A5034510507- Probiotics and Fermented Foods
- Gut microbiota and health
- Microbial Metabolites in Food Biotechnology
- Enzyme Production and Characterization
- Protein Hydrolysis and Bioactive Peptides
- Biofuel production and bioconversion
- Animal Nutrition and Physiology
- Food composition and properties
- Digestive system and related health
- Microbial Metabolic Engineering and Bioproduction
- Ruminant Nutrition and Digestive Physiology
- Antimicrobial Peptides and Activities
- Nutritional Studies and Diet
- Diet and metabolism studies
- Clostridium difficile and Clostridium perfringens research
- Infant Nutrition and Health
- Pharmacological Effects of Natural Compounds
- Biopolymer Synthesis and Applications
- Microbial Inactivation Methods
- Listeria monocytogenes in Food Safety
- Meat and Animal Product Quality
- Polysaccharides and Plant Cell Walls
- Consumer Attitudes and Food Labeling
- Agriculture Sustainability and Environmental Impact
- Microencapsulation and Drying Processes
Kasetsart University
2016-2025
National Center for Genetic Engineering and Biotechnology
2011-2024
ActivBiotics (United States)
2021
EarthTech International (United States)
2014
University of Helsinki
1989-1991
VTT Technical Research Centre of Finland
1990
Abstract Asia differs substantially among and within its regions populated by diverse ethnic groups, which maintain their own respective cultures dietary habits. To address the diversity in gut microbiota, we characterized bacterial community fecal samples obtained from 303 school-age children living urban or rural five countries spanning temperate tropical areas of Asia. The microbiota profiled for subjects were classified into two enterotype-like clusters, each driven Prevotella (P-type)...
Abstract Background Extracellular metabolites of short chain fatty acids (SCFA) excreted by gut microbiota have been reported to play an important role in the regulation intestinal homeostasis. Apart from supplying energy, SCFA also elicit immune stimulation animal and human cells. Therefore, attempt was conducted isolate producing bacteria healthy microbiota. The anti-cancer anti-inflammatory effects extracellular individual SFCA were further investigated using breast, colon cancer...
Sugarcane bagasse pith is the most abundant agricultural waste in Thailand and an attractive raw material for biosugar production using dilute acid pretreatment enzymatic hydrolysis. In this study, was pretreated at 121 °C with different sulfuric concentrations (0%, 1%, 2%, 3% or 4% volume per volume, v/v) times (30, 60 90 min). The solid hydrolyzed a commercial enzyme (Celluclast® 1.5L). maximum total sugars yield (53.7 g/100 g dry pith) achieved 1–2% v/v H2SO4 min, representing 67% of...
The probiotic strain Lactobacillus reuteri KUB-AC5, which was originally isolated from chicken intestine, fed to newborn broiler chicks for the first week post-hatch. growth and ileum microbiota of chickens were carefully monitored 6 wk. inclusion 5 log cfu/g feed statistically increased BW gain in compared with that control group, but this effect did not continue thereafter. Significant effects on host consumption feed-to-growth conversion ratio detected. total amount composition bacteria...
Loss of traditional diets by food globalization may have adverse impact on the health human being through alteration gut microbial ecosystem. To address this notion, we compared microbiota urban (n=17) and rural (n=28) school-aged children in Thailand association with their dietary habits. Dietary records indicated that living Bangkok tended to consume modern high-fat diets, whereas Buriram vegetable-based diets. Sequencing 16S rRNA genes amplified from stool samples showed less...
This study focused on the characterization of mannanase from Bacillus circulans NT 6.7 for mannooligosaccharides (MOS) production. The enzyme B. was produced using defatted copra meal as a carbon source. purified by ultrafiltration and column chromatography Q-Sepharose. protein (M1) dimeric with 40 kDa subunit. M1 exhibited optimum pH temperature at 6.0 60 °C, respectively. It activated Mn2+, Mg2+, Cu2+, inhibited EDTA (45–65 %). high specificity to beta-mannan: konjac (glucomannan), locust...
