A5055974608- Primate Behavior and Ecology
- Animal Behavior and Reproduction
- Neuroendocrine regulation and behavior
- Stress Responses and Cortisol
- Neurogenesis and neuroplasticity mechanisms
- Animal Vocal Communication and Behavior
- Nerve injury and regeneration
- Endometrial and Cervical Cancer Treatments
- Neuroscience and Neuropharmacology Research
- Ovarian cancer diagnosis and treatment
- Hypothalamic control of reproductive hormones
- Molecular Biology Techniques and Applications
- Axon Guidance and Neuronal Signaling
- Forensic and Genetic Research
- Hormonal and reproductive studies
- Parkinson's Disease Mechanisms and Treatments
- Reproductive System and Pregnancy
- Metabolism and Genetic Disorders
- Pregnancy and preeclampsia studies
- Sperm and Testicular Function
- Cervical Cancer and HPV Research
- Neuropeptides and Animal Physiology
- Cancer Research and Treatments
- Paraquat toxicity studies and treatments
- Evolutionary Psychology and Human Behavior
Asahikawa Medical University
2014-2024
Okayama University of Science
2011-2023
Okayama University
1992-2023
Kitasato University
2016-2020
Okayama Rosai Hospital
2020
Kyorin University
2017
Tokyo University of Marine Science and Technology
2014
Tokai University
1995-2013
Social Welfare Organization Saiseikai Imperial Gift Foundation
1998-2013
University of California, Berkeley
2013
In wildlife populations, group-living is thought to increase the probability of parasite transmission because contact rates at high host densities. Physical contact, such as social grooming, an important component group structure, but it can also risk exposure infection for individuals provides a mechanism potentially pathogenic organisms. Living in groups create variation susceptibility among circulating levels immunosuppressive hormones like glucocorticoids often depend on individual's...
Senile plaques (SPs) containing amyloid β peptide (Aβ) 1-42 are the major species present in Alzheimer disease (AD), whereas Aβ1-40 is constituent of arteriolar walls affected by cerebral angiopathy. The water channel proteins astrocytic aquaporin 1 (AQP1) and 4 (AQP4) known to be abnormally expressed AD brains, but expression AQPs surrounding SPs angiopathy has not been described detail. Here, we investigated whether AQP associated with each Aβ deposited human brains either sporadic or...
Peroxynitrite can nitrate tyrosine residues of proteins. We examined nitrotyrosine-containing proteins in cerebrospinal fluid 66 patients with neurogenic disease by immunoblot analysis. Nitrated residue-containing protein was observed the and concluded to be manganese superoxide dismutase (Mn-SOD). The nitrated Mn-SOD level strikingly elevated amyotrophic lateral sclerosis slightly increased Alzheimer's Parkinson's patients, whereas an only progressive supranuclear palsy group.
We previously reported the isolation of a cDNA encoding liver-specific isozyme rat S-adenosylmethionine synthetase from lambda gt11 liver library. Using this as probe, we have isolated and sequenced clones for kidney (extrahepatic isoenzyme) The complete coding sequence enzyme mRNA was obtained two overlapping clones. amino acid deduced cDNAs indicates that contains 395 acids has molecular mass 43,715 Da. predicted protein shares 85% similarity with synthetase. This result suggests...
Colchicine binds to intracellular tubulin and prevents mitosis. is also used as an anti-inflammatory drug. Meanwhile, excess administration of medication or accidental ingestion colchicine-containing plants can cause acute colchicine poisoning, which initially results in gastrointestinal effects that may be followed by multiorgan dysfunction. However, the mechanism poisoning remains unclear, there are no standard therapeutic strategies. We focused on intestinal barrier function attempted...
The operational sex ratio (OSR) is used as a predictor for the intensity of mating competition. While many factors affect OSR, there tends to be high male bias in primate species with long interbirth intervals and non-seasonal breeding, such hominid apes. However, OSR bonobos (Pan paniscus) lower than that chimpanzees troglodytes), which thought reduce competitive aggressive behaviors. low considered result from early resumption female sexual receptivity during postpartum infertility they...
To examine a relation between the production of acetylcholine-induced endothelium-derived contracting factor and an increase in blood pressure, endothelium-dependent contraction relaxation were evaluated by measuring isometric tension aortic rings from spontaneously hypertensive rats Wistar-Kyoto at 5, 10, 20, 30 weeks age. In norepinephrine-precontracted rings, acetylcholine (10(-8) to 10(-5) M)-induced relaxations diminished doses 10(-6) M both strains except 5 Treatment with thromboxane...
Because cellular atypia is often limited in endometrial hyperplasia and well-differentiated adenocarcinoma (WHO Grade 1 adenocarcinoma), diagnostic criteria for cytology have not been fully established. New based on the composition architecture of tissue fragments (cytoarchitecture) smears were used present study. Cytologic features are less importance because distinction between relies more architectural than changes. Cell clumps various size usually collected abundantly with cytologic...
<b><i>Objective:</i></b> To evaluate the sensitivity and specificity of endometrial cytology obtained by intrauterine sample using a descriptive reporting format for cytological diagnosis. <b><i>Study Design:</i></b> 10,152 consecutive scrapings in 13 different Japanese hospitals were analyzed. Cytological results classified as ‘negative malignancy’, ‘atypical cells’ (ATEC), ‘endometrial hyperplasia’, hyperplasia’ or ‘malignant tumor’. ATEC was...
Japanese macaques inhabit a relatively cold environment and females of this species could have developed strategies energy economy to face the sometimes-harsh seasonal conditions temperate climates, as well reproductive costs, thus regulate their balance. Here, we explore relationship between nutritional status, body composition, seasonality, status using isotope-labeled water, anthropometric measurements, leptin assays from 14 captive female macaques. Our results indicated that mass...
The capacity for reproduction in germfree mice remain inferior to their conventional counterparts even after improvement of feed and other such rearing conditions. authors provide evidence increased reproductive following association with bacteria. Estrous cycles were normalized female accidentally contaminated bacteria, given fecal suspensions the per os. Significant rises seen copulation implantation rates, reaching levels comparable values mice. In male mice, bacterial contamination...