In the application of microarray data, how to select a small number informative genes from thousands that may contribute occurrence cancers is an important issue. Many researchers use various computational intelligence methods analyzed gene expression data. To achieve efficient selection candidate can in identifying cancers, this study aims at developing novel method utilizing particle swarm optimization combined with decision tree as classifier. This also compares performance our proposed...

An electrical field may affect osteogenesis. Since we found that hydroxyapatite (HA) ceramics be polarizable, hypothesized electrically polarized HA foster production of new bone in vivo. Both and non-polarized were inserted into the subperiosteum spaces at parietal area rats. After 2, 4, 8 weeks, implant sites examined histologically. Morphometric analysis revealed formation was accelerated on negatively charged surface (N-surface) 2 weeks. The newly formed approached maturation 4 weeks...

The biocharacteristics of xenogeneic grafts make them a possible substitute for autogenous bone in dental graft procedures. This study aimed to develop novel porcine with collagen capable generating new defects via osteoconduction over 8 weeks healing and compare it graft. was made undergo cell viability test (MTT) alkaline phosphatase assay (ALP). surgical procedure performed 20 male adult New Zealand white rabbits. Four calvarial critical-size 6 mm diameter were prepared each rabbit. upper...

A major number of studies have demonstrated Beta-tricalcium phosphate (β-TCP) biocompatibility, bioactivity, and osteoconductivity characteristics in bone regeneration. The aim this research was to enhance β-TCP's evaluate its physicochemical properties by argon glow discharge plasma (GDP) surface treatment without modifying surface. Treated β-TCP analyzed scanning electron microscopy (SEM), energy-dispersive spectrometry, X-ray photoelectron spectroscopy (XPS), diffraction analysis, Fourier...

Abstract The aim of this study was to evaluate the associations between cigarette use and five salivary oxidative stress biomarkers, copper-zinc superoxide dismutase (Cu/Zn SOD), manganese (MnSOD), catalase, thioredoxin-1 (TRX1), peroxiredoxin-2 (PRX2), assess effectiveness non-surgical periodontal therapy. Materials Methods: This is an observational study,167 patients diagnosed with periodontitis were recruited. Both saliva samples clinical measurements (plaque index (PI), bleeding on...

Introduction: To overcome the genuine bioinert properties of zirconia ceramic, functionalization surface with bioactive protein fibronectin was conducted. Methods: Glow discharge plasma (GDP)-Argon first used to clean surface. Then allylamine treated at three different powers 50 W, 75 and 85 W immersed into 2 concentrations (5 µg/ml 10 µg/ml). Results Discussion: After treatment, irregularly folded protein-like substances were attached on coated disks, a granular pattern observed for grafted...

Antimicrobials are important adjuncts in the treatment of caries and periodontitis. However, increased bacterial resistance hypersensitivity reactions to commonly used antimicrobials have led an increasing demand for safe natural substances. The objective this study was investigate antibacterial effects ε-polylysine against oral pathogens

The objective of this study was to evaluate the antibacterial efficacy against Enterococcus faecalis and Streptococcus mutans in vivo toxicity using embryonic zebrafish assays sodium hypochlorite (NaOCl) electrolyzed oxidizing (EO) water (containing hypochlorous acid (HOCl))-based root canal irrigating solutions. Methodology: Using 100 μL microbial count 1 × 108 cfu/mL mix with each 10 mL specimen NaOCl or HOCl for designed time periods. above protocol also repeated mutans. concentration...

Guided-bone regeneration (GBR) is increasingly using three-dimensional (3D) printing by fused deposition modeling (FDM) to build the filaments used for treatment. Polylactic acid (PLA) and beta-tricalcium phosphate (β-TCP) are widely as base materials in 3D printing, necessitating that they studied together context of GBR This study sought test compare properties efficacy different ratios β-TCP PLA make 3D-printed filament material find most effective combination Several were tested,...

In vitro, in vivo, and clinical studies have shown how the physicochemical biological properties of β-tricalcium phosphate (β-TCP) work bone regeneration. This study aimed to improve β-TCP by achieving optimum surface bulk chemical/physical through hydrothermal addition magnesium (Mg) later establish biocompatibility β-TCP/Mg for grafting tissue engineering treatments. Multiple vitro vivo analyses were used complete characterization. The MgO brought about a modest rise number particles,...

