A5088984897- Leptospirosis research and findings
- Prostate Cancer Diagnosis and Treatment
- Viral Infections and Vectors
- Urologic and reproductive health conditions
- Prostate Cancer Treatment and Research
- Renal cell carcinoma treatment
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Urinary and Genital Oncology Studies
- Genital Health and Disease
- Histiocytic Disorders and Treatments
- Systemic Lupus Erythematosus Research
- Tumors and Oncological Cases
- Veterinary medicine and infectious diseases
- Parasites and Host Interactions
- Urological Disorders and Treatments
- Sarcoma Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- Cancer Genomics and Diagnostics
- Immunotherapy and Immune Responses
- Radiomics and Machine Learning in Medical Imaging
- Mycobacterium research and diagnosis
- Research on Leishmaniasis Studies
- Bone Tumor Diagnosis and Treatments
Universidade Federal da Bahia
2015-2024
Complexo Hospitalar Universitário Professor Edgard Santos
2002-2024
Centrus Diagnósticos por Imagem
2019-2023
Fundação Oswaldo Cruz
2008-2021
Hospital Ana Nery
2012-2021
Queen's University
2018
University of Calgary
2016-2017
Calgary Laboratory Services
2016-2017
Rockyview General Hospital
2017
Ministério da Saúde
2006-2012
Eosinophilic solid and cystic renal cell carcinoma (ESC RCC) has been recently described as a unique indolent neoplasm, found in female patients with without tuberous sclerosis complex. Although ESC RCC distinct morphology frequent CK20 reactivity, its molecular karyotype previously studied only few cases. We identified 19 from multiple institutions; all were individuals clinical features of Molecular karyotyping was performed 13 cases (12 informative result). The median age 55 years (range:...
To ascertain prognostic factors associated with fatal outcomes in severe leptospirosis, a retrospective case-control study was done using population-based surveillance data. Centralized death certificate reporting of leptospirosis mortality combined details patients’ hospitalizations, which were obtained from hospitals representing all sectors São Paulo city. Among identified cases, 89 lethal cases and 281 survivor analyzed. Predictors included age > 40 years, development oliguria,...
Neglected tropical diseases, including zoonoses such as leptospirosis, have a major impact on rural and poor urban communities, particularly in developing countries. This has led to investment antipoverty vaccines that focus diseases influence public health thereby productivity. While the true, global, of leptospirosis is unknown due lack adequate laboratory diagnosis, WHO estimates incidence doubled over last 15 years 1 million cases require hospitalization every year. Leptospirosis caused...
Aims To evaluate concordance, upgrades and downgrades from biopsy to prostatectomy, associated clincopathological parameters, using the recently proposed Gleason grade groups/International Society of Urologic Pathology ( ISUP ) grades. Methods results We evaluated 2529 patients who underwent prostatectomy in our institution 2005 2014. A global group GR )/Gleason score GS was used. Factors with 1/ ≤6 2/ 3 + 4 were analysed by multivariable logistic regression. The final / identical 59.3%...
Abstract Classification of renal cell carcinomas has become more challenging. The 2016 WHO classification included 14 different subtypes and 4 emerging/provisional entities, recent literature indicates new entities to be incorporated. Nomenclature is based on cytoplasmic appearance, architecture, combination morphologies, anatomic location, underlying disease, familial syndromes, specific genetic alterations. Immunohistochemistry useful in selected cases while it can insufficient that...
To further characterise biphasic squamoid renal cell carcinoma (RCC), a recently proposed variant of papillary RCC.We identified 28 tumours from multiple institutions. They typically showed two populations-larger cells with eosinophilic cytoplasm and higher-grade nuclei, surrounded by smaller, amphophilic scanty cytoplasm. The dual morphology was variable (median 72.5% tumour, range 5-100%); emperipolesis found in all cases. male/female ratio 2:1, the median age 55 years (range 39-86 years)....
Abstract Background : Anti‐C1q antibodies have been described in systemic lupus erythematosus (SLE) as well other connective tissue diseases. They considered a marker for disease activity and presence of nephritis. Objective The aim this study was to determine the prevalence anti‐C1q Brazilian patients analyze their association with different clinical serologic parameters. Methods Sera from 81 SLE patients, based on American College Rheumatology (ACR) criteria, were collected referral...
The mouse disease model has the advantage of a broad array immunological and genetic tools available for basic research. Some studies on transgenic and/or mutant strains as models experimental leptospirosis have been reported; however, wider use such is hampered by poor understanding outcome leptospiral infection among different available. Here, virulent strain Leptospira interrogans serogroup Icterohaemorrhagiae Cop was studied in four commonly used wild-type strains: A, CBA, BALB/c...
Leptospirosis is a zoonotic disease that causes severe manifestations such as Weil's and pulmonary hemorrhage syndrome. The aim of this study was to evaluate whether reactive oxygen species (ROS) production antioxidant reduced glutathione (GSH) levels are related complications in patients hospitalized with leptospirosis. ROS GSH were measured blood samples 12 nine healthy controls using chemiluminescence absorbance assays. We found higher lower leptospirosis compared individuals. Among...
This manuscript summarizes the first part of proceedings 2023 Dublin ISUP Consensus Conference encompassing best practice recommendations on pathology neoplasms urachal origin. The rationale for convening this consensus conference was lack structured and consented histopathologic in these rare tumors. among meeting participants (n=80) reached following statements: (1) combination gross, histologic, clinical imaging findings with exclusion secondary tumor metastasis are to be used diagnosis...
ABSTRACT The aims of this study were to investigate the frequency pulmonary hemorrhage (PH) in mice unable produce functional B and T lymphocytes explore effect an inducible nitric oxide synthase gene ( Inos ) knockout (KO) on frequency/severity interstitial nephritis vivo . We studied outcome infection by virulent Leptospira interrogans serovar Copenhageni strain Cop. animals used KO mice, recombination activating 1 Rag1 CB17 severe combined immunodeficiency (SCID) respective wild-type (WT)...