- Respiratory Support and Mechanisms
- Intensive Care Unit Cognitive Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiac Arrest and Resuscitation
- Venomous Animal Envenomation and Studies
- Sepsis Diagnosis and Treatment
- Nosocomial Infections in ICU
- Ion channel regulation and function
- Airway Management and Intubation Techniques
- Cardiac electrophysiology and arrhythmias
- Asthma and respiratory diseases
- Family and Patient Care in Intensive Care Units
- Inhalation and Respiratory Drug Delivery
- Pneumonia and Respiratory Infections
- Hemodynamic Monitoring and Therapy
- Emergency and Acute Care Studies
- Pulmonary Hypertension Research and Treatments
- Palliative Care and End-of-Life Issues
- Neonatal Respiratory Health Research
- Heart Failure Treatment and Management
- Acute Kidney Injury Research
- Healthcare Decision-Making and Restraints
- Poisoning and overdose treatments
- Mechanical Circulatory Support Devices
- Study of Mite Species
Hospital Fatuma Bourguiba Monastir
2015-2025
University of Monastir
2011-2022
University of Genoa
2021
Weatherford College
2021
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2010-2017
Intensive Care Society
2000-2015
Tunica Museum
2011
Inserm
2010
Université Paris-Est Créteil
2010
Hôpital Albert-Chenevier
2010
Baseline characteristics and management have changed over time in patients requiring mechanical ventilation; however, the impact of these changes on patient outcomes is unclear.To estimate whether mortality mechanically ventilated has time.Prospective cohort studies conducted 1998, 2004, 2010, including receiving ventilation for more than 12 hours a 1-month period, from 927 units 40 countries. To examine effects intensive care units, we performed generalized estimating equation models.We...
ContextContinuous positive airway pressure (CPAP) is widely used in the belief that it may reduce need for intubation and mechanical ventilation patients with acute hypoxemic respiratory insufficiency.ObjectiveTo compare physiologic effects clinical efficacy of CPAP vs standard oxygen therapy hypoxemic, nonhypercapnic insufficiency.Design, Setting, PatientsRandomized, concealed, unblinded trial 123 consecutive adult who were admitted to 6 intensive care units between September 1997 January...
Many sources of conflict exist in intensive care units (ICUs). Few studies recorded the prevalence, characteristics, and risk factors for conflicts ICUs.To record ICUs.One-day cross-sectional survey ICU clinicians. Data on perceived week before day were obtained from 7,498 staff members (323 ICUs 24 countries).Conflicts by 5,268 (71.6%) respondents. Nurse-physician most common (32.6%), followed among nurses (27.3%) staff-relative (26.6%). The conflict-causing behaviors personal animosity,...
Intensive care unit (ICU) patients undergo several diagnostic and therapeutic procedures every day. The prevalence, intensity, risk factors of pain related to these are not well known.To assess self-reported procedural intensity versus baseline pain, examine differences across procedures, identify for intensity.Prospective, cross-sectional, multicenter, multinational study associated with 12 procedures. Data were obtained from 3,851 who underwent 4,812 in 192 ICUs 28 countries.Pain on a 0-10...
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Objective: To describe and compare characteristics, ventilatory practices, associated outcomes among mechanically ventilated patients with different types of brain injury between neurologic nonneurologic patients. Design: Secondary analysis a prospective, observational, multicenter study on mechanical ventilation. Setting: Three hundred forty-nine intensive care units from 23 countries. Patients: We included 552 (362 stroke 190 trauma). For comparison we used control group 4,030 mixed who...
<h3>Background</h3> There are limited data on the impact of body mass index outcomes in mechanically ventilated patients. <h3>Methods</h3> Secondary analysis a cohort including 4698 patients ventilated. Patients were screened daily for management mechanical ventilation, complications (acute respiratory distress syndrome, sepsis, ventilator associated pneumonia, barotrauma), organ failure (cardiovascular, respiratory, renal, hepatic, haematological) and mortality intensive care unit. To...
The use of noninvasive ventilation (NIV) as an early weaning/extubation technique from mechanical remains controversial.To investigate NIV effectiveness in difficult-to-wean patients with chronic hypercapnic respiratory failure (CHRF).In 13 intensive care units, 208 CHRF intubated for acute (ARF) who failed a first spontaneous breathing trial were randomly assigned to three groups: conventional invasive weaning group (n = 69), extubation followed by standard oxygen therapy 70), or 69). was...
This statement outlines a review of the literature and current practice concerning prevalence, clinical significance, diagnosis management dyspnoea in critically ill, mechanically ventilated adult patients. It covers definition, pathophysiology, epidemiology, short- middle-term impact, detection quantification, prevention treatment dyspnoea. represents collaboration European Respiratory Society Intensive Care Medicine. Dyspnoea ranks among most distressing experiences that human beings can...
Objective: To determine the usual practice for setting tidal volume and other ventilatory parameters in patients with acute respiratory distress syndrome (ARDS) late 1990s to independent effects of these practices on intensive care unit mortality. Design: Subanalysis a prospective observational study. Multivariable logistic regression was used analyze management Setting: A total 361 units 20 countries March 1998. Patients: 467 mechanically ventilated ARDS. Interventions: None. Measurements...
To investigate the effect of norepinephrine on static (right atrial pressure, pulmonary artery occlusion pressure ) and dynamic (pulse variation arterial systolic variation) preload indicators in experimental hemorrhagic shock.Prospective controlled study.Animal research laboratory.Six anesthetized mechanically ventilated dogs.Dogs were instrumented for measurement blood catheter derived variables including right cardiac output. Simultaneously, pulse calculated. Pulse is difference between...
Cardiac biomarkers are used to distinguish acute dyspnea due left-heart dysfunction from that of pulmonary origin. However, they have not been assessed in the specific setting exacerbation chronic obstructive disease (AECOPD), where might be released without impairment.To assess accuracy troponin T and amino-terminal pro-brain natriuretic peptide (NT-proBNP) diagnosis AECOPD associated with left ventricular (LV) dysfunction.Both were measured 148 consecutive patients on intensive care unit...