- Prenatal Screening and Diagnostics
- Anesthesia and Pain Management
- Nausea and vomiting management
- Congenital Heart Disease Studies
- Parvovirus B19 Infection Studies
- Intraocular Surgery and Lenses
- Down syndrome and intellectual disability research
- Fetal and Pediatric Neurological Disorders
Amsterdam University Medical Centers
2021-2022
University of Amsterdam
2022
Vrije Universiteit Amsterdam
2021
Amsterdam UMC Location Vrije Universiteit Amsterdam
2019
Emma Kinderziekenhuis
2019
The introduction of the non-invasive prenatal test (NIPT) has shifted screening landscape. Countries are exploring ways to integrate NIPT in their national programs, either as a first- or second-tier test. This study aimed describe how uptake fetal aneuploidy changed after and first-tier within program Netherlands.A population-based register Netherlands, recording screening. Data from all pregnant women choosing have first-trimester combined (FCT) between January 2007 March 2019 were...
To evaluate if non-invasive prenatal testing (NIPT) affects livebirth (LB) prevalence of Down syndrome (DS) in the Netherlands.Data from clinical genetics laboratories and Working Party on Prenatal Diagnosis Therapy (2014-2018) previous published data (1991-2013) were used to assess trends for DS LB reduction percentage (the net decrease LBs resulting selective termination pregnancies). Statistics Netherlands provided general population data.DS increased 11.6/10,000 1991 15.9/10,000 2002...
Local anesthesia with mepivacaine is used for vaginal deliveries and minor surgeries of the vagina perineum as repair an episiotomy or perineal laceration. Neonatal intoxication caused by local maternal has been rarely reported. We present a case term female infant unexplained cardiorespiratory distress several neurologic findings, including seizures, one hour after birth. Electrocardiogram showed second-degree atrioventricular block left-bundle branch block. Blood measures in patient...
Abstract The total uptake of prenatal aneuploidy screening for Down syndrome (DS) is increasing worldwide. As a result diagnosis DS and subsequent termination pregnancy, livebirth prevalence decreasing. aim this study to explore the impact an on neonatal mortality morbidity in DS. This retrospective cohort 253 neonates with born between 2012 2018 that were seen at outpatient clinic five hospitals Netherlands. medical files reviewed maternal characteristics morbidities. Dutch national birth...