A5027314497- Psoriasis: Treatment and Pathogenesis
- Nail Diseases and Treatments
- Autoimmune Bullous Skin Diseases
- Dermatologic Treatments and Research
- melanin and skin pigmentation
- Cutaneous lymphoproliferative disorders research
- Fungal Infections and Studies
- Dermatology and Skin Diseases
- Vascular Malformations and Hemangiomas
- Genetic and rare skin diseases.
- Skin Protection and Aging
- Acne and Rosacea Treatments and Effects
- Infectious Diseases and Mycology
- Dermatological diseases and infestations
- Plant Pathogens and Fungal Diseases
- Contact Dermatitis and Allergies
- Skin Diseases and Diabetes
- Insects and Parasite Interactions
- Soft tissue tumors and treatment
- Health Systems, Economic Evaluations, Quality of Life
- Histiocytic Disorders and Treatments
- Infectious Diseases and Tuberculosis
- Mosquito-borne diseases and control
- Allergic Rhinitis and Sensitization
- Systemic Lupus Erythematosus Research
Universidade do Estado do Rio de Janeiro
2015-2025
Hospital Universitário Pedro Ernesto
2003-2025
Hospital of the University of Pennsylvania
2025
Pontifical Catholic University of Rio de Janeiro
2024
Universidade Federal do Rio de Janeiro
2016-2020
Institute of Dermatology
2006-2016
Santa Casa de Misericórdia de Passos
2012-2014
University Gama Filho
2005-2013
Brazilian Medical Association
2013
Centro Brasileiro de Estudos em Dermatologia
2004
Of all the therapeutic options available in Dermatology, few of them have history, effectiveness, and safety phototherapy. Heliotherapy, NB-UVB, PUVA, UVA1 are currently most common types phototherapy used. Although psoriasis is frequent indication, it used for atopic dermatitis, vitiligo, cutaneous T-cell lymphoma, sclerosis, among others. Before indicating phototherapy, a complete patient assessment should be performed. Possible contraindications actively searched essential to assess...
Abstract Hydroquinone is the first choice of topical bleaching agents used in treatment melasma. In Brazil, hydroquinone widely prescribed by physicians and often patients without a prescription. The principal adverse effects its chronic use are confetti‐like depigmentation exogenous ochronosis. latter manifests clinically with gray‐brown or blue‐black hyperpigmentation, as well pinpoint hyperchromic papules that look like caviar, therefore called caviar‐like. On histopathology, curved...
Melasma is an acquired, irregularly patterned, light to dark-brown hypermelanosis, with symmetric distribution mostly over the face. The aim of this study was evaluate clinical characteristics and factors related melasma in Brazilian patients.This a cross-sectional, multicenter performed Brazil. Investigators examined questioned 953 patients 18 years age on other their melasma.Melasma more prevalent women (97.5%) Fitzpatrick skin phototypes II (12.8%), III (36.3%), IV (39.7%). Skin family...
Abstract Background The relapsing nature of melasma emphasizes the need to maintain efficacy achieved after acute treatment. Objective To compare clinical and safety two 6‐month Triple Combination (TC; containing fluocinolone acetonide, hydroquinone tretinoin) maintenance regimens in subjects with moderate severe melasma, daily treatment up 8 weeks. Methods This randomized, investigator‐blinded, controlled study had a phase 6 months. Sixteen centres Brazil Mexico enrolled 242 18 years or...
Psoriasis is a chronic inflammatory disease that affects 1.3% of the Brazilian population. The most common clinical manifestations are erythematous, scaling lesions affect both genders and can occur on any anatomical site, preferentially involving knees, elbows, scalp genitals. Besides impact quality life, systemic nature makes psoriasis an independent risk factor for cardiovascular disease, especially in young patients with severe disease. By initiative Society Dermatology, dermatologists...
Trichotillomania and patchy alopecia areata have similar clinical dermoscopic features.In trichotillomania, dermoscopy shows decreased hair density, short vellus hair, broken hairs with different shaft lengths, coiled hairs, trichoptilosis, sparse yellow dots, which may or not contain black dots no exclamation mark hairs.In the case of absence suggests a diagnosis trichotillomania. On other hand, finding without does exclude it.
Interest has increased in comorbidities associated with psoriasis and their effects on health-related quality of life (HRQoL). This study aimed to evaluate the prevalence metabolic syndrome (MetS) psoriatic arthritis (PsA) investigate HRQoL hypertension, type 2 diabetes mellitus (T2DM), obesity dyslipidemia. In a cross-sectional design, patients diagnosed plaque answered an interview standardized questionnaires (Dermatology Life Quality Index questionnaire [DLQI], 36-Item Short Form Health...
Psoriasis is an immune-mediated, chronic, inflammatory disease, which has a substantial humanistic and economic burden. This study aimed to assess the impact of this disease on health-related quality life (HRQoL), work productivity, direct indirect costs from societal perspective among Brazilian patients. cross-sectional, observational, multicenter study, enrolling patients with moderate severe plaque psoriasis according physician evaluation. Data collection was performed December 2015...
