A5086497343- Sinusitis and nasal conditions
- Respiratory Support and Mechanisms
- Asthma and respiratory diseases
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Nerve injury and regeneration
Qilu Hospital of Shandong University
2024-2025
Institute of Genetics and Developmental Biology
2023
Chinese Academy of Sciences
2023
University of Chinese Academy of Sciences
2023
Noncovalent interactions between cells and environmental cues have been recognized as fundamental physiological that regulate cell behavior. However, the effects of covalent biomaterials on behavior not examined. Here, we demonstrate a combined strategy based conjugation (collagen fibers/lipid nanoparticles) various (exogenous neural progenitor cells/astrocytes/endogenous tissue-resident cells) to promote regeneration after spinal cord injury (SCI). We found metabolic azido-labeled human...
Neutrophilic inflammation contributes to multiple chronic inflammatory airway diseases, including asthma and rhinosinusitis with nasal polyps (CRSwNP), is associated an unfavorable prognosis. Here, using single-cell RNA sequencing (scRNA-seq) profile human mucosa obtained from the inferior turbinates, middle of CRSwNP patients, we identify two IL-1 signaling-induced cell subsets—LY6D+ club cells IDO1+ fibroblasts—that promote neutrophil recruitment by respectively releasing S100A8/A9...
Abstract Neutrophilic inflammation contributes to multiple chronic inflammatory airway diseases, including asthma and rhinosinusitis with nasal polyps (CRSwNP), is associated an unfavorable prognosis. Here, using single-cell RNA sequencing (scRNA-seq) profile human mucosa obtained from the inferior turbinates, middle of CRSwNP patients, we identified two IL-1 signaling-induced cell subsets— LY6D + club cells IDO1 fibroblasts—that promote neutrophil recruitment by respectively releasing...