A5069869364- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Terahertz technology and applications
- Circular RNAs in diseases
- Advanced Chemical Sensor Technologies
- Extracellular vesicles in disease
- Metamaterials and Metasurfaces Applications
- Plasmonic and Surface Plasmon Research
- Spectroscopy and Quantum Chemical Studies
- Spectroscopy and Chemometric Analyses
- RNA modifications and cancer
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Molecular Spectroscopy and Structure
- Spectroscopy and Laser Applications
- RNA Research and Splicing
- Fermentation and Sensory Analysis
- Ginseng Biological Effects and Applications
- Maritime Navigation and Safety
- Advanced Computational Techniques and Applications
- Plant and animal studies
- Millimeter-Wave Propagation and Modeling
- Cardiovascular Health and Risk Factors
- Optical and Acousto-Optic Technologies
- Wave and Wind Energy Systems
- Inflammatory Biomarkers in Disease Prognosis
Guilin University of Electronic Technology
2012-2025
Northern Jiangsu People's Hospital
2019-2024
Soochow University
2021-2024
First Affiliated Hospital of Soochow University
2024
Jiangsu Province Hospital
2016-2020
Nanjing Medical University
2016-2020
Yangzhou University
2020
Xidian University
2014-2018
Nantong University
2012
Guilin University
2012
Circulating miRNAs in serum may serve as promising diagnostic biomarkers for patients with gastric cancer.Using qRT-PCR-based Exiqon panel, we identified 58 differentially expressed from three cancer pool samples and one normal control (NC) the initial screening phase. Identified were further validated training (49 vs. 47 NCs) validation phases (154 120 using qRT-PCR. The expression levels of also determined tissues, arterial serum, exosomes.Consequently, six (miR10b-5p, miR132-3p,...
Dysregulated expression of specific microRNAs (miRNAs) in serum has been recognised as promising diagnostic biomarkers for colorectal cancer (CRC). In the initial screening phase, a total 32 differentially expressed miRNAs were selected by quantitative reverse transcription polymerase chain reaction (qRT-PCR) based Exiqon panel with 3 CRC pool samples and 1 normal control (NC) pool. Using qRT-PCR, further confirmed training (30 VS. 30 NCs) testing stages (136 90 NCs). We identified that...
As a special microbial fermented tea, the aging year of Liubao tea is crucial determinant its value. This study established fast and high-precision method for identifying age by combining terahertz time-domain spectroscopy technology with chemometric methods. Most common optimization algorithms rely too much on guidance elite individuals in process are prone to fall into local optimal solutions. Therefore, this paper uses differentiated creative search algorithm global thinking optimize...
Abstract Circulating microRNAs (miRNAs) have been used as promising diagnostic biomarkers for esophageal squamous cell carcinoma (ESCC). We performed miRNA expression profiling using quantitative reverse transcription polymerase chain reaction (qRT‐PCR) based Exiqon panels from three ESCC pools and one normal control (NC) pool samples. Using qRT‐PCR, identified serum miRNAs were further confirmed in training (32 vs. 32 NCs) testing stages (108 96 NCs). Consequently, five (miR‐20b‐5p,...
// Xin Zhou 1, * , Wei Wen 2, Jun Zhu 3, Zebo Huang 1 Lan Zhang Huo Lian-Wen Qi 4 Xia Shan 5 Tongshan Wang Wenfang Cheng 6 Danxia 7 Yin 8 Yan Chen 9 Yongqian Shu 10 Ping Liu Department of Oncology, First Affiliated Hospital Nanjing Medical University, 210029, PR China 2 Thoracic Surgery, 3 Radiation Jiangsu Cancer Hospital, 210009, State Key Laboratory Natural Medicines and Pharmacognosy, Pharmaceutical Respiration, The Jiangning 210000, Gastroenterology, Third Soochow Changzhou 213003,...
The rapid and sensitive detection of pesticide residue is essential for ensuring the food safety consumers. However, there are many disadvantages current approaches to detect residue, such as complex pre-treatment low sensitivity. In this paper, we demonstrate a highly carbendazim method by using terahertz time-domain spectroscopy (THz-TDS) combined with metamaterial. metamaterial composed metal ohm ring arrays, applied in detecting different concentrations carbendazim. Resonant peaks move...
Some reports have evaluated the prognostic relevance of microRNAs (miRNAs) in patients with pancreatic cancer (PC). However, most studies focused on limited miRNAs small number patients. The aim study is to identify a panel miRNA signature that could predict prognosis PC data from Cancer Genome Atlas (TCGA). A total 167 corresponding clinical were enrolled our study. significantly associated overall survival (OS) identified Cox proportional regression model. risk score formula was developed...
Abstract Dysregulated micro RNA s (mi s) in the plasma of patients with lung squamous cell carcinoma ( LSCC ) might serve as biomarkers for diagnosis. The expression mi was performed using quantitative reverse transcription–polymerase chain reaction qRT ‐ PCR on basis Exiqon panels initial screening phase including three male pool samples and one normal control NC sample (per 10 were pooled sample). After training (32 vs. 31 s), testing (55 55 external validation (15 15 stages via , a...
BACKGROUND: Circulating microRNAs (miRNAs) have been implicated as novel biomarkers for various types of cancers. The aim the study is to identify serum miRNAs with potential in detecting gastric cardia adenocarcinoma (GCA). METHODS: A three-phase was designed 102 GCA patients and 84 cancer-free controls. In screening phase (3 pools vs. 1 normal control (NC) pool), a total 35 were identified using quantitative reverse transcription polymerase chain reaction (qRT-PCR) based Exiqon panel....
BACKGROUND: Recently, many studies have investigated the value of hematologic markers in prognosis gastric cancer (GC). However, most only focused on pre-operative markers. The aim this study was to investigate prognostic resectable GC patients at three different periods treatment (preoperative, postoperative and before first chemotherapy). METHODS: Clinical data from 451 were retrospectively collected. Hematologic including leukocyte, neutrophil, lymphocyte, red blood cell (RBC), platelet,...
Abstract Background Circulating microRNAs (miRNAs) have become reliable sources of non‐invasive biomarkers for cancer diagnosis. Identification promising miRNA in plasma might benefit a lot to the detection nasopharyngeal carcinoma (NPC). Methods The Exiqon qPCR panel was used screening stage identify candidate miRNAs, which were further verified by quantitative reverse transcription polymerase chain reaction (qRT‐PCR) following three stages among samples from 200 NPC patients and 189...
// Lan Zhang 1, * , Xia Shan 2, Jun Wang 3, Zhu 4 Zebo Huang 1 Huo Xin Zhou Wenfang Cheng 5 Yongqian Shu Wei and Ping Liu Department of Oncology, First Affiliated Hospital Nanjing Medical University, 210029, PR China 2 Respiration, The Jiangning 210000, 3 Thoracic Surgery, Radiation Jiangsu Cancer Hospital, 210009, Gastroenterology, These authors have contributed equally to this work Correspondence to: Zhu, email: zhuwei@njmu.edu.cn Liu, liupinga28@163.com Keywords: serum microRNA, lung SCC,...
The metastasis of gastric cancer, one the most common tumors, has a molecular mechanism that is still largely unclear. Here we investigated role possible tumor-suppressor miR-1296-5p in cell migration and invasion ERBB2-positive cancer. It found was significantly down-regulated cancer tissues. Moreover, it lymph node metastatic tissues compared with non-metastatic luciferase activity ERBB2 3'-untranslated region-based reporters constructed SNU-216 NUGC-4 cells suggested target gene...