A5063762550- Neurosurgical Procedures and Complications
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebral Venous Sinus Thrombosis
- Blood Coagulation and Thrombosis Mechanisms
- Peripheral Artery Disease Management
- Head and Neck Surgical Oncology
- Congenital Heart Disease Studies
- Spinal Hematomas and Complications
- Congenital heart defects research
- Central Venous Catheters and Hemodialysis
- Cardiovascular Conditions and Treatments
- Retinal and Optic Conditions
- Trigeminal Neuralgia and Treatments
- Renal and Vascular Pathologies
- Venous Thromboembolism Diagnosis and Management
University of Pittsburgh Medical Center
2020-2025
Neurological Surgery
2020-2025
University of Pittsburgh
2022-2025
UPMC Health System
2025
Beaumont Hospital, Royal Oak
1991
Abstract Introduction United States stroke systems are increasingly transitioning from alteplase (TPA) to tenecteplase (TNK). Real-world data on the safety and effectiveness of replacing TPA with TNK before large vessel occlusion (LVO) endovascular treatment (EVT) lacking. Methods Four Pennsylvania transitioned during study period 01/2020–06/2023. LVO patients who received intravenous thrombolysis or EVT were reviewed. Multivariate logistic analysis was conducted adjusting for age, sex,...
BACKGROUND AND OBJECTIVES: Multiple preferences exist for embolic materials selection in middle meningeal artery embolization (MMAE) chronic subdural hematoma with limited comparative literature data. Herein, we compare different materials. METHODS: Consecutive patients undergoing MMAE at 14 North-American centers (2018-2023) were classified into 3 groups: (a) particles, (b) Onyx, (c) n-butyl cyanoacrylate (n-BCA). The end points unplanned rescue surgery, radiographic success (≥50% reduction...
INTRODUCTION: Multiple preferences exist in terms of embolic materials middle meningeal artery embolization (MMAE) for chronic subdural hematoma (cSDH) with limited comparative literature data. METHODS: Consecutive patients undergoing MMAE cSDH at 14 North-American centers (2018-2023) were included. Patients classified into 3 groups a) particles, b) Onyx, c) n-BCA. The endpoints unplanned rescue surgery and radiographic success (=50% reduction thickness last imaging "minimum 2-weeks")....
BACKGROUND AND OBJECTIVES: Timing of restarting antiplatelet agents after middle meningeal artery embolization (MMAE) for chronic subdural hematoma (cSDH) is a topic controversy. The aim this study was to determine whether the timing restart MMAE cSDH affects long-term radiographic and clinical outcomes. METHODS: A multi-institutional, retrospective cohort performed using data from 4 academic medical centers that 2018 2023. Patients were prescribed an agent before included. Variables...
Background Middle meningeal artery embolization (MMAE) is a promising treatment for chronic subdural hematoma (cSDH). Cancer patients are at risk cSDH due to thrombocytopenia. The efficacy of MMAE in this population has not been studied. Methods We conducted retrospective analysis 76 who underwent 94 MMAEs 12 tertiary centers across North America and Europe between February 2018 January 2023. analyzed patient demographics, clinical profiles, procedural details, outcomes. primary outcome was...
Ruptured blister, dissecting, and iatrogenic pseudoaneurysms are rare pathologies that pose significant challenges from a treatment standpoint. Endovascular via flow diversion represents an increasingly popular option; however, drawbacks include the requirement for dual antiplatelet therapy potential thromboembolic complications, particularly acute complications in ruptured setting. The Pipeline Flex embolization device with Shield Technology (PED-Shield) offers reduced material...
BACKGROUND AND OBJECTIVES: The benefit of middle meningeal artery embolization (MMAE) in the treatment chronic subdural hematoma (CSDH) has been recently demonstrated a series clinical trials. Whether MMAE benefits “trial-ineligible” patients remains elusive. We thus sought to explore potential neurologically stable (modified Rankin Scale ≤3) with CSDHs because large size: Thickness >15 mm and/or midline shift ≥5 mm. METHODS: A prospectively maintained database was reviewed identify...
Abstract BACKGROUND While multiple new larger-bore aspiration catheters have been introduced for stroke thrombectomy, sizeable cohort outcome studies are lacking along with meaningful comparative to evaluate whether they represent a clinically relevant improvement compared predecessors. OBJECTIVE To angiographic and clinical outcomes between an 071 068 catheter. METHODS The authors reviewed institutional thrombectomy database extracting the first 150 consecutive cases utilizing React 71...
Background We report the largest multicenter experience to date of utilizing Comaneci device for endovascular treatment refractory intracranial vasospasm. Methods Consecutive patients undergoing mechanical dilatation vasospasm were extracted from prospectively maintained registries in 11 North American centers (2020–2022). Intra-arterial vasodilators (IAV) allowed, with utilized after absence vessel dilation post-infusion. Pre- and post-vasospasm scores recorded each segment, primary...
OBJECTIVE Acute basilar artery occlusion (BAO) harbors a more guarded prognosis after thrombectomy compared with anterior circulation large-vessel occlusion. Whether this is function of greater proportion atherosclerotic/intrinsic lesions not well studied. The authors aimed to elucidate the prevalence and predictors intracranial intrinsic atherosclerotic disease in patients acute BAO compare angiographic clinical outcomes between secondary embolic versus disease. METHODS A prospectively...
Persistent truncus arteriosus (TA) is an uncommon congenital cardiovascular malformation, which comprises between 0.4% and 4% of all heart defects. Occurrence TA in siblings has been reported infrequently. Twins concordant for isolated appear to have only once previously. In this paper, we describe dizygotic twin females who were TA.
Middle meningeal artery embolization (MMAE) has revolutionized the armamentarium for chronic subdural hematoma (CSDH) treatment. Technical and angiographic benchmarks to guide procedural clinical success are less well established.