A5008613527- Diabetes, Cardiovascular Risks, and Lipoproteins
- Thyroid Disorders and Treatments
- Diabetes and associated disorders
- Diabetes Management and Research
- Bone health and treatments
- Pregnancy and preeclampsia studies
- Pituitary Gland Disorders and Treatments
- Diabetes Treatment and Management
- Thyroid Cancer Diagnosis and Treatment
- Bone health and osteoporosis research
- Cardiovascular Function and Risk Factors
- Diabetic Foot Ulcer Assessment and Management
- Gestational Diabetes Research and Management
- Immune Cell Function and Interaction
- Cardiovascular Health and Disease Prevention
- Vitamin D Research Studies
- Lipoproteins and Cardiovascular Health
- T-cell and B-cell Immunology
- Helicobacter pylori-related gastroenterology studies
- COVID-19 Clinical Research Studies
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Metabolism, Diabetes, and Cancer
- Peripheral Artery Disease Management
- Growth Hormone and Insulin-like Growth Factors
Hospital Universitari Germans Trias i Pujol
2014-2025
Instituto de Salud Carlos III
2002-2024
Centro de Investigación Biomédica en Red Diabetes y Enfermedades Metabólicas Asociadas
2015-2024
Universitat Autònoma de Barcelona
2013-2024
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2012-2024
Institut Universitari d'Investigació en Atenció Primària Jordi Gol
2024
Centre for Biomedical Network Research on Rare Diseases
2018
Washington University in St. Louis
2013
Banc de Sang i Teixits
2011
Aims: To compare glycemic control and maternal–fetal outcomes of women with type 1 diabetes (T1D) using hybrid closed loop (HCL) vs. multiple daily insulin injections (MDI) plus continuous glucose monitoring (CGM). Methods: Multicenter prospective cohort study pregnant T1D in Spain. We evaluated HbA1c time spent within (TIR), below (TBR) above (TAR) the pregnancy-specific range 3.5–7.8 mmol/L. Adjusted models were performed for adverse pregnancy including baseline maternal characteristics...
Despite normal to high bone mineral density, patients with type 2 diabetes (T2DM) have an increased fracture risk. T2DM medications could partially account for this excess The aim of study was assess the association between insulin use and risk in patients. A population-based matched cohort based on a primary care records database validated research (Catalonia, Spain) performed. Propensity score (PS) calculated using logistic regression including predefined predictors fractures. total 2,979...
Objective To investigate longitudinal changes in the liver stiffness measurement (LSM) general adult population without known disease and to describe its association with metabolic risk factors, a special focus on subjects non-alcoholic fatty (NAFLD) dysglycemia. Material Methods A population-based cohort study was conducted Catalonia. LSM measured by transient elastography (TE) at baseline follow-up (median: 4.2 years). Subgroup NAFLD dysglycemia were analyzed. Moderate-to-advanced fibrosis...
Patients affected by COVID-19 may develop disease related malnutrition (DRM) due to the catabolic situation, symptoms that interfere with intake and prolonged hospital stay. This study aims know percentage of patients admitted for who required artificial nutrition (AN), their clinical characteristics, as well prevalence DRM risk sarcopenia at discharge after 6 months.Observational, prospective study, successive inclusion adult in whom institutional nutritional support (NS) care protocol was...
Introduction: The diagnosis of acromegaly is often delayed, leading to facial disfigurements that persist despite endocrine cure. We aimed study the relationship between modifications, Quality Life (QoL), and psychologic status in patients with acromegaly. Methods: Sixty-five remission or hormonal disease control participated (29 women 36 men; mean age 57.4±13.5 years). following variables were assessed: a) life using AcroQoL; b) Anxiety level STAI Questionnaire; c) Self-esteem by Rosemberg...
