A5016342068- Hepatitis B Virus Studies
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Cytomegalovirus and herpesvirus research
- Virus-based gene therapy research
- SARS-CoV-2 and COVID-19 Research
- Cervical Cancer and HPV Research
- Herpesvirus Infections and Treatments
- Viral gastroenteritis research and epidemiology
- Influenza Virus Research Studies
- MicroRNA in disease regulation
- Esophageal Cancer Research and Treatment
- Animal Virus Infections Studies
- RNA Interference and Gene Delivery
- Respiratory viral infections research
- Parvovirus B19 Infection Studies
- HIV Research and Treatment
- Virology and Viral Diseases
- Viral Infections and Vectors
- COVID-19 Clinical Research Studies
- Viral Infections and Immunology Research
- Opioid Use Disorder Treatment
- Vaccine Coverage and Hesitancy
- Esophageal and GI Pathology
Golestan University
2015-2024
Golestan University of Medical Sciences
2015-2024
The University of Queensland
2023
Zabol University of Medical Sciences
2023
Tehran University of Medical Sciences
2013-2021
Jahrom University of Medical Sciences
2019
Alborz University of Medical Sciences
2019
Bushehr University of Medical Sciences
2018
Forschungs- und Beratungsstelle Arbeitswelt
2018
Infectious Disease Research Institute
2017
Currently available anti-influenza drugs are often associated with limitations such as toxicity and the appearance of drug-resistant strains. Therefore, there is a pressing need for development novel, safe more efficient antiviral agents. In this study, we evaluated activity zinc oxide nanoparticles (ZnO-NPs) PEGylated against H1N1 influenza virus.The were characterized using inductively coupled plasma mass spectrometry, x-ray diffraction analysis, electron microscopy. MTT assay was applied...
Cervical cancer is the second-most-common cause of malignancies in women worldwide, and oncogenic activity human papilloma virus types (HPV) E7 protein has a crucial role anogenital tumors. In this study, we have designed therapeutic vaccine based on chitosan nanodelivery systems to deliver HPV-16 DNA vaccine, considered as tumor specific antigen for immunotherapy HPV-associated cervical cancer. We developed Nano-chitosan (NCS) carrier system intramuscular administration using recombinant...
Background: The International Agency for Research on Cancer (IARC) recently classified opium use as a Group 1 carcinogen. However, much remains to be studied the relation between and cancer. We designed Iranian Opium (IROPICAN) study further investigate association of cancers head neck, bladder, lung, colon rectum. In this paper, we describe rationale, design, some initial results IROPICAN Study. Methods: is multi-center case-control conducted in 10 provinces Iran. cases were all...
The effects of garlic (Allium sativum) and thyme (Thymus vulgaris) extracts a probiotic on growth performance, intestinal tissue morphology, microbial flora in broilers were investigated. A total 240 Ross 308 male divided into 4 treatments, with replicates 15 birds. Treatments 2 plant (1,000 ppm) the ppm from 0 to 7 d, 500 8 21 250 22 42 d) added drinking water, control group no additives. Birds different treatments received same diets during experimental period. Feed intake, BW gain, FCR...
Background Several case-control studies have shown associations between the risk of different cancers and self-reported opium use. Inquiring into relatively sensitive issues, such as history drug use, is usually prone to information bias. However, in order justify findings these types studies, we quantify level a negative In current study, aimed evaluate sensitivity opioid use suggest suitable control groups for on cancer. Methods compare validity cross-validated response two subjects 1) 178...
Abstract Scant evidence exists to support the association of opium use with head and neck cancer, limited larynx oral cavity. In a multicenter case‐control study—Iran Opium Cancer study, we recruited 633 cases squamous cell carcinoma (HNSCC) (254 lip cavity, 54 pharynx, 327 28 other subsites within neck) 3065 frequency‐matched controls from April 2016 2019. Odds ratios (ORs) for 95% confidence intervals (95% CIs) were obtained using mixed‐effects logistic regression because heterogeneity...
Purpose: Paclitaxel is a generic drug produced based on Taxol which an extract of Taxus tree, well known for its anticancer and antibacterial effects. This study was aimed at building up agent with the benefits both silver ions Taxol, together less cytotoxic Materials Methods: Colloidal nanoparticles (AgNPs) were synthesized by reducing aqueous AgNO 3 leaf nonphotomediated conditions, without any catalyst, template or surfactant. The AgNP production confirmed ultraviolet-visible (UV-VIS)...
Hepatitis B virus (HBV) infection is one of the most prevalent public health problems worldwide (especially in developing countries).This study was carried out to determine seroprevalence HBV and its co-infection with hepatitis D (HDV) C (HCV) viruses northeastern part Iran.A population-based cross-sectional Iran.As many as 1,850 subjects were explored for HBsAg. Anti-HDV anti-HCV antibodies assessed HBsAg-positive cases.Proportions compared by Chi-square Fisher's exact tests.The mean age...
Abstract Background Bladder cancer (BC) is the 10th most common type of worldwide and fourth in Iran. Opium use considered as one risk factors for BC. We aim to assess association between various parameters opium use, which Iran mainly ingested or smoked forms, Method In this multi-centre case-referent study Iran, 717 BC cases 3477 referents were recruited from May 2017 until July 2020. Detailed histories (duration, amount, frequency) potential confounders collected by trained interviewers....
Despite increasing awareness of walkable neighborhoods’ health benefits, the relationship between walkability and mental remains unclear. This study examined depression in West Virginia which has highest rate according to 2023 CDC report. Increasing neighborhood was hypothesized result a reduction encounters. Using most recent census tract boundaries (N = 546), National Walkability Index (NWI) scores were aggregated from 2019 block group data tract-level averages. Depression prevalence...
Background and Objectives: Viral membrane glycoproteins are essential for host cell recognition, fusion immune evasion, making them critical targets antiviral therapies vaccine development. However, their isolation in na- tive conformation is challenging due to structural complexity limitations of conventional purification methods. The aim current study was develop a cost-effective, reproducible method the glycoprotein B (gB) from Herpes Simplex Virus type 1 (HSV-1) while maintaining its...
Chitosan nanoparticles (CS NPs) were prepared as a carrier for Human papillomavirus type 16 HPV-16) E7 gene and their transfection ability evaluated in vitro. The plasmid expressing green fluorescent protein (pEGFP) was used reporter gene. Gel electrophoresis demonstrated full binding of CS NPs with the pDNA. CS-pEGFP efficient CHO cells expression proteins well observed. confirmed under SDS-PAGE western blot analysis. As conclusion may serve an effective nonviral delivery nucleotides into...
Immunomodulators and Nucleotide analogues have been used globally for the dealing of chronic hepatitis B virus (HBV) infection. However, development drug resistance is a major limitation to their long-term effectiveness.The aim this study was characterize reverse transcriptase (RT) protein variations among Iranian HBV carriers who did not receive any antiviral treatments.Hepatitis partial RT genes from 325 in active carrier patients were amplified directly sequenced. Nucleotide/amino acid...