A5021798810- Plant biochemistry and biosynthesis
- Adipose Tissue and Metabolism
- Cardiovascular Disease and Adiposity
- Plant Gene Expression Analysis
- Barrier Structure and Function Studies
- Connexins and lens biology
- Plant Molecular Biology Research
- Fungal Biology and Applications
- Photosynthetic Processes and Mechanisms
- Neuroinflammation and Neurodegeneration Mechanisms
- Plant-Microbe Interactions and Immunity
- Fungal Plant Pathogen Control
- Plant tissue culture and regeneration
- Muscle metabolism and nutrition
- Plant Genetic and Mutation Studies
- Phytochemicals and Antioxidant Activities
- Light effects on plants
- Protein Interaction Studies and Fluorescence Analysis
- Lipid metabolism and biosynthesis
- RNA Research and Splicing
- Nerve injury and regeneration
- Antioxidant Activity and Oxidative Stress
- Inflammatory Biomarkers in Disease Prognosis
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024-2025
Chongqing Medical University
2017-2025
Jilin Agricultural University
2021-2025
Guizhou University
2024-2025
Sichuan Agricultural University
2023-2025
Tea Research Institute
2025
Henan Agricultural University
2025
Henan University of Science and Technology
2023-2024
Chinese Institute for Brain Research
2023-2024
Sichuan University
2023-2024
BACKGROUND: The adult mammalian heart is incapable of regeneration, whereas a transient regenerative capacity maintained in the neonatal heart, primarily through proliferation preexisting cardiomyocytes. Neonatal regeneration after myocardial injury accompanied by an expansion cardiac fibroblasts and compositional changes extracellular matrix. Whether how these influence cardiomyocyte remains to be investigated. METHODS: We used apical resection infarction surgical models mice investigate...
In this study, the hepatoprotective effects of apple polyphenols (AP, Appjfnol) against CCl(4)-induced acute liver damage in Kunming mice as well possible mechanisms were investigated. Mice treated with AP (200, 400, and 800 mg/kg, ig) for seven consecutive days prior to administration CCl(4) (0.1%, intraperitoneally). The serum levels alanine aminotransferase (ALT) aspartate (AST), malondialdehyde (MDA), superoxide dismutase (SOD), reduced glutathione (GSH) concentrations hepatic...
Chokecherry (Padus virginiana L.) is an important landscaping tree with high ornamental value because of its colorful purplish-red leaves (PRL). The quantifications anthocyanins and the mechanisms leaf color change in this species remain unknown. potential biosynthetic regulatory accumulation patterns P. that determine three colors were investigated by combined analysis transcriptome metabolome. difference chlorophyll, carotenoid anthocyanin content correlated formation color. Using...
Reactive oxygen species (ROS) act as a group of signaling molecules in rice functioning regulation development and stress responses. Respiratory burst oxidase homologues (Rbohs) are key enzymes generation ROS. However, the role nine Rboh family members was not fully understood multiple disease resistance yield traits. In this study, we constructed mutants each genes detected their requirement Our results revealed that mutations five (RbohA, RbohB, RbohE, RbohH, RbohI) lead to compromised...
The natural product paeonol is a rich and sustainable bioresource, its derivatives have various unique biological efficacy. As well known, Schiff bases are class of organic compounds with wide range activities, including anti-fungal, insecticidal, anti-viral, nematicidal.
Abstract Lymphocyte subsets are the most intuitive expression of body’s immune ability, and lymphocyte-to-monocyte ratio (LMR) also clearly reflect degree chronic inflammation activity. The purpose this study is to investigate their predictive value lymphocyte LMR neoadjuvant therapy (NAT) efficacy in breast cancer patients. In study, were compared between patients (n = 70) benign tumor female populations 48). Breast treated with NAT, chemotherapy response was evaluated using established...
Perirenal adipose tissue (PRAT) is a unique visceral depot that contains mixture of brown and white adipocytes. The origin plasticity such cellular heterogeneity remains unknown. Here, we combine single-nucleus RNA sequencing with genetic lineage tracing to reveal the existence distinct subpopulation Ucp1 - & Cidea + adipocytes arises from brown-to-white conversion during postnatal life in periureter region mouse PRAT. Cold exposure restores expression thermogenic phenotype this...
