A5100627351- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological Disease Mechanisms and Treatments
- Acute Ischemic Stroke Management
- Cerebrospinal fluid and hydrocephalus
- Acupuncture Treatment Research Studies
- EEG and Brain-Computer Interfaces
- Cerebrovascular and Carotid Artery Diseases
- Enzyme-mediated dye degradation
- Glaucoma and retinal disorders
- interferon and immune responses
- Retinopathy of Prematurity Studies
- Neurogenesis and neuroplasticity mechanisms
- Advanced Cellulose Research Studies
- Genetics and Neurodevelopmental Disorders
- Neurological disorders and treatments
- Gut microbiota and health
- Infectious Encephalopathies and Encephalitis
- Biofuel production and bioconversion
- Cerebrovascular and genetic disorders
- Healthcare and Venom Research
- Pluripotent Stem Cells Research
- Bipolar Disorder and Treatment
- Treatment of Major Depression
- Thyroid Disorders and Treatments
- Biochemical and biochemical processes
Capital Medical University
2021-2025
National Clinical Research Center for Digestive Diseases
2021-2025
Beijing Tian Tan Hospital
2021-2025
Shanghai University of Traditional Chinese Medicine
2024
Yueyang Hospital
2024
Xiamen University
2024
Beijing Children’s Hospital
2024
Chinese Institute for Brain Research
2021-2023
Sichuan Agricultural University
2020-2023
Chengdu University
2020
Lignin–xylan hybrid nanospheres prepared by self-assembly is a smart material platform for pesticide encapsulation and enzyme-mediated release.
ABSTRACT Background and Objectives The relationship of cardiac function with cerebral small vessel disease (CSVD) remains unknown. study aimed to investigate the association between left ventricular (LV) CSVD in a community‐based population. Methods Community‐dwelling residents China from cross sectional survey PRECISE (PolyvasculaR Evaluation for Cognitive Impairment vaScular Events) cohort were included. LV ejection fraction (LVEF) fractional shortening (LVFS) measured systolic function,...
Cerebral small vessel disease (CSVD) is a significant burden of morbidity and mortality among elderly people around the world. Epidemiological data with complete CSVD evaluations large sample size in general population are still limited.Community-dwelling residents Lishui city China from cross-sectional survey Polyvascular Evaluation for Cognitive Impairment Vascular Events (PRECISE) study were included this 2017 to 2019. All participants underwent 3 Tesla brain magnetic resonance images...
Background: High plasma levels of trimethylamine N-oxide (TMAO) and its precursor choline have been linked to stroke; however, their association with cerebral small vessel disease remains unclear. Here we evaluated the TMAO imaging markers disease, including white matter hyperintensities, lacunes, microbleeds. Methods: We performed a baseline cross-sectional analysis multicenter hospital-based cohort study from 2015 2018. The data were collected 30 hospitals in China included 1,098 patients...
Similar white matter hyperintensities (WMH) burden may have varied cognitive outcomes in patients with cerebral small vessel disease (CSVD). This study aimed to evaluate whether blood-brain barrier (BBB) permeability is associated impairment (CI) heterogeneity WMH.We recruited 51 participants WMH. We evaluated WMH using the Fazekas scale and volume on structural magnetic resonance imaging (MRI), assessed BBB dynamic contrast-enhanced (DCE)-MRI. used permeability-surface area product (PS)...
Abstract INTRODUCTION Oculomotor and gait dysfunctions are closely associated with cognition. However, oculo‐gait patterns their correlation cognition in cerebral small vessel disease (CSVD) remain unclear. METHODS Patients CSVD from a hospital‐based cohort ( n = 194) individuals presumed early community‐based 319) were included. Oculo‐gait measured using the artificial intelligence (AI) –assisted ‘EyeKnow’ eye‐tracking ‘ReadyGo’ motor evaluation systems. Multivariable linear logistic...
Major depressive disorder (MDD) is a common psychiatric disorder. With systematic antidepressant treatment, 50–75% of patients have treatment response but require 4–6 weeks to their symptoms alleviated. Therefore, researchers anticipate the development novel fast-acting antidepressants. Previous studies revealed that decrease bio-energetic metabolism may contribute occurrence depression, while our team has found adenosine triphosphate (ATP) and phosphocreatine (PCr) be antidepressants in...
Abstract Background The respiratory microbiota plays a crucial role in the development of tuberculosis (TB). While existing research has underscored imbalances adult patients with TB, information regarding lower tract (LRT) pediatric TB remains scarce. Methods We employed 16S rRNA gene sequencing technology to investigate LRT microbial communities 85 children different ages active severities, 33 infectious diseases other than and 48 sex‐ age‐matched healthy children. Results A marked...
Aim of the study: Acute central nervous system viral infections are progressive and inflammatory diseases with cells infiltrating into (CNS), thyroid hormone (TH) level is associated oxidative antioxidant status. Variations in stress status related to pathogenesis diseases. Our study aimed investigate possible correlation between CNS TH levels stimulating (TSH), free thyroxine (fT4) triiodothyronine (fT3).Materials methods: We measured serum concentrations TSH, fT4, fT3 206 individuals,...
Objective To observe the changes of plasma endothelin-1 (ET-1) and calcitonin gene related peptide (CGRP) calciurn dobesilate in treatment diabetic retinopathy (DR). Methods This is a self-control trial. Plasma ET-1 CGRP concentrations were measured with RIA 100 patients DR received calcium (pretherapy, post-treatment: 2w, 1m, 3m 6m). Results The content 186.15±43.89, 153.82±39.54, 121.27±38.45, 72.61±30.24 71.89±24.37ng/L at pretherapy post-treatment (2w, 3m, 6m), respectively; that...
Background and Objective To evaluate the impact of blood clearance mechanisms on neurologic damage functional outcomes after intracerebral hemorrhage (ICH) in rats. Methods A rat model ICH was established through pre-cannulation injection autologous arterial into caudate nucleus. Blood supplemented with 6-amino-caproic acid (a procoagulant), low-molecular-weight heparin (an anticoagulant), or vehicle. Relationships between hematoma volume edema size were assessed at different times. Results...