Ming‐Ju Chen

ORCID: 0000-0003-4403-6112
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About
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Research Areas
  • Probiotics and Fermented Foods
  • Gut microbiota and health
  • Protein Hydrolysis and Bioactive Peptides
  • Microbial Metabolites in Food Biotechnology
  • Food composition and properties
  • Diet and metabolism studies
  • Meat and Animal Product Quality
  • Food Quality and Safety Studies
  • Microbial Metabolic Engineering and Bioproduction
  • Atomic and Subatomic Physics Research
  • Nuclear Materials and Properties
  • Digestive system and related health
  • Culinary Culture and Tourism
  • Fusion materials and technologies
  • Enzyme Production and Characterization
  • Vibrio bacteria research studies
  • Biofuel production and bioconversion
  • Clostridium difficile and Clostridium perfringens research
  • Characterization and Applications of Magnetic Nanoparticles
  • Ruminant Nutrition and Digestive Physiology
  • Milk Quality and Mastitis in Dairy Cows
  • Tryptophan and brain disorders
  • Dermatology and Skin Diseases
  • Food Allergy and Anaphylaxis Research
  • Infant Nutrition and Health

National Taiwan University of Science and Technology
2016-2025

National Taiwan University
2014-2025

Sichuan University of Science and Engineering
2022-2024

Northwestern Polytechnical University
2023-2024

First Affiliated Hospital of Guangdong Pharmaceutical University
2023

Guangdong Pharmaceutical University
2023

Chongqing Medical University
2022

The Affiliated Yongchuan Hospital of Chongqing Medical University
2022

Northeastern University
2019-2020

National Chung Hsing University
2020

Abstract Asia differs substantially among and within its regions populated by diverse ethnic groups, which maintain their own respective cultures dietary habits. To address the diversity in gut microbiota, we characterized bacterial community fecal samples obtained from 303 school-age children living urban or rural five countries spanning temperate tropical areas of Asia. The microbiota profiled for subjects were classified into two enterotype-like clusters, each driven Prevotella (P-type)...

10.1038/srep08397 article EN cc-by Scientific Reports 2015-02-23

This study was aimed at evaluating the antimutagenic and antioxidant properties of milk−kefir soymilk−kefir. Such activity determined by means Salmonella mutagenicity assay, whereas kefir were evaluated assessing 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity, lipid peroxidation inhibition ferrous ion chelating ability, reducing power, antioxidative enzyme activity. Both soymilk−kefir demonstrated significantly greater than milk soymilk. Milk−kefir also displayed scavenging...

10.1021/jf048934k article EN Journal of Agricultural and Food Chemistry 2005-03-02

Gut dysbiosis contributes to deterioration of chronic kidney disease (CKD). Probiotics are a potential approach modulate gut microbiota and gut-derived metabolites alleviate CKD progression. We aim provide comprehensive view CKD-related critical perspective on probiotic function in CKD. First, this review addresses microbial alterations during progression the adverse effects associated with changes metabolites. Second, we conduct thorough examination latest clinical trials involving...

10.1021/acs.jafc.4c00263 article EN cc-by Journal of Agricultural and Food Chemistry 2024-04-04

ABSTRACT: The purpose of this research was to improve probiotic microencapsulation using prebiotics and modern optimization techniques determine optimal processing conditions, performance, survival rates. Prebiotics (fructooligosaccharides or isomaltooligosaccharides), growth promoter (peptide), sodium algi‐nate were incorporated as coating materials microencapsulate 4 probiotics ( Lactobacillus acidophilus, Lacto‐bacillus casei, Bifidobacterium bifidum , longum ). proportion the prebiotics,...

10.1111/j.1365-2621.2005.tb09981.x article EN Journal of Food Science 2005-06-01

This study aimed to evaluate the hypocholesterolaemic property of milk-kefir and soyamilk-kefir. Male hamsters were fed on a cholesterol-free or cholesterol-enriched diet containing 10 % skimmed milk, milk-kefir, soyamilk soyamilk-kefir for period 8 weeks. The soyamilk, diets all tended towards lowering serum triacylglycerol total cholesterol concentrations, reduction accumulation in liver, decrease concentration being mainly non-HDL fraction. led significant increase faecal excretion...

10.1079/bjn20061752 article EN British Journal Of Nutrition 2006-04-11

Abstract: This study demonstrated that oral feeding of heat‐inactivated Lactobacillus (L b.) kefiranofaciens M1 from kefir grains effectively inhibited immunoglobulin (Ig) E production in response to ovalbumin (OVA) vivo . The pattern cytokine by splenocyte cells revealed the levels cytokines produced T helper (Th) 1 increased, and those Th2 decreased group. These findings indicated played an important role antiallergic activities. By additional analysis using flow cytometry microarray,...

10.1111/j.1750-3841.2010.01787.x article EN Journal of Food Science 2010-09-20

Scope Non‐alcoholic fatty liver disease (NAFLD) is a common that concomitant with obesity, resulting in increased mortality. To date, the efficiency of NAFLD treatment still needs to be improved. Therefore, we aimed evaluate effect Lactobacillus mali APS1, which was isolated from sugary kefir, on hepatic steatosis rats fed high‐fat diet (HFD). Methods and results Sprague Dawley were control diet, HFD saline, APS1 intervention by gavage daily for 12 weeks. The showed significantly reduced...

10.1002/mnfr.201700903 article EN Molecular Nutrition & Food Research 2018-03-06

Two probiotic strains, Lactobacillus johnsonii x-1d-2 and mucosae x-4w-1, originally isolated from piglet feces, have been demonstrated to possess antimicrobial activities, antibiotic resistances interleukin-6 induction ability in RAW 267.4 macrophages our previous study. These characteristics make L. x-4w-1 good candidates for application feed probiotics. In this study, soybeal meal, molasses sodium acetate were selected optimize the growth medium cultivation of x-4w-1. two strains then...

10.5713/ajas.14.0780 article EN cc-by Asian-Australasian Journal of Animal Sciences 2015-04-28

Gut dysbiosis is a major contributor to adverse chronic kidney disease (CKD) progression, and microbiota-based strategies could be considered as novel therapeutic preventative target. In this study, probiotic screening platform based on gut-derived uremic toxin-reducing probiotics was developed the underlying mechanism further verified through 0.2% adenine-induced CKD mouse model. Two strains (Lactobacillus paracasei Lactobacillus plantarum) were selected due their high clearance ability...

10.1021/acs.jafc.1c01547 article EN Journal of Agricultural and Food Chemistry 2021-06-25

Abstract The purpose of this research was to encapsulate Bifidobacterium bifidum using gellan, sodium alginate and prebiotics as coating materials, maximize the thermotolerance probiotics with an optimal combination materials. ratio materials for microparticles under heat treatments (75°C, 1 min) obtained by response surface method sequential quadratic programming technique. Optimization results indicated that 2% mixed 1% gellan gum would produce highest in terms B. count. verification...

10.1002/bit.21450 article EN Biotechnology and Bioengineering 2007-04-09

Lactobacillus kefiranofaciens M1 is a novel probiotic strain that was isolated from kefir grains. Previously, we have demonstrated the immunoregulatory, anti-allergic, anti-asthmatic and anti-colitis abilities of L. in number in-vitro in-vivo experiments. However, whether effects are elicited directly on host or act by regulating host's microbiota remains unknown. A studies used germ-free gnotobiotic animals to investigate relationship between probiotics colitis; therefore aim this study...

10.1371/journal.pone.0078789 article EN cc-by PLoS ONE 2013-11-11
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