- Balance, Gait, and Falls Prevention
- Cerebral Palsy and Movement Disorders
- Vestibular and auditory disorders
- Muscle activation and electromyography studies
- Sports injuries and prevention
- Ophthalmology and Eye Disorders
- Parkinson's Disease Mechanisms and Treatments
- Sports Performance and Training
- Stroke Rehabilitation and Recovery
- Injury Epidemiology and Prevention
- Tendon Structure and Treatment
- Lower Extremity Biomechanics and Pathologies
- Motor Control and Adaptation
- Effects of Vibration on Health
- Foot and Ankle Surgery
- Diabetic Foot Ulcer Assessment and Management
- Spine and Intervertebral Disc Pathology
- Ergonomics and Musculoskeletal Disorders
- Obstructive Sleep Apnea Research
- Biomedical Text Mining and Ontologies
- Spinal Fractures and Fixation Techniques
- Hip disorders and treatments
- Scoliosis diagnosis and treatment
- Older Adults Driving Studies
- Spatial Cognition and Navigation
Maastricht University Medical Centre
2016-2025
KU Leuven
2022-2025
Maastricht University
2014-2025
Centre Hospitalier de Luxembourg
2023
Laboratoire National de Santé
2023
German Sport University Cologne
2016-2020
University of Mohaghegh Ardabili
2018
London South Bank University
2018
University of Pittsburgh Medical Center
2017-2018
The University of Texas Southwestern Medical Center
2017
Abstract The relationship between the age-associated decline in mitochondrial function and its effect on skeletal muscle physiology remain unclear. In current study, we examined to what extent physical activity contributes health during aging compared young older adults, with similar habitual levels. We also studied exercise-trained adults physically impaired adults. Aging was associated a capacity, exercise capacity efficiency, gait stability, function, insulin sensitivity, even when...
The concept of the 'extrapolated center mass (XcoM)', introduced by Hof et al., (2005, J. Biomechanics 38 (1), p. 1–8), extends classical inverted pendulum model to dynamic situations. vector quantity XcoM combines position plus its velocity divided eigenfrequency. In this concept, margin stability (MoS), i.e., minimum signed distance from boundaries base support was proposed as a measure stability. Here we describe conceptual evolution XcoM, discuss key considerations in estimation and MoS,...
Background A combined vestibular (VI) and cochlear implant (CI) device, also known as the vestibulocochlear (VCI), was previously developed to restore both auditory function. new refined prototype is currently being investigated. This allows for concurrent multichannel stimulation. Although recent studies showed that VCI stimulation enables compensatory eye, body neck movements, constraints in these acute study designs prevent them from creating more general statements over time. Moreover,...
Reactive locomotor adaptations are crucial for safe mobility, but remain relatively unexplored. Here we assess reactive gait adaptations, and their retention, savings interlimb transfer. Using new methods to normalise walking speed perturbation magnitude, expose eighteen healthy adults ten unexpected treadmill belt accelerations during (the first last perturbing the right leg, others left leg) on two days, one month apart. Analysis of margins stability using kinematic data reveals that...
This study aimed to examine whether the triceps surae (TS) muscle-tendon unit (MTU) mechanical properties affect gait stability and its reactive adaptation potential repeated perturbation exposure in older adults. Thirty-four adults each experienced eight separate unexpected perturbations during treadmill walking, while a motion capture system was used determine margin of (MoS) base support (BoS). Ankle plantar flexor muscle strength Achilles tendon (AT) stiffness were analyzed using...
The plantarflexors play a crucial role in recovery from sudden disturbances to gait. objective of this study was investigate whether medium (months)- or long(years)-term exercise-induced enhancement triceps surae (TS) neuromuscular capacities affects older adults’ ability retain improvements reactive gait stability during perturbed walking acquired perturbation training sessions. Thirty-four adult women (65 ± 7 yr) were recruited group ( n = 13) that additionally completed 14 wk TS exercise...