Non-typhoidal salmonellosis (NTS) caused by multidrug-resistant (MDR) Salmonella enterica is a significant public health concern worldwide. Probiotics offer potential alternative to antibiotics in many infectious diseases, including NTS. However, using living bacteria raises safety concerns clinical settings, especially the immunocompromised host. This study compared anti-Salmonella and immunomodulatory effects between viable (probiotics) heat-killed (paraprobiotics) lactic acid...
Abstract A novel heterodimeric β‐galactosidase with a molecular mass of 105 kDa was purified from crude cell extracts the soil isolate Lactobacillus pentosus KUB‐ST10‐1 using ammonium sulphate fractionation followed by hydrophobic interaction and affinity chromatography. The electrophoretically homogenous enzyme has specific activity 97 U o NPG /mg protein. K m , k cat /K values for lactose ‐nitrophenyl‐β‐D‐galactopyranoside ( NPG) were 38 mM, 20 s ‐1 530 M ·s 1.67 540 325 000 respectively....
Poultry is an important high-quality food and protein source for humans. However, chicken considered a primary of foodborne diseases, especially Salmonella Enteritidis infection. Reducing contamination in live poultry will thus lower the risk to consumers. Our previous studies reported that Lactobacillus reuteri KUB-AC5 can produce substance with antimicrobial activity against pathogenic bacteria, Salmonella. In vivo testing revealed this strain greatly influenced ileal microbiota by...
Abstract A synbiotic is a combination of live microorganisms and specific substrates that are selectively utilized by host microorganisms, resulting in health benefits for the host. Previous studies have demonstrated protective effects L. reuteri KUB-AC5 against Salmonella infection chicken mouse models. The probiotic activity these hosts was influenced nutritional supplements. Water-based plants contain significant amounts carbohydrates, particularly dietary fiber proteins, making them...
Abstract The association between the gut mycobiome and its potential influence on host metabolism in Thai Cohort was assessed. Two distinct predominant enterotypes, Saccharomyces (Sa) Aspergillus / Penicillium (Ap/Pe) showed differences mycobiota diversity composition. Notably, Sa enterotype exhibited lower evenness richness, likely due to prevalence of , while both enterotypes displayed unique metabolic behaviors related nutrient body Fiber consumption positively correlated with adverse...
Summary Riceberry bran protein hydrolysate ( RBPH ) was prepared from of purple‐pigmented rice using enzymatic hydrolysis. The effect enzyme type (Alcalase, Flavourzyme and Neutrase) hydrolysis time (2, 4 6 h) on content, yield, total phenolic content TPC ), antioxidant activities ABTS FRAP molecular weight patterns investigated. significantly P < 0.05) affected the properties whereas had no significant ≥ those properties. most effective to increase compared Alcalase Neutrase. optimal...
Acute non-typhoidal salmonellosis (NTS) caused by Salmonella enterica Typhimurium (STM) is among the most prevalent of foodborne diseases. A global rising antibiotic resistance strains STM raises an urgent need for alternative methods to control this important pathogen. Major human food animals which harbor in their gut are cattle, swine, and poultry. Previous studies showed that probiotic Limosilactobacillus ( Lactobacillus ) reuteri KUB-AC5 (AC5) exhibited anti- activities chicken...
Exceeding a healthy weight significantly elevates the likelihood of developing type 2 diabetes (T2DM). A commercially available singular constituent, as either purified vitexin or iso-vitexin, has been associated with decreased risk T2DM, but its synergistic effect not reported yet. Vitexin and iso-vitexin were extracted using an ethanol-based solvent from mung bean seed coat (MBCE) subsequently preparative liquid chromatography (Prep-LC). Eleven mixture ratios and/or determined for their...
Summary High‐fat diets lead to fat accumulation and contribute the incidence of obesity, which has now become a global public health problem. directly impact microbial composition gastrointestinal tract, causing an imbalance in gut microbiota. This study investigated effect probiotics Limosilactobacillus reuteri KUB‐AC5 fermentum KUB‐D18 reducing negative effects associated with consumption high‐fat diet. Results metagenomics analysis demonstrated that regulated abundance Enterobacteriaceae...