Summary Objective An association of pregnancy outcomes with subclinical hypothyroidism has been reported; however, there still exists a strong controversy regarding whether ought to be dealt or not. The objective the study was evaluate foetal‐maternal complications first trimester maternal Thyrotropin ( TSH ) values. Design A retrospective in single tertiary care hospital performed. Patients total 1981 pregnant women were studied during 2012. Measurements universal screening performed...
Individuals with diabetes have remarkably high rates of cardiovascular morbidity and mortality. However, the incremental risk in is heterogeneous has often been related to renal involvement. The purpose this study was analyse prognostic value subclinical atherosclerosis determining incidence first events (CVEs) individuals chronic kidney disease (CKD) compared CKD without diabetes.
Lipoprotein disturbances have been associated with increased cardiovascular disease (CVD) risk in type 1 diabetes mellitus (T1DM). We assessed the advanced lipoprotein profile T1DM individuals, and analysed differences non-diabetic counterparts.This cross-sectional study involved 508 adults 347 controls, recruited from institutions a Mediterranean region of Spain. Conventional (assessed by nuclear magnetic resonance [NMR] spectroscopy) profiles were analysed. Crude adjusted (by age, sex,...
To investigate the prevalence and risks factors associated with presence of liver fibrosis in subjects nonalcoholic fatty disease (NAFLD) without type 2 diabetes mellitus (T2D).This study was part a population-based conducted Barcelona metropolitan area among aged 18-75 years old. Secondary causes steatosis were excluded. Moderate-to-advanced defined as stiffness measurement (LSM) ≥ 8.0 kPa assessed by transient elastography.Among 930 NAFLD, moderate-to-advanced higher T2D compared those...
The glycoprotein YKL-40 is a new marker of early inflammation and endothelial dysfunction. Adiponectin collagen-like protein with anti-atherogenic anti-inflammatory effects. Increased concentrations both markers have been reported in patients type 1 diabetes (T1D). To assess the possible role adiponectin as subclinical cardiovascular disease asymptomatic no history ischemic or macrovascular heart its relationship other classic inflammatory biomarkers. Concentrations YKL-40, adiponectin,...
Summary. Resolution of hepatitis C virus (HCV) infection requires a complex interplay between innate and adaptative immune responses. The role lymphocyte subpopulations during combined antiviral treatment remains to be defined. This study was conducted assess the effect pegylated interferon-alpha2a (pegIFN-α2a) ribavirin on peripheral blood lymphocytes, mainly CD81 expression B cells CD4+CD25+CD127low/−FoxP3+ regulatory T (Tregs) in patients with chronic HCV infection. Thirty-five who...
To evaluate the presence of early carotid and coronary atherosclerosis in asymptomatic patients with type 1 diabetes no history ischemic heart disease.One hundred fifty (58% males; 38.6 ± 8.1 years, 20.4 years evolution; HbA1c 2.3%; 52% nonsmokers; 26% retinopathy; 9% microalbuminuria) 50 nondiabetic control subjects age sex matched were studied. Carotid ultrasonography to determine common artery intima-media thickness (c-IMT) atheroma plaques cardiac computed tomography for calcium analysis...
Aging | doi:10.18632/aging.203615. Esmeralda Castelblanco, Maria R. Sarrias, Àngels Betriu, Berta Soldevila, Barranco-Altirriba, Josep Franch-Nadal, Jose M. Valdivielso, Marcelino Bermudez-Lopez, Per-Henrik Groop, Elvira Fernández, Núria Alonso, Didac Mauricio
Background: The basal−bolus insulin regimen is recommended in hospitalized patients with diabetes mellitus (DM), but has an increased risk of hypoglycemia. We aimed to compare dipeptidyl peptidase 4 inhibitors (DPP4-i) and glycemic outcomes type 2 DM patients. Methods patients: Our prospective randomized study included 102 elderly T2DM (82 ± 9 years, HbA1c 6.6% 1.9). Glycemic control: A variability coefficient assessed by continuous glucose monitoring (Free Style® sensor), mean dose...