A5075379454- Traditional Chinese Medicine Studies
- Spine and Intervertebral Disc Pathology
- Bone health and osteoporosis research
- Musculoskeletal pain and rehabilitation
- Bone Metabolism and Diseases
- Myofascial pain diagnosis and treatment
- Medical Imaging and Analysis
- Medical Research and Treatments
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- Healthcare and Venom Research
- Spinal Fractures and Fixation Techniques
- Medicinal Plant Pharmacodynamics Research
- Cardiovascular and exercise physiology
- High Altitude and Hypoxia
- Muscle Physiology and Disorders
- Bioinformatics and Genomic Networks
- Laser Applications in Dentistry and Medicine
- Acupuncture Treatment Research Studies
- Anatomy and Medical Technology
- 3D Printing in Biomedical Research
- Genetics and Physical Performance
- Meta-analysis and systematic reviews
- Cervical and Thoracic Myelopathy
- Infrared Thermography in Medicine
The Third Affiliated Hospital of Zhejiang Chinese Medical University
2017-2025
Zhejiang Chinese Medical University
2016-2024
Yigu decoction (YGD) is a traditional Chinese medicine prescription for the treatment of osteoporosis, although many clinical studies have confirmed its anti-OP effect, but specific mechanism still not completely clear.
Disordered gut microbiota (GM) structure and function may contribute to osteoporosis (OP). This study explores how traditional Chinese medicine (TCM) intervention affects the of GM in patients with OP. In a 3-month clinical study, 43 were randomly divided into two groups receiving conventional treatment combined TCM (Yigu decoction, YGD) treatment. The correlation between intestinal flora its metabolites was analyzed using 16S rDNA untargeted metabolomics combination two. After three months...
Pain is considered a multidimensional conscious experience that includes sensory component and negative affective-motivational component. The of pain different from the amplifies experience. Nowadays, significant number preclinical research groups have focused their attention on affective symptoms pain. In present study, we investigated aversion anxiety-like behavior complete Freund's adjuvant (CFA)-induced chronic model. CFA rats experienced spontaneous during pain-paired conditioning (pain...
The aim of the present study was to evaluate relative functional volume bilateral lumbar multifidus (LM) muscles across different stages and ages patients with disc herniation (LDH). volumes LM in both non-affected affected sides L4-L5 L5-S1 segmental level were measured a resting prone position, visual analogue score (VAS) for pain Japanese Orthopedic Association (JOA) scores recorded. correlation between changes net times onset, ages, VAS JOA analyzed. A total 327 cases selected. could...
Background: This study aims to evaluate the association between serum alkaline phosphatase (ALP), calcium (Ca) and phosphorus (P), C-reactive protein (CRP) D-dimer (D-D), hemoglobin (Hb) in postoperative preoperative osteoporotic hip fracture elderly patients. Methods: A total of 32 operation patients with over age 65 years old were admitted orthopedic unit prospectively evaluated. All treated according specific protocols, type fracture. Fasting blood samples taken, ALP, Ca P measurements...
Osteoporosis (OP) is a systemic bone disease characterized by decreased mass, destruction of the tissue microstructure, increased brittleness and an risk fracture. OP has high incidence rate long course associated with serious complications. Yigu decoction (YGD) compound prescription in traditional Chinese medicine that used to treat OP. However, its mechanism not clear. This study tandem mass tag (TMT)quantitative proteomics method explore potential bone-protective YGD osteoporotic rat...
Bibliometrics was employed in this study to determine the research trends worldwide application of 3D printing technology treat bone tumors over previous 10 years.
Abstract Doxorubicin (DOX) is an anthracycline antibiotic used in the clinical treatment of cancer, but its use limited due to cardiotoxic effects. Therefore, it necessary explore natural compounds that are effective protecting against cardiotoxicity caused by DOX. Neutral Morchella conica polysaccharides‐2 (NMCP‐2) a polysaccharide with antioxidant activity was isolated and purified from our laboratory's previous study. This study aimed investigate possible protective effect NMCP‐2 on...
Osteoporosis is a metabolic bone disease characterized by age-related loss of mass, destruction microstructure, increased brittleness and susceptibility to fracture. The often occurs in postmenopausal women middle-aged elderly men, with insidious onset, most patients were diagnosed after fracture, resulting lot consumption medical resources. Based on the basic theories such as "kidney governing bone" deficiency", professor YAO Xinmiao Third Affiliated Hospital Zhejiang Chinese Medical...
Background Postmenopausal osteoporosis (PMOP) is a serious condition that affects elderly individuals. Our previous study revealed Yigu decoction (YGD) effectively improved bone mineral density (BMD) in individuals, but the mechanism underlying this effect remains unclear. In study, we investigated relationships among YGD, microRNAs (miRNAs), and metabolism by assessing effects of YGD on miRNA levels patient plasma to provide scientific basis for treating PMOP with YGD. Methods clinical...
Introduction As populations age, osteoporosis has become a hot topic of global public concern. The beneficial effects traditional Chinese exercises on the musculoskeletal system have been demonstrated. However, previous research findings are inconsistent, and it is unclear which type exercise its frequency duration best effect osteoporosis. This study aims to investigate most appropriate modality for people with through systematic evaluation network meta-analysis guide clinical practice....
Purpose: To study the anti-osteoporotic effect of Shengu'an in rats, and elucidate mechanism action involved.Methods: Forty healthy female SPF mice were randomly divided into control group, saline-treated TGFβRⅡ receptor inhibitor shengu'an group. The expressions type Ⅱ collagen (Co1-II) platelet endothelial cell adhesion factor (CD-31) determined. transforming growth β1 (TGF-β1), p-smad2/3, matrix metalloproteinase-9 (MMP-9) osteoblast specific transcription (osterix) assayed by western...
Abstract Background Tennis elbow has long been one of the most controversial subjects in orthopaedics. Many scholars thought use open or arthroscopic surgery was reserved for patients with refractory symptoms. Therapy percutaneous acupotomy performed under local anaesthesia also removes degenerated tissue, releases strain, and therefore provides an alternative treatment option to surgical excision. Purpose The aim this single-blinded randomized control trial examine long-term clinical...