We describe a 56-year-old Brazilian woman presenting three nodular lesions on the scalp. Dermoscopy of all showed creamy-white body with central bird's feet-like structures surrounded by thorn crown, corresponding to posterior segment Dermatobia hominis larvae. These novel dermoscopic features allowed us easily diagnose furuncular myiasis.
Abstract: Five patients living in Rio de Janeiro, Brazil, were found to have Lyme disease. These are among the first known cases South America.
Os autores apresentam cinco casos de esporotricose em gestantes numa epidemia zoonótica no Rio Janeiro. São discutidos principalmente os aspectos clínicos e as dificuldades na escolha terapêutica desse grupo específico pacientes.
Confluent and reticulated papillomatosis of Gougerot Carteaud is a dermatosis that despite showing characteristic clinical signs often poorly recognized diagnosed. The authors present case with extensive skin involvement, discuss its association obesity describe dermoscopic findings making the histopathological correlation.
Abstract Background Psoriasis is a chronic inflammatory disease. Pustular, erythrodermic, and extensive plaque psoriasis are responsible for systemic complications. Systemic capillary leak syndrome the complication with greater progression to death occurs due vascular changes. Purpose The aim of this study was evaluate changes through expression CD 34 ICAM ‐1 in plaque, pustular, erythrodermic psoriasis. Methods sample consisted seven patients psoriasis, 24 moderate‐severe 14 mild 13...
Abstract Background Vitiligo is an acquired pigmentary disorder that affects approximately 0.5–2% of the world's population, and 25% cases begin before 10 years age. Although prevalent, there are few studies on characterization childhood vitiligo. Objective To evaluate clinical epidemiological characteristics Methods Transverse study conducted by reviewing data records patients under age 18 in which disease onset occurred 13 Results Predominance females (62%). The most common subtype was...
This publication is an update of the "Consensus on therapeutic management atopic dermatitis - Brazilian Society Dermatology" published in 2019, considering novel, targeted-oriented systemic therapies for dermatitis. The initial recommendations current consensus treatment patients with were based a recent review scientific data and was reached after voting. Dermatology invited 31 experts from all regions Brazil 2 international who fully contributed to process. methods included e-Delphi study...
Dowling-Degos disease (DDD) is a rare genetic of the skin (reticulate pigmented anomaly), clinically characterized by flexural brown reticulate macules, comedo-like papules on back, neck and pitted perioral or facial scars. We present case 51 year-old man with macrocomedo-like lesions, scars, cysts, hyperpigmented macules in his chest, axillae, neck, groin face. The patient reported having two children, three brothers father similar condition. histopathology biopsies was very characteristic...
Polymorphisms of the filaggrin 2 gene (rs 12568784 and rs 16899374) are associated with persistent atopic dermatitis in African American patients. Filaggrin is a protein function similar to also encoded epidermal differentiation complex on chromosome 1q21. To evaluate polymorphisms children adults verify association these severity clinical picture, presence other allergic diseases, socio-demographic factors. The study was carried out patients control group. Questionnaires were used...
A 57-year-old woman presented with periorbital ecchymoses, laxity in skin folds, polyneuropathy and bilateral carpal tunnel syndrome. biopsy of the axillary lesion demonstrated fragmentation elastic fibers, but a negative von Kossa stain, consistent cutis laxa. The diagnosis primary systemic amyloidosis was made by presence amyloid material eyelid using histopathological techniques, besides this, patient also diagnosed purpura, polyneuropathy, syndrome monoclonal gammopathy. She as suffering...
Bed bugs are hematophagous insects which due to their morphological and biological characteristics able easily adapt themselves human households. The authors describe two cases of dermatitis caused by bed bug bites in the city Rio de Janeiro, Brazil. Patients presented linear lesions usual "breakfast, lunch dinner" arrangement, suggesting this diagnosis. A visit dwellings showed infestation identified as Cimex hemipterus. knowledge these dermatological community will contribute an accurate...
Sporotrichosis is a subcutaneous fungal infection caused by Sporothrix schenckii and acquired direct inoculation. Although the majority of cases consist classic lymphocutaneous presentation, frequency atypical severe clinical forms disease has increased progressively. Systemic disseminated cutaneous sporotrichosis constitute rare variants such are generally associated with cellular immunodeficiency or debilitated states. The present paper describes first published case molluscum-like lesions...
Pemphigus vulgaris is an autoimmune disease characterized by suprabasal blisters with acantholysis, which has a fatal course in large number of untreated patients. Systemic corticosteroid therapy considered first-line therapy. Adjuvant treatment the goal sparing corticosteroids include, among others, dapsone. This drug not without side effects and its use requires clinical laboratory control. We present patient PV initially managed suboptimal dose prednisone, evolving into drug-induced...