A5021663095- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
- Diagnosis and Treatment of Venous Diseases
- Vascular Procedures and Complications
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Central Venous Catheters and Hemodialysis
- Infectious Aortic and Vascular Conditions
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Vascular anomalies and interventions
- Angiogenesis and VEGF in Cancer
- Aortic Disease and Treatment Approaches
- Nutrition and Health Studies
- Dermatologic Treatments and Research
- Systemic Sclerosis and Related Diseases
- Atherosclerosis and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- S100 Proteins and Annexins
- Gallbladder and Bile Duct Disorders
- Cancer, Lipids, and Metabolism
- Renal and Vascular Pathologies
- Psoriasis: Treatment and Pathogenesis
- Lipoproteins and Cardiovascular Health
- Sympathectomy and Hyperhidrosis Treatments
Medical University of Lublin
2015-2024
Medical University of Silesia
2021
Instytut Medycyny Wsi im. Witolda Chodźki
2018
Duke University
2017
Yale University
2017
Humacyte (United States)
2017
1 Military Clinical Hospital with Outpatient Clinic
2014
This review article discusses the utility of 18F-FDG PET/CT in diagnosis and management vascular disease. We stress usefulness this method large vessel inflammation infection. In our work we based on literature analysis clinical cases diagnosed institution by use PET/CT. The exploration was focusing infections 18-FDG PET. search performed PubMed database cross referencing. present practical with several images diseases like: Takayasu arteritis, giant cell graft infections, abdominal aortic...
Diosmin is a natural compound with wide range of biological activity, e.g., it improves lymphatic drainage, supports microcirculation, and increases venous tone, elasticity, hence, applied in the pharmacotherapy chronic disorders (CVD). The aim this study was to assess correlation between diosmin administration (2 × 600 mg daily) patients suffering from CVD levels selected factors influencing angiogenesis, which are involved pathophysiology. Thirty-five were examined. Levels plasma tumor...
Patients with end stage renal failure who require haemodialysis suffer morbidity and mortality due to vascular access. Bioengineered human acellular vessels (HAVs) may provide a access option fewer complications than other grafts. In prospective phase II trial from 2012 2014 (NCT01744418), HAVs were implanted into 40 patients at three sites in Poland. The protocol for this "first man" use of the HAV contemplated only two years follow up, results initially reported 2016. light retained...
Oxidative stress plays an important role in the pathophysiology of many human disorders, while antioxidants prevent development various adverse symptoms. Diosmin is a natural flavonoid applied vascular system especially chronic venous insufficiency (CVI), and it significant part alleviation CVI Due to antioxidant activity, also has ability scavenge oxygen free radicals hence decreases level oxidative biomarkers, such as prostaglandins their precursors—isoprostanes. In study, influence...
Atherosclerosis and it's comorbidities are the major contributors to global burden of death worldwide. Lower extremities arterial disease (LEAD) is a common manifestation atherosclerotic arteries lower extremities. MicroRNAs belong epigenetic factors that regulate gene expression have not yet been extensively studied in LEAD. We aimed indicate most promising microRNA signatures disease, identify interactions between genes describe potential effect modulated expression. High-throughput...
The human acellular vessel (HAV) was evaluated for surgical bypass in a phase II study. primary results at 24 months after implantation have been reported, and the patients will be ≤10 years. In present report, we described 6-year of prospective, open-label, single-treatment arm, multicenter Patients with advanced peripheral artery disease (PAD) requiring above-the-knee femoropopliteal surgery without available autologous graft options had undergone HAV, bioengineered tissue replacement...
Chronic venous disease (CVD) is a vascular of lower limbs with high prevalence worldwide. Pathologic features include varicose veins, valves dysfunction and skin ulceration resulting from cell proliferation, apoptosis angiogenesis. These processes are partly regulated by microRNA (miRNA)-dependent modulation gene expression, pointing to miRNA as potentially important target in diagnosis therapy CVD progression. The aim the study was analyze alterations expression CVD, well identify...
Abdominal artery aneurysm (AAA) refers to abdominal aortic dilatation of 3 cm or greater. AAA is frequently underdiagnosed due often asymptomatic character the disease, leading elevated mortality rupture. MiRNA constitute a pool small RNAs controlling gene expression and involved in many pathologic conditions human. Targeted panel detecting altered miRNA genes would improve early diagnosis this disease. In presented study, we selected analyzed signatures patients. Next, generation sequencing...
The 2017 Polish Consensus Statement (PCS 2017) includes updated recommendations on the prevention, diagnostic approach, and management of venous thromboembolism (VTE). For VTE without cancer, authors PCS recommend apixaban, edoxaban, rivaroxaban, dabigatran over vitamin K antagonists (VKA) as long-term anticoagulant therapy. with low molecular weight heparins (LMWH) VKA, rivaroxaban dabigatran. extended secondary prevention deep thrombosis (DVT), recommends dabigatran, sulodexide. pulmonary...
