- Intracranial Aneurysms: Treatment and Complications
- Organic Electronics and Photovoltaics
- Conducting polymers and applications
- Vascular Malformations Diagnosis and Treatment
- Semiconductor materials and devices
- Advancements in Semiconductor Devices and Circuit Design
- Neuroscience and Neuropharmacology Research
- Perovskite Materials and Applications
- Memory and Neural Mechanisms
- Gut microbiota and health
- Integrated Circuits and Semiconductor Failure Analysis
- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Moyamoya disease diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Neurosurgical Procedures and Complications
- Probiotics and Fermented Foods
- Cerebrovascular and Carotid Artery Diseases
- Advanced Sensor and Energy Harvesting Materials
- Intracerebral and Subarachnoid Hemorrhage Research
- Clostridium difficile and Clostridium perfringens research
- Thin-Film Transistor Technologies
- Acute Ischemic Stroke Management
- Cerebrospinal fluid and hydrocephalus
Seoul National University
2016-2025
Institute for Basic Science
2023-2025
Nanchang University
2025
Third Affiliated Hospital of Nanchang University
2025
Korea Advanced Institute of Science and Technology
2021-2024
Seoul National University Bundang Hospital
2023
Government of the Republic of Korea
2020
University of Seoul
2010-2020
Hallym University
2018-2020
Seoul St. Mary's Hospital
2019
We evaluated immunometabolic functions of novel Lactobacillus fermentum strains (KBL374 and KBL375) isolated from feces healthy Koreans. The levels inflammatory cytokines, such as interleukin (IL)-2, interferon-γ, IL-4, IL-13, IL-17A, were decreased, that the anti-inflammatory cytokine IL-10 was increased, in human peripheral blood mononuclear cells (PBMCs) treated with L. KBL374 or KBL375 strain. When these orally administered to mice dextran sulfate sodium (DSS)-induced colitis, both...
Abstract The commercialization of organic solar cells (OSCs) requires both high power conversion efficiency (PCE) and long‐term stability. However, the lifetime OSCs containing small‐molecule acceptors (SMA) should be significantly enhanced. In this study, a series planarity‐controlled is developed, electron mobility dimerized SMAs (DSMAs) realize with high‐performance (PCE = 18.8%) high‐stability ( t 80% 5380 h under 1‐Sun illumination). An acetylene linker planar triple bond designed for...
Targeting the gut-liver axis by modulating gut-microbiome can be a promising therapeutic approach in nonalcoholic fatty liver disease (NAFLD). The aim of this study was to evaluate effects single species and combination Lactobacillus Pediococcus NAFLD mice model. Six-week male C57BL/6J were divided into 9 groups (n = 10/group; normal, Western diet, 7 diet-strains [109 CFU/g, 8 weeks]). strains used L. bulgaricus, casei, helveticus, P. pentosaceus KID7, three combinations (1: casei+L. 2:...
Small-molecule acceptor (SMA)-based organic solar cells (OSCs) have achieved high power conversion efficiencies (PCEs), while their long-term stabilities remain to be improved meet the requirements for real applications. Herein, we demonstrate use of donor-acceptor alternating copolymer-type compatibilizers (DACCs) in high-performance SMA-based OSCs, enhancing PCE, thermal stability, and mechanical robustness simultaneously. Detailed experimental computational studies reveal that addition...
Objective: The purpose of this study was to present the computed tomography (CT) findings pulmonary artery sarcoma in 7 patients with a focus on distinguishing features embolic disease. Methods: For 9 years from December 1993 November 2002, we treated pathologically proven sarcoma, and during 2 2000 40 acute (n = 33) or chronic 7) embolism. In these patients, embolism diagnosed serial CT clinical findings. Two chest radiologists, blinded diagnoses, independently reviewed scans all 47 random...
