A5063036296- Viral-associated cancers and disorders
- SARS-CoV-2 and COVID-19 Research
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Cytomegalovirus and herpesvirus research
- Cervical Cancer and HPV Research
- MicroRNA in disease regulation
- Sex work and related issues
- COVID-19 Clinical Research Studies
- HIV Research and Treatment
- Lymphoma Diagnosis and Treatment
- HIV/AIDS Research and Interventions
- Cholangiocarcinoma and Gallbladder Cancer Studies
- SARS-CoV-2 detection and testing
- Viral Infections and Immunology Research
- HIV/AIDS drug development and treatment
- Cancer-related molecular mechanisms research
- Hepatitis Viruses Studies and Epidemiology
- Animal Virus Infections Studies
- Parvovirus B19 Infection Studies
- Extracellular vesicles in disease
- Respiratory viral infections research
- Viral Infections and Vectors
Iran University of Medical Sciences
2007-2025
Kansas Department for Children and Families
2021
Tehran University of Medical Sciences
2015-2019
Kermanshah University of Medical Sciences
2019
Babol Noshirvani University of Technology
2019
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for development novel, safe more efficient antiviral agents. In this study, we evaluated activity zinc oxide nanoparticles (ZnO-NPs) PEGylated against H1N1 influenza virus.The were characterized using inductively coupled plasma mass spectrometry, x-ray diffraction analysis, electron microscopy. MTT assay was applied...
Due to its global burden, Targeting Hepatitis B virus (HBV) infection in humans is crucial. Herbal medicine has long been significant, with flavonoids demonstrating promising results. Hence, the present study aimed establish a way of identifying anti-HBV activities. Flavonoid structures activities were retrieved. A flavonol-based pharmacophore model was established using LigandScout v4.4. Screening performed PharmIt server. QSAR equation developed and validated independent sets compounds....
We aimed to determine the possible inhibitory effects of zinc oxide nanoparticles (ZnO-NPs) and polyethylene glycol (PEG)-coated ZnO-NPs (ZnO-PEG-NPs) on herpes simplex virus type 1 (HSV-1).PEGylated were synthesized by mechanical method. Antiviral activity was assessed 50% tissue culture infectious dose (TCID50) real-time PCR assays. To confirm antiviral expression HSV-1 antigens, indirect immunofluorescence assay also conducted.200 μg/ml ZnO-PEG-NPs could result in 2.5 log10 TCID50...
One of the hallmarks COVID-19 is overwhelming inflammation, which plays a very important role in pathogenesis COVID-19. Thus, identification inflammatory factors that interact with SARS-CoV-2 can be to control and diagnose severity The aim this study was investigate expression patterns inflammation-related non-coding RNAs (ncRNAs) including MALAT-1, NEAT-1, THRIL, miR-155-5p from acute phase recovery COVID-19.Total RNA extracted Peripheral Blood Mononuclear Cell (PBMC) samples 20 patients...
MicroRNAs, or miRNAs, with regulatory performance in inflammatory responses and infection are the prevalent manifestations of severe coronavirus disease (COVID-19). This study aimed to evaluate whether PBMC miRNAs diagnostic biomarkers screen ICU COVID-19 diabetic subjects.
In this pandemic SARS-CoV-2 crisis, any attempt to contain and eliminate the virus will also stop its spread consequently decrease risk of severe illness death. While ozone treatment has been suggested as an effective disinfection process, no precise mechanism action previously reported. This study aimed further investigate effect on SARS-CoV-2. Therefore, collected from nasopharyngeal oropharyngeal swab sputum samples symptomatic patients was exposed for different exposure times. The...
Background This study aimed to investigate the prevalence of recently emerged members Redondoviridae family (ReDoVs) in individuals with periodontitis. Methods involved real-world data from 230 participants, 115 chronic periodontitis and an independent population consisting participants oral hygiene habits selected refferals, approved by experts October 2023 May 2024. Demographic, health-related, behavioral were collected. Gingival samples analyzed for ReDoVs using polymerase chain reaction...
Redondoviridae is a newly discovered virus family linked to oral and respiratory conditions in people, while there still debate about whether it also coinfected with other viruses. This study aimed determine the frequency of Redondovirus (ReDoV) nasopharyngeal samples investigate any possible links SARS-CoV-2 infections.
Cervical cancer is the leading cause of death from in under-developed countries. Human papilloma virus (HPV) 16 and 18 are most prevalent types associated with carcinogenesis cervix. Conventional Polymerase Chain Reaction (PCR), type-specific consensus primer-based PCR followed by sequencing, Restriction Fragment Length Polymorphism (RFLP) or hybridization specific probes common methods for HPV detection typing. In addition, some researchers have developed a multiplex simultaneous typing...
Complete SARS-CoV-2 genome sequencing in the early phase of outbreak Iran showed two independent viral entries. Subsequently, as part a surveillance project, we aimed to characterize genetic diversity over one year after emerging.We provided 319 whole-genome sequences used monitor circulating lineages March 2020-May 2021 time interval.The temporal dynamics major clades/lineages is comparable global perspective and represent 19A clade (B.4) dominating first disease wave, followed by 20A...
Background: Epstein-Barr virus (EBV) is associated with different malignant diseases, such as Hodgkin lymphoma (HL) and lymphoproliferative disorders. Patients hematologic malignancies by variable severity could be suspected for the infection types of this virus. This preliminary study reported genotyping related viral load in Iranian patients estimation possible factors affecting malignancy. Methods: Peripheral blood mononuclear cells (PBMC) HL (n=20), NHL (n=29), acute lymphocytic leukemia...
The outbreak of SARS-CoV-2 (COVID-19) has attracted much attention to study its possible presence and airborne transmission. possibility COVID-19 transmission in indoor environments is debatable. present examined the concentration viral RNA-containing particles produced directly or indirectly by breathing coughing confirmed patients carriers without symptoms. Some studies do not accept this method (COVID-19 transmission). aimed measure exposure health care personnel that may have been...