Introduction: The aim of the study was to evaluate efficacy endovascular ablation method GSV/ /SSV superficial venous insufficiency using Flebogrif® catheter, safety method, expressed in number and quality observed complications 24-month observation. Material methods: Initially, group included 200 patients undergoing insufficient GSV/SSV. During 24 months observation, this decreased 158, which seems be a natural process. All signed informed consent form approved by Bioethics Committee...
BACKGROUND: 18F-FDG PET/CT has become an important tool in diagnosis of prosthetic vascular graft infections (PVGI). The aim the study was to identify patterns infection PET/CT. MATERIAL AND METHODS: performed 24 patients with infection, 17 implanted open surgery mode and 7 by endovascular aortic repair (EVAR). Vascular prostheses were evaluated two visual scales semi-quantitative analysis maximum standardized uptake values (SUV max). RESULTS: In 3-point scale: 23 grade 1 one patient 2....
Objective Our objective was to evaluate the state of oxidative stress in great saphenous varicose vein wall and blood patients taken from antecubital vein. Methods The superoxide dismutase, reduced glutathione (GSH) total antioxidant status were measured with commercially available colorimetric kits erythrocytes, plasma 65 (second degree clinical classification, etiology, anatomy pathophysiology) aged 22-70 (49 women, 16 men) comparison normal walls collected 10 who underwent coronary artery...
Purpose: To evaluate the safety and performance of Treovance stent-graft. Methods: The global, multicenter RATIONALE registry ( ClinicalTrials.gov; identifier NCT03449875) prospectively enrolled 202 patients (mean age 73.0±7.8 years; 187 men) with abdominal aortic aneurysms (AAA) suitable for endovascular aneurysm repair (EVAR) using Treovance. composite primary endpoint was site-reported all-cause mortality major morbidity. efficacy outcome clinical success. Further outcomes evaluated...
Food Effect on LDL-C Foods high in n-6 PUFA and/or MUFA and low SFA; e.g., canola oil Moderate to large reduction soluble fiber; psyllium, oats, barley with added plant sterols or stanols Flaxseeds (whole) Small moderate Soy protein Tomatoes Almonds Fish No clear effect Decaffeinated coffee (in place of regular coffee) Filtered SFA trans fatty acids (i.e., solid tropical fats) increase Unfiltered filtered Avocados Turmeric Hazelnuts Pulses Green tea At least small Fiber, whole grains Walnuts...
Introduction. Chronic venous insufficiency is one of the most common medical conditions among highly developed societies. The majority patients (70%) suffer from saphenous veins incompetency. study presents results a 3-month follow-up application mechanochemical ablation system with FlebogrifTM catheter. Material and methods. was conducted on 200 patients, including 170 women 30 men treated to treat varicose veins. All were qualified based ultrasound in standing position confirming...
Psoriasis is a common, chronic immune-mediated multifactorial skin disease. In its pathogenesis altered differentiation and hyperproliferation of keratinocytes, dysregulation immunological cell functions, together with abnormal angiogenesis are involved. Angiogenesis defined as the formation new blood vessels from pre-existing vascular bed. This complex multistep process regulated by different factors among which endothelial growth factor (VEGF) considered to be most important. The aim this...
Abstract The infection of a vascular prosthesis is potentially fatal, and its effective treatment still remains the greatest challenge for surgeons. We present our initial experience using bovine pericardial prostheses to replace infected aortoiliac grafts. Six consecutive patients with graft were prospectively included in this study. Infection was confirmed by clinical symptoms, laboratory tests results computed tomography positron emission tomography/computed tomography. In all cases,...
Introduction: Carotid endarterectomy (CEA) is a surgical procedure used in the prevention of ischemic stroke. However, this can cause complications ischemia-reperfusion injury to brain. Clusterin (CLU) cytoprotective chaperone protein that released from neurons response various neurological injuries. The objective study was report changes serum CLU concentrations patients undergoing CEA. Materials and methods: involved 25 with severe internal carotid artery stenosis. Serum samples were taken...
Abstract Background Increased blood pressure in the varicose veins (VV) can contribute to overexpression of matrix metalloproteinases (MMPs), affecting endothelium, smooth muscle, and extracellular vein wall. Gelatinases (MMP-2 MMP-9), hypoxia, inflammation occurring VV wall increased expression vascular endothelial growth factor (VEGF). Aims Our objective was analyze concentration gelatinases VEGF great saphenous plasma patients. Methods In total, 65 patients (2nd degree according clinical...