A5021634320- Cerebral Palsy and Movement Disorders
- Hip disorders and treatments
- Foot and Ankle Surgery
- Lower Extremity Biomechanics and Pathologies
- Diabetic Foot Ulcer Assessment and Management
- Bone fractures and treatments
- Botulinum Toxin and Related Neurological Disorders
- Family and Disability Support Research
- Hip and Femur Fractures
- Balance, Gait, and Falls Prevention
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Infant Development and Preterm Care
- Tendon Structure and Treatment
- Muscle activation and electromyography studies
- Bone Tumor Diagnosis and Treatments
- Delphi Technique in Research
- Sarcoma Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Neurogenetic and Muscular Disorders Research
- Musculoskeletal Disorders and Rehabilitation
- Musculoskeletal synovial abnormalities and treatments
- Scoliosis diagnosis and treatment
- Nerve Injury and Rehabilitation
- Inclusion and Disability in Education and Sport
Nuffield Orthopaedic Centre
2016-2025
University of Oxford
2015-2025
Oxford Brookes University
2024
Oxford University Hospitals NHS Trust
2013-2023
British Society for Surgery of the Hand
2023
Marymount University
2023
Southampton Children's Hospital
2023
University of Southampton
2023
University of Liverpool
2023
Alder Hey Children's Hospital
2023
Muscle function often becomes progressively more compromised in children with spastic cerebral palsy, leading to reduced mobility. This study aimed examine the role that muscle connective tissue plays this process. Severity of spasticity as determined by a range clinical measures was assessed 26 (14 males 12 females; age 4 17 years) either diplegic or quadriplegic palsy (CP). biopsies from vastus laeralis were obtained for biomedical and histological analysis during orthopaedic surgery part...
Aims A national screening programme has existed in the UK for diagnosis of developmental dysplasia hip (DDH) since 1969. However, every aspect and treatment remains controversial. Screening programmes throughout world vary enormously, there is significant variation practice pathways. We report results an attempt by British Society Children’s Orthopaedic Surgery (BSCOS) to identify a nationwide consensus management DDH order unify suggest approach screening. Methods Delphi study was performed...
This study evaluated the efficacy and safety of three doses botulinum toxin A (BTX-A; Dysport) in 125 patients (mean age 5.2 years, SD 2; 54% male)with dynamic equinus spasticity during walking. Participants were randomized to receive Dysport (10, 20, or 30 units/kg) placebo gastrocnemius muscle both legs. Muscle length was calculated from electrogoniometric measurements change component shortening at four weeks prospectively identified as primary outcome measure. All treatment groups showed...
This study evaluated the efficacy and safety of three doses botulinum toxin A (BTX‐A; Dysport) in 125 patients (mean age 5.2 years, SD 2; 54% male)with dynamic equinus spasticity during walking. Participants were randomized to receive Dysport (10, 20, or 30 units/kg) placebo gastrocnemius muscle both legs. Muscle length was calculated from electrogoniometric measurements change component shortening at four weeks prospectively identified as primary outcome measure. All treatment groups showed...
Developmental dysplasia of the hip (DDH) is most common skeletal developmental disease. However, its genetic architecture poorly understood. We conduct largest DDH genome-wide association study to date and replicate our findings in independent cohorts. find heritable component attributable variants be 55% distributed equally across autosomal X-chromosomes. identify replicating evidence for between GDF5 promoter variation (rs143384, effect allele A, odds ratio 1.44, 95% confidence interval...
Muscle strengthening exercises are one of the interventions frequently prescribed by physiotherapists for adolescents with cerebral palsy (CP). However, there is wide variability in exercise regimes used and limited evidence their effectiveness. The ROBUST trial will assess clinical effectiveness an individually tailored programme, including progressive resistance advice, compared to usual care ambulant spastic CP. We conducting a multicentre, two-arm, parallel group, superiority randomized...
Cosmesis is important in the treatment of adolescent idiopathic scoliosis patients. The aim this study was to quantify cosmetic defect using parameters ISIS (Oxford Metrics Ltd., Oxford, England) scan. Ten nonmedical judges scored photographs 100 patients based on criteria. This Cosmetic Spinal Score proved be a reliable figure. then compared with and Cobb angle. An equation developed, which could predict sufficient reproducibility have useful clinical application. Bracing reduced rib hump...
The aim of this study was to define objectively gait function in children with treated congenital talipes equinovarus (CTEV) and a good clinical result. also attempted an analysis movement within the foot during gait. We compared 20 CTEV 15 control subjects. Clinical assessment demonstrated results from treatment. Three-dimensional provided kinematic kinetic data describing moments at joints lower limb A new method used on showed significantly increased internal rotation walking which...
We developed the Oxford ankle foot questionnaire to assess disability associated with and problems in children aged from five 16 years. A survey of 158 their parents was carried out determine content, scaling, reliability validity instrument. Scores can be calculated measure effect or on three domains children’s lives: physical, school play, emotional. for each domain were shown internally consistent, stable, vary little whether reported by child parent. Satisfactory face, content construct...
The effect of paediatric flexible flatfeet (PFF) on health-related quality life (HRQOL) has not been investigated. In this prospective cross-sectional study, the HRQOL children with PFF was compared to those typically developing feet (TDF) using two validated measures. We hypothesised that reduced would be observed in PFF. reliability parents' perceptions their child's symptoms also investigated.48 and 47 TDF between ages 8 15 completed Oxford Ankle Foot Questionnaire for Children (OxAFQ-C)...
e have assessed the reliability of four classification systems for club foot. Four observers evaluated nine children (18 feet) at different stages in first six months life, a total 180 examinations. Each observer independently all feet according to described by Catterall, Diméglio et al, Harrold and Walker, Ponseti Smoley. The variation between was using kappa test which no more agreement than chance has value 0, complete 1. values varied 0.14 0.77 depending on system used. al found greatest...
Muscle function often becomes progressively more compromised in children with spastic cerebral palsy, leading to reduced mobility. This study aimed examine the role that muscle connective tissue plays this process. Severity of spasticity as determined by a range clinical measures was assessed 26 (14 males 12 females; age 4 17 years) either diplegic or quadriplegic palsy (CP). biopsies from vastus laeralis were obtained for biomedical and histological analysis during orthopaedic surgery part...
Study Design. A retrospective study of 78 patients with right thoracic idiopathic scoliosis was done. Objectives. To evaluate the reliability Integrated Shape Imaging System scan (Oxford Metrics Ltd, Oxford, UK) in detecting progression and use back shape data predicting progression. Summary Background Data. At first presentation every 3-6 months during follow-up period, all underwent scans radiographic examinations, from which Cobb angle measured. The period 18-49 (mean = 31.4 months)....