Francis Ayimbila

ORCID: 0000-0002-4755-9093
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About
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Research Areas
  • Polysaccharides and Plant Cell Walls
  • Fungal Biology and Applications
  • Probiotics and Fermented Foods
  • Food composition and properties
  • Gut microbiota and health
  • Phytochemistry and Bioactivity Studies
  • Biofuel production and bioconversion
  • Cassava research and cyanide
  • Drug Transport and Resistance Mechanisms
  • GABA and Rice Research
  • Protein Interaction Studies and Fluorescence Analysis
  • Microbial Metabolites in Food Biotechnology
  • Proteins in Food Systems
  • Phytochemicals and Antioxidant Activities
  • Insect Utilization and Effects
  • Bee Products Chemical Analysis
  • Microbial Metabolism and Applications
  • Pharmacogenetics and Drug Metabolism
  • Pesticide Exposure and Toxicity
  • Enzyme Production and Characterization
  • Medicinal Plants and Bioactive Compounds
  • Protein Hydrolysis and Bioactive Peptides
  • Analytical Chemistry and Chromatography
  • Seaweed-derived Bioactive Compounds
  • Paraquat toxicity studies and treatments

Kasetsart University
2018-2025

Mahidol University
2024-2025

University for Development Studies
2021

Abstract Humans have long-used mushrooms as food and medicine, but digestion colonic fermentation of most mushrooms, including Lentinus squarrosulus is markedly unknown. Here, nutritional profile, L. powder (LP) were determined. The contained mainly carbohydrate protein. SEM F-TIR analysis the resistant hydrolysate (RH) revealed that structure ratio protein components altered, released known immunomodulation agents; beta-glucans mannose. Both LP RH promoted selected probiotic bacteria,...

10.1038/s41598-022-06648-z article EN cc-by Scientific Reports 2022-02-16

A set of 1,4-naphthoquinone (1,4-NQ) derivatives possesses various pharmaceutical activities. Among them, a synthetic 2-(4-methoxyanilino)naphthalene-1,4-dione (MN) is found to be non-cytotoxic the normal MRC-5 cells and prevent neuronal SH-SY5Y cell damage. To explore underlying interaction mechanism MN in circulatory system, silico multi-spectroscopic techniques were employed investigate complex human serum albumin (HSA) MN. The between HSA exhibited static fluorescence with potential...

10.1038/s41598-025-02787-1 article EN cc-by-nc-nd Scientific Reports 2025-06-02

4-Bromo-N-(thiazol-2-yl)benzenesulfonamide (1) is enriched with bioactive components and highlighted for its pharmacological properties. However, pharmacokinetic characteristics are yet to be reported. The interaction of compound 1 carrier proteins in the bloodstream an important factor that affects potential therapeutic efficacy. This study aimed elucidate mechanisms relation human serum albumin (HSA) using multi-spectroscopic computational techniques. Its predicted drug-like properties...

10.1016/j.ejps.2024.106961 article EN cc-by European Journal of Pharmaceutical Sciences 2024-11-09

Resistant starch (RS) enhances gastrointestinal (GI) health but RS content in rice varies depending on cooking and storage conditions. Hydrolysis rates of vitro fractions simulated GI, colonic fermentation freshly cooked Thai jasmine (control) by cooker method (RCM) boiling (BM), reheated stored for 3 days at 4 −20 °C are evaluated. Storage increased RS, slowly digestible (SDS) RCM, SDS BM due to the decrease rapidly (RDS). The effect differed with temperature. For GI conditions, 50.07%...

10.1002/star.201800049 article EN Starch - Stärke 2018-05-05

Riceberry is a new rice variety which has recently become popular in Thailand and Asia. Cooling cooked influences its digestion; however colonic fermentation studies comparing freshly (FCR), refrigerated (RR) frozen (FR) hydrolysates are limited. Here, vitro digestion rate of Thai riceberry prepared by conventional cooker (RCM) boiling method (BM), reheated after 3 days storage (4 C; RR -20 FR) were investigated. Starch fractions (% wet basis) differed between cooking methods due to varied...

10.15414/jmbfs.2018-19.8.3.940-946 article EN Journal of Microbiology Biotechnology and Food Sciences 2018-12-01

This study aimed to compare the effects of hydrolyzed copra meal (HCM) inclusion at 1% on its in vitro digestibility and microbiota cecum fermentation using gut weaned swine, targeting microbial community short-chain fatty acids (SCF). For this reason, three treatments were considered: control (no meal), non-hydrolyzed (CM), HCM. Non-defatted was analyzed (reducing sugars total carbohydrates) our laboratory. digestion, identification, assays, fresh fecal samples from two pigs (1 month old)...

10.3390/ani14111677 article EN cc-by Animals 2024-06-04

Amylases are among the most important enzymes with potential applications in present-day industry. Thus, isolating pure culture from cassava as cheap source has manifold importance for food industries. In present study, eleven amylase producing fungal strains were isolated flour and growth pattern, well optimum condition, was determined. All isolates showed amylases activity but isolate BR005, BR001 GR003 recorded maximum clear zone diameters of 54.75 ± 0.957 mm, 53.25 ±0.645 mm 51.5 1.414...

10.36547/ft.151 article EN Fungal Territory 2021-03-17
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