A5008388820- Maternal and Perinatal Health Interventions
- Assisted Reproductive Technology and Twin Pregnancy
- Maternal and fetal healthcare
- Pregnancy and preeclampsia studies
- Neonatal Respiratory Health Research
- Maternal Mental Health During Pregnancy and Postpartum
- Birth, Development, and Health
- Ovarian function and disorders
- Palliative Care and End-of-Life Issues
- Ectopic Pregnancy Diagnosis and Management
- Gestational Diabetes Research and Management
- Neuroscience of respiration and sleep
- Reproductive Biology and Fertility
- Advances in Oncology and Radiotherapy
- Grief, Bereavement, and Mental Health
- Healthcare Policy and Management
- Reproductive System and Pregnancy
- Cerebral Palsy and Movement Disorders
- Child and Adolescent Health
- Preterm Birth and Chorioamnionitis
- Pregnancy and Medication Impact
- Congenital Diaphragmatic Hernia Studies
- Childhood Cancer Survivors' Quality of Life
- Cardiovascular Issues in Pregnancy
- Healthcare Operations and Scheduling Optimization
St Olav's University Hospital
2003-2022
Norwegian University of Science and Technology
2007-2021
Metformin is widely prescribed to pregnant women with polycystic ovary syndrome (PCOS) in an attempt reduce pregnancy complications. not approved for this indication, and evidence practice lacking.Our objective was test the hypothesis that metformin, from first trimester delivery, reduces complications PCOS.We conducted a randomized, placebo-controlled, double-blind, multicenter study at 11 secondary care centers.The participants were 257 PCOS, of pregnancy, aged 18-42 yr.We randomly...
Pregnancy implies delicate immunological balance between two individuals, with constant changes and adaptions in response to maternal capacity fetal demands. We performed cytokine profiling of 1149 longitudinal serum samples from 707 pregnant women map first trimester term beyond. The levels 22 cytokines C-reactive protein (CRP) followed diverse but characteristic trajectories throughout pregnancy, consistent staged adaptions. Eotaxin showed a particularly robust decrease pregnancy. A strong...
Abstract Background. The aim of this study was to assess the prevalence fear childbirth, and find possible associations selected sociodemographic factors important life events. A secondary explore relationship between these pregnancy outcome. Methods. Questionnaire booklets were sent 2680 women at 18 weeks gestation, whom 1452 (54%) responded. questionnaire included background (marital status, education, history abuse, current pregnancy), W‐DEQ (measurement childbirth), STAI subjective...
A pregnancy reaching 42 completed weeks (294 days) is defined as postterm (PT). The use of ultrasound in early for precise dating significantly reduces the number PT pregnancies compared to based on last menstrual period. Although fetal, maternal and neonatal risks increase beyond 41 weeks, there no conclusive evidence that prolongation pregnancy, per se, major risk factor. Other specific factors adverse outcomes have been identified, most important which are restricted fetal growth...
<b>Objective</b> To test the hypothesis that pre-eclampsia is a risk factor for cerebral palsy mediated through preterm birth and being born small gestational age. <b>Design</b> Population based cohort study. <b>Setting</b> Clinical data from Norwegian Cerebral Palsy Registry were linked with perinatal prospectively recorded by Medical Birth of Norway. <b>Participants</b> All singleton babies who survived neonatal period during 1996-2006 (849 children 616 658 control children). <b>Main...
In Brief OBJECTIVE: To compare induction of labor at gestational age 41 weeks with expectant management in regard to neonatal morbidity. Secondary aims were assess the effect these managements on mode delivery and maternal complications. METHODS: Between September 2002 July 2004, postterm women singleton cephalic presentation no prelabor rupture membranes randomly assigned 289 days or antenatal fetal surveillance every third day until spontaneous labor. Main outcome measures morbidity,...
In Brief OBJECTIVE: The aim of the study was to evaluate pregnancy outcomes by weeks gestation. A second assess in groups with spontaneous or induced labor. METHODS: This a prospective cohort singleton pregnancies delivered after 37 covering well defined region Norway from 1990 2001 (N = 27,514). Linear regression, χ2 tests, and multivariable logistic regression analysis were used. RESULTS: Maternal complications varied gestational age, lowest at 39 highest postterm (cesarean delivery...
Abstract Background. Clinical guidelines for post‐term management differ, and studies on women's attitudes are lacking. We aimed to assess the experiences among women managed with serial antenatal monitoring or induction of labor, effects pregnancy self‐reports quality life. Methods. Women were randomized at 41weeks immediate labor fetal surveillance every third day. At inclusion answered a questionnaire about their towards health‐related This was repeated in follow‐up phone interview...
Beyond term there is increased risk of intrauterine fetal death (IUFD) and perinatal death, we aimed to assess this beyond 41 weeks estimate numbers needed treat avoid 1 or neonatal death.All singletons births from 1999-2005 registered in the Norwegian Medical Birth Registry were assessed concerning IUFD day by day, induce was estimated.The rate with increasing gestational age. NNT for 527 at 287, 195 302 + (p-value=0.02). Routine induction labour implicates >14,000 inductions per year.NNT...
The aim of the present study was to assess indications for induction and describe characteristics delivery outcome in medical compared non-medical/elective inductions. During a three-month period, 1663 term inductions were registered 24 units Norway. Inclusion criteria singleton pregnancies with cephalic presentation at gestational age 37+0 beyond. Indications, pre-induction Bishop scores, mode adverse maternal fetal outcomes registered, between medically indicated elective groups. Ten...
Induction of labor has become more common in most countries during the last decade. We have compared methods and routines induction as practiced Norway 2003 2013, surveyed practices with regard to without a medical indication 2013.A telephone interview all delivery units was conducted 2003. Data on preferred methods, use prostaglandin, dosages, dose intervals routes administration were collected. In same questionnaire used, additional questions indication. overall cesarean section rates...
To evaluate whether insulin-like growth factor binding protein-1 (IGFBP-1) assessed in cervical secretion can predict successful induction and spontaneous onset of labor post-term pregnancy, compared to ultrasound measurement length Bishop score.Cohort study, originating from a randomized controlled trial.Obstetric department university tertiary referral hospital, Norway.Five hundred eight women who had been or expectant management 1 week beyond estimated day delivery (289 [±2] days...
To assess possible associations between androgen, estrogen and insulin levels blood pressure in pregnant women after term, compared with the effect of other well-known factors.Cross-sectional retrospective study.University Hospital, Trondheim region.Four hundred eighty-nine post-term uncomplicated pregnancies.Blood measurements fasting serum samples drawn one week beyond estimated day delivery (defined as 41(+2) weeks).Blood pressure, maternal age, body mass index, parity, smoking habits...
The aim of this study is to conduct an intervention that tests whether a new scheduling policy designed reduce waiting times actually will lead reduction in times. was developed using mixed methods. Qualitative data gathered fully understand current planning processes, while quantitative methods were used model and predict future If practices are continued, only increase. Additionally, the findings show simulation modeling can be capacity needed for intakes (first appointment) maintain...
Context: Metformin is widely prescribed to pregnant women with polycystic ovary syndrome (PCOS) in an attempt reduce pregnancy complications.Metformin not approved for this indication, and evidence practice lacking.Objectives: Our objective was test the hypothesis that metformin, from first trimester delivery, reduces complications PCOS.Design Setting: We conducted a randomized, placebocontrolled, double-blind, multicenter study at 11 secondary care centers.Participants: The participants...