- Health Systems, Economic Evaluations, Quality of Life
- Diabetes Treatment and Management
- Sepsis Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Pelvic floor disorders treatments
- Sodium Intake and Health
- Diverticular Disease and Complications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Anorectal Disease Treatments and Outcomes
- Heart Failure Treatment and Management
- Pancreatic function and diabetes
- Medication Adherence and Compliance
- Nutritional Studies and Diet
- Long-Term Effects of COVID-19
- Bone health and osteoporosis research
- COVID-19 and healthcare impacts
- Meta-analysis and systematic reviews
- Cardiac, Anesthesia and Surgical Outcomes
- Healthcare Policy and Management
- Malaria Research and Control
- Older Adults Driving Studies
- Statistical Methods in Clinical Trials
- COVID-19 Clinical Research Studies
- Renal function and acid-base balance
- Diabetes Management and Research
University of Applied Sciences and Arts of Southern Switzerland
2022-2025
The George Institute for Global Health
2019-2025
UNSW Sydney
2019-2025
University of Bern
2024
Austin Health
2024
George Institute for Global Health
2023-2024
George Institute for Global Health
2021-2023
University College London
2023
Sapienza University of Rome
2008-2022
The University of Sydney
2022
Salt substitutes with reduced sodium levels and increased potassium have been shown to lower blood pressure, but their effects on cardiovascular safety outcomes are uncertain.
Abstract Italy has been the first-hit European country to face outbreak of coronavirus disease 2019 (COVID-19). Aim this survey was assess in depth impact on healthcare workers (HCW). A 40-item online disseminated via social media inviting Italian HCW, with questions exploring demographics, health status and work environment respondents. total 527 were invited take part March 2020, whom 74% (n = 388) responded survey. Of these, 235 (61%) women. HCW mostly physicians (74%), from...
Canagliflozin reduced renal and cardiovascular events in people with type 2 diabetes the CREDENCE trial. We assessed efficacy safety of canagliflozin by initial estimated glomerular filtration rate (eGFR).CREDENCE randomly assigned 4401 participants an eGFR 30 to <90 ml/min per 1.73 m2 substantial albuminuria 100 mg or placebo. used Cox proportional hazards regression analyze effects on outcomes within screening subgroups (30 <45, 45 <60, 60 m2) linear mixed models slope.At screening, 1313...
Little is understood of Ebola virus disease (EVD) transmission dynamics and community compliance with control measures over time. Understanding these interactions essential if interventions are to be effective in future outbreaks. We conducted a mixed-methods study explore factors rural village that experienced sustained EVD Kailahun District, Sierra Leone.We reconstructed using cross-sectional survey April 2015, cross-referenced our results surveillance, burial, Management Centre (EMC)...
BackgroundChildhood visual impairment is a major public health concern that requires effective screening and early intervention. We investigated the effectiveness of Peek school eye health, smartphone-based sight test referral system (comprising Acuity test, simulation cards, short message service [SMS] reminders), versus standard care (Snellen's Tumbling-E card written referral).MethodsWe initially compared performance both Snellen to backlit EDTRS LogMAR acuity chart. did cluster...
As indicators of burden malaria have substantially decreased in The Gambia, reaching a pre-elimination status may be attainable. Achieving this goal requires in-depth understanding the current Plasmodium falciparum infection. A nationwide cross-sectional survey was conducted 2012 to determine prevalence P. infection, and describe its heterogeneity associated risk factors. Finger-prick blood samples were collected for microscopy, species-specific PCR haemoglobin measurement. total 9,094...
Abstract BACKGROUND The effect of chronic use renin–angiotensin–aldosterone system (RAAS) inhibitors on the severity COVID-19 infection is still unclear in patients with hypertension. We aimed to investigate association between angiotensin-converting enzyme (ACEIs) or angiotensin II receptor blockers (ARBs) and COVID-19-related outcomes hypertensive patients. METHODS A single-center study was conducted 133 consecutive subjects presenting emergency department acute respiratory symptoms and/or...
Background: People with type 2 diabetes and chronic kidney disease experience a high burden of hypertension, but the magnitude consistency blood pressure (BP) lowering canagliflozin in this population are uncertain. Whether effects on cardiovascular outcomes vary by baseline BP or BP-lowering therapy is also unknown. Methods: The CREDENCE trial (Canagliflozin Renal Events Diabetes Established Nephropathy Clinical Evaluation) randomized people to placebo. In post hoc analysis, we investigated...