Color and Power Doppler Twinkling Artifacts from Urinary StonesClinical Observations Phantom StudiesJae Young Lee1, Seung Hyup Kim1, Jeong Yeon Cho2 Daehee Han1Audio Available | Share
Adequate management of increased intracranial pressure (ICP) is critical in patients with traumatic brain injury (TBI), and decompressive craniectomy widely used to treat refractory ICP. The authors reviewed analyzed complications following for the TBI.A total 89 consecutive who underwent TBI between February 2004 2009 were retrospectively. Incidence rates secondary determined, analyses performed identify clinical factors associated development poor outcome.Complications occurred 48 (53.9%)...
<italic>L. acidophilus</italic>treatment can modulate immune responses, control the micro-RNA levels and restore gut microbiota of mice with DSS-induced colitis. Therefore,<italic>L. could be useful to inflammatory bowel diseases.
Administration of probiotics has been linked to immune regulation and changes in gut microbiota composition, with effects on atopic dermatitis (AD). In this study, we investigated amelioration the symptoms AD using
Abstract Polythiophenes (PTs) have attracted considerable interest for application in organic solar cells (OSCs) owing to their simple molecular structures and low‐cost synthesis. However, the power conversion efficiencies (PCEs) of PT‐based OSCs are lower than those state‐of‐the‐art OSCs. Herein, development two sequentially fluorinated PT donors (PT‐2F PT‐4F) is reported realizing highly efficient PT‐2F PT‐4F designed contain four fluorine atoms, respectively, per repeating unit decrease...
Abstract Despite the potential of ternary polymer solar cells (PSCs) to improve photocurrents, architecture is not widely utilized for PSCs because its application has been shown reduce fill factor (FF). In this paper, a novel technique reported achieving highly efficient without characteristic sharp decrease in FF by matching highest occupied molecular orbital (HOMO) energy levels two donor polymers. Our device—made from blend wide‐bandgap...
Activity-dependent changes in the number of AMPA-type glutamate receptors (AMPARs) at synapse underpin expression LTP and LTD, cellular correlates learning memory. Post-translational ubiquitination has emerged as a key regulator trafficking surface AMPARs, with GluA1 subunit Lys-868 controlling post-endocytic sorting into late endosome for degradation, thereby regulating their stability synapses. However, physiological significance remains unknown. In this study, we generated mice knock-in...
✓ Cerebral sparganosis is a rare parasitic disease caused by infestation the plerocercoid larva of Spirometra mansoni . The authors retrospectively analyzed 17 cases cerebral treated at Seoul National University Hospital between 1986 and 1994. patients' ages diagnosis ranged from ± to 57 years (median 32 years) male/female ratio was 13:4. Diagnosis based on radiological findings, serological test results, operative histopathological examinations. Characteristic magnetic resonance (MR)...
The systematic variation of magnetic permeability and dielectric constant their relationship with microwave absorbing properties are investigated in sintered Ni-Zn ferrite. Toroidal compacts (Ni/sub 1-x/Zn/sub x/O)(Fe/sub 2/O/sub 3/)spinels were prepared by conventional ceramic processing technique. large change is observed the zinc content (x) spinel lattice. High can be obtained sintering samples nitrogen (reducing) atmosphere. A combination high loss results a thin ferrite-tile absorber...
✓ The authors present the clinical, radiological, pathological features, and autopsy findings of a patient with malignant triton tumor acoustic nerve, which probably arose from pre-existing schwannoma. term “malignant tumor” is applied to schwannomas rhabdomyoblastic differentiation. A cerebellopontine angle spinal drop metastasis occurred in this 10 months after near-total removal original tumor.
To identify differences in the clinical, radiologic, and microbiologic features of pulmonary tuberculosis (TB) young (<64 yr) elderly (> or =65 yr), we performed a retrospective analysis medical charts chest radiographs 207 119 TB patients. Hemoptysis febrile sense were more frequent young, whereas weakness, dyspnea, anorexia, mental change elderly. Elderly patients showed higher frequencies cardiovascular chronic lung diseases, proportion underlying liver disease. In addition, radiography...