monkeypox, inter-individual transmission routes, disease symptoms, factors affecting course disease, presence another infection, prognosis, pharmacological agents used...
The current structure–activity relationship of profens (i.e., 2-arylpropionic acid derivatives, a class non-steroidal anti-inflammatory drugs) discusses the importance α-monomethyl substitution on these compounds, since activities obtained through their corresponding arylacetic derivatives α-demethylated derivatives) or α,α-dimethyl-substituted compounds are less than what is observed for parent profens. Unfortunately, this implies generalization in relationships such way that...
Chemical effects on the Kß/Kα X-ray intensity ratios for some first-row transition element compounds were studied experimentally and calculated.The vacancies in K shell created by 59.5 keV r rays from an 2 4 1 A m radioactive source characteristic radiation sample was measured using Si(Li) Ge(Li) detectors.The calculations carried out Brunner's model.The calculated relative Kß/K α are good agreement with present previously published experimental data.
Favipiravir is a nucleoside analogue antiviral drug and inhibits the replication of many RNA viruses, especially influenza viruses. has also been used to treat patients with mild moderate COVID-19 disease. However, various side effects, including neurological have reported related use favipiravir. Therefore, in this study, we aimed investigate possible effects favipiravir alone or combination vitamin C on aged rats' brain tissue mechanisms these effects. A total 30 rats study were randomly...
To investigate the postoperative analgesic effects of epidural tramadol infiltration. Tramadol is a weak opioid that has local anesthetic and antiinflammatory properties. Materials methods: Sixty patients American Society Anesthesiologists class I or II undergoing lumbar microdiscectomy with general anesthesia were included in study. The induction was performed propofol (2-2.5 mg kg^{-1}, rocuronium bromide (0.5 kg^{-1}), fentanyl (1 µg kg^{-1}). A sevoflurane N_2O/O_2 (FiO_2 = 35%) mixture...
Background. The aims of this study were to determine the presence trefoil factor family-3 (TFF3) expression in biliary epithelial cells (BECs) chronic graft-versus-host disease (cGVHD) liver after allogeneic hematopoietic cell transplantation, compare such diseases (CLD) with/without predominantly disease, and assess effect bile duct injury on degree TFF3 BECs cGVHD. Methods. A total 82 paraffin-embedded biopsy samples reviewed. These basically divided into two distinct groups according...