The NAC (NAM, ATAF and CUC) gene family plays a crucial role in the transcriptional regulation of various biological processes has been identified characterized multiple plant species. However, genome-wide identification this not implemented Juglans mandshurica, specific functions these genes development fruits remain unknown. In study, we performed functional analysis during fruit total 114 JmNAC J. mandshurica genome. Chromosomal location revealed that were unevenly distributed 16...
The C-Repeat Binding Factor (CBF) gene family has been identified and characterized in multiple plant species, it plays a crucial role responding to low temperatures. Presently, only few studies on tree species demonstrate the mechanisms potential functions of CBFs associated with cold resistance, while our study is novel report multi-aspect differences among three compared previous studies. In this study, genome-wide identification analysis CBF Acer truncatum, pseudosieboldianum, yangbiense...
Drought stress is one of the major adversity stresses affecting soybean (Glycine max [L.] Merr.) yield. Late embryogenesis abundant protein (LEA protein) a large family proteins widely distributed in various types organisms, and this class plays an important role protecting proteins, membrane lipids, lipids inside cell. The GmPM35 gene member LEA_6 subfamily. expression was significantly increased after drought soybeans. A subcellular localization assay confirmed that acts on cell membrane....
Developing cost-effective electrocatalysts for efficient seawater splitting requires a fundamental understanding of the oxygen evolution reaction (OER) mechanism. Herein, iron-doped nickel phosphide (Fe-Ni2P) is synthesized via hydrothermal-impregnation-phosphidation strategy to investigate role Fe incorporation in modulating electronic structure and OER pathways. Mechanistic investigations demonstrate that doping triggers shift from adsorbate mechanism (AEM) lattice oxygen-mediated (LOM)...
WRKY transcription factors constitute one of the largest gene families in plants and are involved many biological processes, including growth development, physiological metabolism, stress response. In earlier studies, family proteins has been extensively studied analyzed plant species. However, information on Acer truncatum not reported. this study, we conducted genome-wide identification analysis A. truncatum, 54 genes were unevenly located all 13 chromosomes highest number was found 5....
Juglans mandshurica has strong freezing resistance, surviving temperatures as low -40 °C, making it an important freeze tolerant germplasm resource of the genus Juglans. APETALA2/ethylene responsive factor (AP2/ERF) is a plant-specific superfamily transcription factors that regulates plant development, growth, and response to biotic abiotic stress. In this study, phylogenetic analysis was used identify 184 AP2/ERF genes in J. genome, which were classified into five subfamilies (JmAP2, JmRAV,...
Abstract Objective To explore the immune status and chronic inflammation of breast cancer patients, this study aims to analyze diagnostic value peripheral blood lymphocyte subsets (CD3 + T, CD4 CD8 CD3 − CD19 B, NK cells) lymphocyte-to-monocyte ratio (LMR) for cancer. Furthermore, it seeks examine correlation between these LMR with clinicopathological features. Methods A total 100 patients were selected as experimental group, while 55 benign diseases included in control group. Statistical...
Abstract We previously reported that three point mutations in SASH 1 and mutated promote melanocyte migration dyschromatosis universalis hereditaria ( DUH ) a novel p53/ POMC /Gαs/ autoregulatory positive feedback loop is regulated by to induce pathological hyperpigmentation phenotype. However, the underlying mechanism of molecular regulation cause this disorder still remains unclear. In study, we aimed investigate undergirding disorder. Our results revealed binds with MAP 2K2 induced p53‐ ‐...
With-no-lysine (K) kinase-4 (WNK4) is a serine/threonine kinase that plays an essential role in the regulation of fluid and electrolyte homeostasis. The effects glucocorticoids, key physiological regulators, on WNK4 gene expression are still unknown. Here, we used dexamethasone (Dex) to treat human embryo kidney 293 (HEK293) cells found decrease ( hWNK4 ) mRNA level by northern blot real-time quantitative PCR. After transcriptional initiation site was located 5′ rapid amplification cDNA end...