Modification of the physiochemical properties titanium surfaces using glow discharge plasma (GDP) and fibronectin coating has been shown to enhance surface hydrophilicity, roughness, cell adhesion, migration, proliferation. This in vivo study aimed evaluate bone integration efficacy a biologically modified implant surface. Two different surface-modified implants (Ar-GDP GDP-fib) were placed mandibular premolar area six beagle dogs for 2-8 weeks. Three techniques [histologic evaluation,...

The benefits and feasibility of platform switching have been discussed in several studies, reporting lesser crestal bone loss platform-switched implants than platform-matched implants. Objective. aim the present study was to observe changes vertical horizontal marginal levels dental Materials Methods. 51 patients received 60 over a 1-year period. Measurement performed between implant shoulder most apical defect by periapical radiographs examine peri-implant alveolar before 12 months after...

For years, in order to improve bone regeneration and prevent the need of a second stage surgery remove non-resorbable membranes, biological absorbable membranes have gradually been developed applied guided tissue (GTR). The present study’s main objective was achieve space maintenance using new freeze-dried porcine collagen membrane, compare it with an already commercial when both were used bovine xenograft prepared alveolar ridge defects. Prior surgery, membrane’s vitality analysis showed...

Due to autogenous bone limitations, some substitute grafts were developed. Collagenated porcine graft (CPG) is able regenerate new bone, although the number of studies insufficient, highlighting need for future better understand biomaterial. In order CPG′s possible dental guided regeneration indications, aim this work was determine biological capacity induce osteoblast differentiation in vitro and vivo, whilst being compared with commercial hydroxyapatite beta tricalcium phosphate (HA/β-TCP)...

Abstract Background Glow discharge plasma ( GDP ) technology has been used to graft various proteins the titanium surface, including albumin, type I collagen, but without fibronectin. Purpose The aim of this study was evaluate and analyze physical properties fibronectin‐grafted surfaces after treatment. Materials Methods Grade II discs cleaning autoclaving were considered as original specimens, thus divided into four groups. groups different upon two treatments only fibronectin grafting...

The effect of comorbidity on lung cancer patients' survival has been widely reported. aim this study was to investigate the effects establishment diagnosis and in patients Taiwan by using a nationwide population-based design. This collected various analyzed data regarding during 16-year follow-up period (1995-2010). In total, 101,776 were included, comprising 44,770 with 57,006 without comorbidity. Kaplan-Meier analyses used compare overall between our cohort, chronic bronchitis who...

Glow discharge plasma (GDP) procedure is an effective method for grafting various proteins, including albumin, type I collagen, and fibronectin, onto a titanium surface. However, the behavior impact of (Ti) surface modification yet to be unraveled.The purpose this study evaluate analyze biological properties fibronectin-grafted Ti surfaces treated by GDP.Grade II discs were initially cleaned autoclaved obtain original specimens. Subsequently, specimens GDP grafted with fibronectin form...

Past studies in humans have demonstrated horizontal and vertical bone loss after six months following tooth extraction. Many biomaterials been developed to preserve volume Type I collagen serves as an excellent delivery system for growth factors promotes angiogenesis. Calcium phosphate ceramics also investigated because their mineral chemistry resembles human bone. The aim of this study was compare the performance a novel bioresorbable purified fibrillar hydroxyapatite/β-tricalcium...

The guided tissue regeneration (GTR) membrane is a barrier intended to maintain space for alveolar bone and periodontal ligament but prevent the migration of fast-growing soft into defect sites. This study evaluated physical properties, in vivo animal study, clinical efficacy hydrophilic PLA95/β-TCP GTR membranes prepared by electrospinning (ES). morphology cytotoxicity ES were SEM 3-(4,5-cimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) respectively. cementum height measured an...

Dental caries and periodontal disease remain the most prevalent oral health problems in world. Chewing xylitol gum may help reduce risk of periodontitis for dental benefits. However, little evidence has shown healthy food estimation by sequencing 16S rDNA microbial communities. This study investigated clinical effect chewing on plaque accumulation microbiota composition using PacBio full-length platform 24 young adults (N = 24). The participants were randomly assigned to control (no gum)...