A5024002185- Gastric Cancer Management and Outcomes
- Colorectal and Anal Carcinomas
- Colorectal Cancer Surgical Treatments
- COVID-19 Clinical Research Studies
- Gastrointestinal Tumor Research and Treatment
- Lung Cancer Research Studies
- Bone Tumor Diagnosis and Treatments
- Colorectal Cancer Screening and Detection
- Genetic factors in colorectal cancer
- Hepatocellular Carcinoma Treatment and Prognosis
- Neuroendocrine Tumor Research Advances
- Salivary Gland Tumors Diagnosis and Treatment
- Oral and Maxillofacial Pathology
- Nonmelanoma Skin Cancer Studies
- Metastasis and carcinoma case studies
- Liver Disease Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Cancer and Skin Lesions
- COVID-19 diagnosis using AI
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal and related cancers
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- COVID-19 and Mental Health
- Head and Neck Anomalies
- Occupational and environmental lung diseases
Virginia Tech
2024
Yonsei University
2004-2024
Severance Hospital
2020-2024
National Health Insurance Service
2007-2021
National Health Insurance Service Ilsan Hospital
2010-2021
Seoul St. Mary's Hospital
2013
Catholic University of Korea
2013
Gyeongsang National University
2013
University of Chicago
2013
Ewha Womans University
2009
The rapid spread of COVID-19 has resulted in the shortage medical resources, which necessitates accurate prognosis prediction to triage patients effectively. This study used nationwide cohort South Korea develop a machine learning model predict based on sociodemographic and information. Of 10,237 patients, 228 (2.2%) died, 7772 (75.9%) recovered, 2237 (21.9%) were still isolation or being treated at last follow-up (April 16, 2020). Cox proportional hazards regression analysis revealed that...
Purpose The role of tumor-infiltrating lymphocytes (TILs) in predicting lymph node metastasis (LNM) patients with T1 colorectal cancer (CRC) remains unclear. Furthermore, clinical utility a machine learning–based approach has not been widely studied.Materials and Methods Immunohistochemistry for TILs against CD3, CD8, forkhead box P3 both center invasive margin the tumor were performed using surgically resected CRC slides. Three hundred sixteen enrolled categorized into training (n=221)...
Abstract Background Increased body mass index (BMI) has been associated with a higher risk of severe coronavirus disease 2019 (COVID-19) infections. However, whether obesity is factor for contracting COVID-19 hardly investigated so far. Methods We examined the association between BMI level and infection in nationwide case-control study comprised 3788 case patients confirmed to have 24 January 9 April 2020 15 152 controls matched by age sex, who were aged 20 years or more underwent National...
It is unclear whether smokers are more vulnerable to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. This study aimed evaluate the association between smoking and risk of SARS-CoV-2 A matched case-control was conducted using a large nationwide database. The case group included patients with infection confirmed by Korea Centers for Disease Control Prevention, control randomly sampled from general Korean population in National Health Insurance Service database matching...
Purpose: The aim of this study was to analysis the clinicopathological characteristics and prognosis colorectal cancer (CRC) under age 50 years.Methods: Between January 2009 December 2018, 1,126 primary CRC patients were included from National Health Insurance Service Ilsan Hospital. divided into group 1 (n=111, ≤50 years) 2 (n=1,015, >50 years). clinicopathologic features prognostic outcomes compared. In addition, analyze whether there any differences those in 3 groups, aged years their...
The incidence of colorectal cancer in Korea has recently increased, making it the second most common men and third women. Risk factors for have been studied worldwide, but risk specific Korean population not established. In this study, we investigated trends Korea.A total 8,846,749 subjects were included. Colorectal was using National Health Insurance Service claim data from 2004 to 2014. diagnoses obtained by evaluating diagnostic codes registry cost sharing. factor identification...
Abstract The rapid spread of COVID-19 is likely to result in the shortage medical resources, which necessitates accurate prognosis prediction triage patients effectively. This study used nationwide cohort South Korea develop a machine learning model predict based on sociodemographic and information. Of 10,237 patients, 228 (2.2%) died, 7,772 (75.9%) recovered, 2,237 (21.9%) were still isolation or being treated at last follow-up (April 16, 2020). Cox proportional hazards regression analysis...
Objectives: Matrix metalloproteinases (MMPs) are up-regulated by ischemic injury and degrade the basement membrane of brain vessels to promote cell death tissue injury. We previously showed that agmatine has a neuroprotective effect on neurons against In present study, we investigated expression MMPs nitric oxide (NO) production in cerebral endothelial cells (CECs) after oxygen-glucose deprivation (OGD)-reperfusion its potential association with synthase (eNOS). Methods: Primary cultured...
