A5011949935- Health Systems, Economic Evaluations, Quality of Life
- Advanced Causal Inference Techniques
- Bone health and treatments
- Statistical Methods in Clinical Trials
- Bone health and osteoporosis research
- Sex work and related issues
- Child Nutrition and Water Access
- Statistical Methods and Bayesian Inference
- Poverty, Education, and Child Welfare
- Parathyroid Disorders and Treatments
- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- Statistical Methods and Inference
- Healthcare Policy and Management
- Pharmaceutical Practices and Patient Outcomes
- Global Maternal and Child Health
- Rheumatoid Arthritis Research and Therapies
- Pharmaceutical studies and practices
- Diabetes Treatment and Management
- Bone fractures and treatments
- Health, Environment, Cognitive Aging
- Viral Infections and Immunology Research
- Statistical Methods and Applications
- Folate and B Vitamins Research
- Health disparities and outcomes
University for Development Studies
2025
London School of Hygiene & Tropical Medicine
2018-2025
Faculty of Public Health
2020-2024
Centre for Sexual Health and HIV AIDS Research
2024
Fundação Oswaldo Cruz
2019-2023
Liverpool School of Tropical Medicine
2023
Knowledge Integration (United Kingdom)
2019-2023
Royal Society of Tropical Medicine and Hygiene
2022
University of Oxford
2016-2021
Nuffield Orthopaedic Centre
2016-2021
Interrupted time series (ITS) analysis is being increasingly used in epidemiology. Despite its growing popularity, there a scarcity of guidance on power and sample size considerations within the ITS framework. Our aim this study was to assess statistical detect an intervention effect under various real-life scenarios. datasets were created using Monte Carlo simulations generate cumulative incidence (outcome) values over time. We generated 1,000 per scenario, varying number points, average...
Female sex workers remain disproportionately affected by HIV. The aim of this study was to determine the effect risk-differentiated, peer-led support for female in Zimbabwe on risk HIV acquisition and transmission from among workers.
Abstract Background Record linkage is the process of identifying and combining records about same individual from two or more different datasets. While there are many open source commercial data tools, volume complexity currently available datasets for pose a huge challenge; hence, designing an efficient tool with reasonable accuracy scalability required. Methods We developed CIDACS-RL (Centre Data Knowledge Integration Health – Linkage), novel iterative deterministic record algorithm based...
Bisphosphonates are the first-line treatment for preventing fractures in osteoporosis patients. However, their use is contraindicated or to be used with caution chronic kidney disease (CKD) patients, primarily because of a lack information about safety and effectiveness. We aimed investigate oral bisphosphonates patients moderate severe CKD, using primary-care electronic records from two cohorts, CPRD GOLD (1997-2016) SIDIAP (2007-2015) UK Catalonia, respectively. Both databases were linked...
The Center for Data and Knowledge Integration Health (CIDACS) was created in 2016 Salvador (Bahia, Brazil). This paper aims to present a profile of CIDACS, including its current databases. CIDACS conduct interdisciplinary studies research, develop new scientific methodology promote professional training using linked large-scale databases high-performance computational resources secure environment. Administrative data is at the core activities conducted by CIDACS. advantages administrative...
Bias in epidemiological studies can adversely affect the validity of study findings. Sensitivity analyses, known as quantitative bias are available to quantify potential residual arising from measurement error, confounding, and selection into study. Effective application these methods benefits input multiple parties including clinicians, epidemiologists, statisticians. This article provides an overview a few common facilitate both use critical interpretation applications published...
Abstract Background Sudan is a large country with diverse population and history of civil conflict. Poverty levels are high gross national income per capita less than two thousand dollars. The has burden tuberculosis (TB) an estimated 50,000 incident cases during 2009, when the prevalence was 209 100,000 population. Few studies have been undertaken on TB in drug resistant disease not known. Methods In this study Mycobacterium isolates from 235 patients attending three treatment centers were...
Conditional on the propensity score (PS), treated and untreated subjects have similar distribution of observed baseline characteristics when PS model is appropriately specified. The performance several balance measures in assessing covariates achieved by a specific selecting optimal was evaluated simulation studies. However, these studies involved only normally distributed covariates. Comparisons binary or mixed covariate distributions with rare outcomes, typical pharmacoepidemiologic...
Background Brazil has made great progress in reducing child mortality over the past decades, and a parcel of this achievement been credited to Bolsa Família program (BFP). We examined association between being BFP beneficiary (1–4 years age), also examining how differs by maternal race/skin color, gestational age at birth (term versus preterm), municipality income level, index quality management. Methods findings This is cross-sectional analysis nested within 100 Million Brazilian Cohort,...
Cardiovascular disease (CVD) has a disproportionate effect on mortality among the poorest people. We assessed impact CVD and all-cause of world's largest conditional cash transfer, Brazil's Bolsa Família Programme (BFP).
Abstract Background Observational studies including time‐varying treatments are prone to confounding. We compared Cox regression analysis, propensity score (PS) methods, and marginal structural models (MSMs) in a study of antidepressant [selective serotonin reuptake inhibitors (SSRIs)] use the risk hip fracture. Methods A cohort patients with first prescription for antidepressants (SSRI or tricyclic antidepressants) was extracted from Dutch Mondriaan Spanish Base de datos para la...
Abstract The recently deployed RTS,S/AS01 E malaria vaccine induces a strong antibody response to the circumsporozoite protein (CSP) on surface of Plasmodium falciparum sporozoite which is associated with protection. anti-CSP titre falls rapidly after primary vaccination, decline in efficacy, but and protective can be partially restored by booster dose vaccine, this also transitory. In many malaria- endemic areas Africa, children are at risk malaria, including severe until they five years...
WHO recommended two novel vaccines, RTS,S AS01E and R21 Matrix M, against malaria caused by Plasmodium falciparum. For both the schedule is 4 doses starting from age of 5 months, in children living regions with moderate to high transmission, an optional dose for areas highly seasonal transmission.