A5056917577- Arsenic contamination and mitigation
- Heavy Metal Exposure and Toxicity
- Oral microbiology and periodontitis research
- Dental Health and Care Utilization
- Selenium in Biological Systems
- Salivary Gland Disorders and Functions
- Fluoride Effects and Removal
- Innovations in Medical Education
- Empathy and Medical Education
- Folate and B Vitamins Research
- Glutathione Transferases and Polymorphisms
- Connexins and lens biology
- Bladder and Urothelial Cancer Treatments
- Dental Radiography and Imaging
- Immune Response and Inflammation
- Air Quality and Health Impacts
- Heavy metals in environment
- S100 Proteins and Annexins
- Genomics, phytochemicals, and oxidative stress
- Thermoregulation and physiological responses
- Epigenetics and DNA Methylation
- Dental Research and COVID-19
- Heme Oxygenase-1 and Carbon Monoxide
- Fungal Biology and Applications
- HIV/AIDS oral health manifestations
Kaohsiung Medical University
2019-2025
Kaohsiung Medical University Chung-Ho Memorial Hospital
2022-2023
Taipei Medical University
2010-2019
Cathay General Hospital
2013
Institute of Medical Sciences
2009
Tzu Chi University
2006-2008
Buddhist Tzu Chi General Hospital
2008
University of Saskatchewan
2006
Using DNA methylation biomarkers in cancer detection is a potential direction clinical testing. Some methylated genes have been proposed for cervical detection; however, more reliable markers are needed. To identify new hypermethylated the discovery phase, we compared methylome between pool of from normal epithelium (n = 19) and tissues 38) using bead array. We integrated differentially with public gene expression databases, which resulted 91 candidate genes. Based on after demethylation...
Abstract Periodontitis ( PD ) is an inflammatory disease characterized by gingival inflammation and resorption of alveolar bone. Impaired receptor activator nuclear factor‐kappa B ligand/osteoprotegerin RANKL / OPG signaling caused enhanced production pro‐inflammatory cytokines plays essential role in the pathogenesis . Considering melatonin possesses significant anti‐inflammatory property, this study aimed to determine whether prophylactic treatment with would effectively normalize...
The 17 sustainable development goals (SDGs) were established by the United Nations Agenda 2030 plan of action to achieve peace, prosperity, and well-being for all 2030. SDG 3 aims ensure healthy lives promote at ages. However, oral health is not specifically mentioned targeted in 3. Numerous studies have demonstrated a connection between general health. Oral disease common non-communicable diseases co-existing modifying risk factors. In addition, associated with social, economic, cultural,...
Purposes: To explore the associated factors of COVID-19 vaccine hesitancy and examine psychometric properties coronavirus-related health literacy questionnaire (HLS-COVID-Q22) Oxford Vaccine Hesitancy questionnaire. Methods: An online survey was conducted from 23 June to 16 July 2021 on 387 school principals across Taiwan. Data collection included socio-demographic characteristics, information related work, physical mental health, perceptions, sense coherence, literacy, hesitancy. Principal...
Salivary levels of interleukin-8 (IL-8) are elevated in patients with periodontitis. Caffeic acid phenethyl ester (CAPE) improves the periodontal status subjects. However, whether CAPE can reduce IL-8 expression is unclear. We collected saliva to determine proinflammatory cytokine and used subgingival calculus surrounding tissues from periodontitis for oral microbiota analysis via 16s ribosomal RNA gene sequencing. THP-1 cells were stimulated sterile-filtered patients, target gene/protein...
Vascular inflammatory process has been suggested to play a key role in the initiation and progression of atherosclerosis, major complication diabetes mellitus. Recent studies have shown that brazilin exhibits antihepatotoxic, antiplatelet, cancer preventive, or anti-inflammatory properties. Thus, we investigated whether suppresses vascular induced by high glucose (HG) cultured human umbilical vein endothelial cells (HUVEC). HG nitrite production, lipid peroxidation, intracellular reactive...
Abstract The aim of this study was to evaluate the associations between cigarette use and five salivary oxidative stress biomarkers, copper-zinc superoxide dismutase (Cu/Zn SOD), manganese (MnSOD), catalase, thioredoxin-1 (TRX1), peroxiredoxin-2 (PRX2), assess effectiveness non-surgical periodontal therapy. Materials Methods: This is an observational study,167 patients diagnosed with periodontitis were recruited. Both saliva samples clinical measurements (plaque index (PI), bleeding on...
Background: Matrix metalloproteinases (MMPs) play important roles in the invasion and migration of cancer cells. In melanoma, several signaling pathways are constitutively activated. Among these, mitogen-activated protein kinase (MAPKs) activated through multiple signal transduction molecules appear to major melanoma progression. Therefore, inhibition MAPK might be a crucial role for treatment cancer. Aims: We examined anticancer effect CME-1, novel water-soluble polysaccharide fraction,...