Understanding balance and gait deficits in vestibulopathy may help improve clinical care our knowledge of the vestibular contributions to balance. Here, we examined walking speed effects on variability healthy adults with bilateral (BVP). Forty-four people BVP, 12 young older walked at 0.4 m/s 1.6 0.2 increments a dual belt, instrumented treadmill. Using motion capture kinematic data, means coefficients variation for step length, time, width double support time were calculated. The BVP group...
Abstract The ability to rapidly adjust gait cope with unexpected mechanical perturbations declines ageing. Previous studies, however, have not ensured that stability pre-perturbation was equivalent across participants or age groups which may influenced the outcomes. In this study, we investigate if age-related differences in following remain when all walk stability. We also examine interlimb transfer of adaptations are observed healthy older adults, by examining adaptation repeated one leg...
The concept of the 'extrapolated center mass (XcoM)', introduced by Hof et al. (2005, J. Biomechanics 38 (1), p. 1-8), extends classical inverted pendulum model to dynamic situations. vector quantity XcoM combines position plus its velocity divided eigenfrequency. In this concept, minimum distance from boundaries base support was proposed as a measure stability, i.e., margin stability (MoS). Here we describe conceptual evolution XcoM, discuss key considerations in measurement and MoS,...
Unilateral peripheral vestibular disorder (UPVD) causes deficient locomotor responses to novel environments due a lack of accurate sensory information, increasing fall risk. This study aimed examine recovery response (stability actions) and adaptive feedback potential in dynamic stability UPVD-patients healthy control subjects during perturbed walking. 17 (>6 months since onset) matched participants walked on treadmill were subjected eight unexpected perturbations the swing phase right leg....
Preserving upright stance requires central integration of the sensory systems and appropriate motor output from neuromuscular system to keep centre pressure (COP) within base support. Unilateral peripheral vestibular disorder (UPVD) causes diminished stability. The aim this study was determine limits stability examine contribution multiple standing in UPVD patients healthy subjects. We hypothesized that closure eyes Achilles tendon vibration during will augment postural sway more than...
An important goal in the treatment of osteoporotic vertebral compression fractures (OVCFs) is prevention new and subsequent progression to global sagittal malalignment. Current conservative multimodal comprises analgesics, medication for osteoporosis, physical therapy. However, little known about value orthoses OVCFs.The primary purpose this study was examine direct effect a semirigid thoracolumbar orthosis on gait patients suffering from an OVCF. The secondary evaluate changes gait,...
Given that falls most commonly occur during walking due to unexpected balance perturbations like trips and slips, walking-based assessment including stability adaptability such could be beneficial for fall risk in older adults. This cross-sectional study reanalyzed data from two larger studies conducted with the same protocol. Participants completed unperturbed trials at speeds of 0.4 m/s up 1.8 0.2 steps. Ten unannounced treadmill belt acceleration were then applied while participants...
Abstract Document recommendation systems for locating relevant literature have mostly relied on methods developed a decade ago. This is largely due to the lack of large offline gold-standard benchmark documents that cover variety research fields such newly search techniques can be compared, improved and translated into practice. To overcome this bottleneck, we established RElevant LIterature SearcH consortium consisting more than 1500 scientists from 84 countries, who collectively annotated...
Abstract Integration of accurate vestibular, visual, and proprioceptive information is crucial in managing the centre mass relation to base support during gait. Therefore, bilateral loss peripheral vestibular function can be highly debilitating when performing activities daily life. To further investigate influence an impaired system on gait stability, spatiotemporal parameters, step-to-step variability, mechanical stability parameters were examined 20 patients with vestibulopathy matched...
Scientists rely upon an accurate scientific literature in order to build and test new theories about the natural world. In past decade, observational studies of have indicated that numerous questionable research practices poor reporting may be hindering progress. particular, 3 recent implausibly high rate with positive (i.e., hypothesis confirming) results. sports medicine, a field closely related kinesiology, tested support for their primary ~70% time. However, study journals cover entire...