A5088560152- Insect symbiosis and bacterial influences
- Microbial Community Ecology and Physiology
- Genomics and Phylogenetic Studies
- Reproductive tract infections research
- Biofuel production and bioconversion
- Entomopathogenic Microorganisms in Pest Control
- Plant and animal studies
- Mosquito-borne diseases and control
- Plant and fungal interactions
- Protist diversity and phylogeny
- Vector-borne infectious diseases
- Insect and Arachnid Ecology and Behavior
- Plant Virus Research Studies
- Insect behavior and control techniques
- Insect and Pesticide Research
- Mycorrhizal Fungi and Plant Interactions
- Trypanosoma species research and implications
- Phytoplasmas and Hemiptera pathogens
- Plant Pathogens and Fungal Diseases
- Evolution and Genetic Dynamics
- Fungal Biology and Applications
- Insect-Plant Interactions and Control
- Genetics, Bioinformatics, and Biomedical Research
- Research on Leishmaniasis Studies
University of Liverpool
2020-2024
Abstract The Eukaryotic Pathogen, Vector and Host Informatics Resource (VEuPathDB, https://veupathdb.org) is a Bioinformatics Center funded by the National Institutes of Health with additional funding from Wellcome Trust. VEuPathDB supports >600 organisms that comprise invertebrate vectors, eukaryotic pathogens (protists fungi) relevant free-living or non-pathogenic species hosts. Since 2004, has analyzed omics data public domain using contemporary bioinformatic workflows, including...
Abstract FungiDB (https://fungidb.org) serves as a valuable online resource that seamlessly integrates genomic and related large-scale data for wide range of fungal oomycete species. As an integral part the VEuPathDB Bioinformatics Resource Center (https://veupathdb.org), continually both published unpublished addressing various aspects biology. Established in early 2011, database has evolved to support 674 datasets. The datasets include over 300 genomes spanning taxa (e.g. Ascomycota,...
Members of the bacterial genus Rickettsia were originally identified as causative agents vector-borne diseases in mammals. However, many species are arthropod symbionts and close relatives 'Candidatus Megaira', which symbiotic associates microeukaryotes. Here, we clarify evolutionary relationships between these organisms by assembling 26 genomes from understudied groups, including Torix group, two 'Ca. Megaira' various insects Our analyses new genomes, comparison with previously described...
Rickettsia are intracellular bacteria best known as the causative agents of human and animal diseases. Although these medically important often transmitted via haematophagous arthropods, other Rickettsia, such those in Torix group, appear to reside exclusively invertebrates protists with no secondary vertebrate host. Importantly, little is about diversity or host range group Rickettsia.
Symbiotic microbes from the genus 'Candidatus Megaira' ( Rickettsiales ) are known to be common associates of algae and ciliates. However, genomic resources for these bacteria scarce, limiting our understanding their diversity biology. We therefore utilize Sequence Read Archive metagenomic assemblies explore this genus. successfully extract four draft ' Ca . genomes including one complete scaffold a Megaira identify an additional 14 uncategorized environmental metagenome-assembled genomes....
Abstract Phlebotomine sand flies are the vectors of leishmaniasis, a neglected tropical disease. High-quality reference genomes an important tool for understanding biology and eco-evolutionary dynamics underpinning disease epidemiology. Previous leishmaniasis vector sequences were limited by sequencing technologies available at time inadequate high-resolution genomic inquiry. Here, we present updated assemblies two flies, Phlebotomus papatasi Lutzomyia longipalpis . These chromosome-level...
Abstract Heritable microbes are an important component of invertebrate biology, acting both as beneficial symbionts and reproductive parasites. Whilst most previous research has focussed on the ‘ Wolbachia pandemic’, recent work emphasised importance other microbial symbionts. In this study, we present a survey odonates (dragonflies damselflies) for torix group Rickettsia , following indicating that clade can be common in aquatic insect groups. PCR assays were used to screen broad range from...
Chlamydiota are an ancient and hyperdiverse phylum of obligate intracellular bacteria. The best characterized representatives pathogens or parasites mammals, but it is thought that their most common hosts microeukaryotes like Amoebozoa. diversity in taxonomy, evolution, function non-pathogenic slowly being described. Here we use data mining techniques genomic analysis to extend our current knowledge its hosts, particular the Order Parachlamydiales. We extract one Rhabdochlamydiaceae three...
Rickettsia are intracellular bacteria best known as the causative agents of human and animal diseases. Although these medically important often transmitted via haematophagous arthropods, other Rickettsia, such those in Torix group, appear to reside exclusively invertebrates protists with no secondary vertebrate host. Importantly, little is about diversity or host range group Rickettsia. This study describes serendipitous discovery amplicons Barcode Life Data System (BOLD), a sequence...
Abstract Symbiotic bacteria can alter host biology by providing protection from natural enemies, or reproduction vectoral competence. Symbiont‐linked control of vector‐borne disease in Anopheles has been hampered a lack symbioses that establish stable vertical transmission the host. Previous screening found symbiont ‘ Candidatus Tisiphia’ plumbeus , an aggressive biter and potential secondary vector malaria parasites West Nile virus. We screened samples collected over 10‐years across Germany...
Abstract Rickettsia are intracellular bacteria originally described as arthropod borne pathogens that emerging a diverse group of often biologically important, non-pathogenic symbionts invertebrates and microeukaryotes. However, sparse genomic resources for symbiotic strains the sister genus ( Candidatus Megaira) inhibit our understanding evolution biology. Here, we present first closed genomes Ca . Megaira from an alga Mesostigma viride ), Torix midge Culicoides impunctatus ) bed bug Cimex...
Abstract Symbiotic bacteria alter host biology in numerous ways, including the ability to reproduce or vector disease. Deployment of symbiont control borne disease has focused on Wolbachia interactions with Aedes and is hampered Anopheles by a lack compatible symbioses. Previous screening found ‘ Ca . Tisiphia’ plumbeus , an aggressive biter potential secondary malaria parasites West Nile virus. We screen An. samples collected over ten-year period across Germany use climate databases assess...
Abstract Chlamydiota are an ancient and hyperdiverse Phylum of obligate intracellular bacteria. The best characterized representatives pathogens or parasites mammals, but it is thought that their most common hosts microeukaryotes like Amoebozoa. diversity in taxonomy, evolution, function non-pathogenic slowly being described. Here we use data mining techniques genomic analysis to extend our current knowledge its hosts, particular the Order Parachlamydiales . We extract one...
Abstract Symbiotic microbes from the genus ‘ Candidatus Megaira’ (Rickettsiales) are known to be common associates of algae and ciliates. However genomic resources for these bacteria scarce, limiting our understanding their diversity biology. We therefore utilized SRA metagenomic assemblies explore this genus. successfully extracted four draft Ca . genomes including one complete scaffold a identified an additional 14 uncategorised environmental Metagenome-Assembled Genomes. use information...