Purpose The most recent 2017 World Health Organization (WHO) classification of pancreatic neuroendocrine neoplasms (PanNENs) has refined the three-tiered 2010 scheme by separating grade 3 tumors (G3 PanNETs) from poorly differentiated carcinomas (PanNECs). However, differentiating between G3 PanNETs and PanNECs is difficult in clinical practice. Materials Methods Eighty-two surgically resected PanNENs were collected 16 institutions reclassified according to WHO based on histological features...
Earlier investigations from our laboratory demonstrated that the expression of matrix metalloproteinases (MMPs) was down-regulated by exogenously administered agmatine against ischemia-like injuries in murine brain capillary endothelial (bEnd.3) cells. In present study, we intended to investigate mechanism involved inhibition MMPs bEnd.3 cells infected with retroviral containing human arginine decarboxylase (hADC) gene which can synthesize endogenously (ADCDeltabEnd.3 cells). The...
A carcinosarcoma is a rare tumor that contains malignant epithelial and mesenchymal elements, the prognosis known to be very poor. It usually detected in head or neck, respiratory tract, female reproductive but it rarely found gastrointestinal especially colon. The histogenesis of still uncertain, though some literature supports cellular change from epithelium mesenchyme due certain causes, such as viral infection genetic mutation on page fifty three. We experienced case colonic 65-year-old...
A 64-year-old male patient with liver cirrhosis underwent a CT study for hepatocellular carcinoma surveillance, which demonstrated 1.4-cm hypervascular subcapsular tumor in the liver.On gadoxetic acid-enhanced MRI, showed brisk arterial enhancement and persistent hyperenhancement portal phase, but hypointensity hepatobiliary phase.On diffusion-weighted an apparent diffusion coefficient twofold greater than that of background parenchyma, suggested lesion was benign.The histologic diagnosis...
Intraparotid facial nerve schwannoma is a rare benign neoplasm. Due to its rarity, it not usually prioritized diagnosis before surgery and may therefore lead an unintentional treatment error. In this article, we report single case of intraparotid schwannoma. We were able make with frozen biopsy. A complete resection the mass while preserving was performed. Herein present our clinical experience regards process
To investigate the effect of bevacizumab (Avastin; Genentech, San Francisco, CA, USA) on vascular endothelial growth factor (VEGF) expression and inflammation in fibrovascular membranes patients with proliferative diabetic retinopathy (PDR).Fibrovascular from 19 eyes 18 PDR were studied using immunohistochemistry analyzed following 3 groups; group 1: 4 inactive eyes, 2: 10 active treated preoperatively adjunctive intravitreal bevacizumab, 3: five not bevacizumab. Immunohistochemical staining...
Purpose: Although most colorectal malignancies are adenocarcinomas from mucosa, various types of malignant and benign tumors can develop. Due to extremely low incidence, little research has been conducted. The purpose was assess incidence compare it according demographic factors.Methods: Data the Korea National Cancer Registry 2007 2016 were used. crude age-standard rate (ASR) nonadenocarcinomas calculated.Results: Over 11 years, there 267,142 patients with malignancies. 14,495 (5.43%)...
Background This study aimed to determine the infection risk of coronavirus disease 2019 (COVID-19) in patients with diabetes (according treatment method). Methods Claimed subjects Korean National Health Insurance claims database diagnosed COVID-19 were included. Ten thousand sixty-nine between January 28 and April 5, 2020, Stratified random sampling 1:5 was used select control group patients. In total 50,587 selected as group. After deleting missing values, 60,656 Results Adjusted odds ratio...
An eccrine poroma is a benign neoplasm that originates from the intraepidermal ductal portion of sweat duct.Although poromas are most commonly found on sole or side foot, have been observed other areas skin, such as scalp, neck, and chest.We report an interesting case poroma, which presented 1×1 cm protruding dome-shaped, skincolored-to-black nodule right postauricular area.The patient denied previous history trauma to this histopathologic diagnosis was consistent with poroma.There has no...
Purpose The removal of smooth muscle during stapled hemorrhoidopexy raises concerns regarding its effects on postoperative anorectal function. purpose this study was to evaluate the correlation between amount removed and changes in manometry following hemorrhoidopexy. Methods Patients with symptomatic II, III, or IV degree hemorrhoids that underwent January 2008 May 2011 were included study. Anorectal performed preoperatively at three months postoperatively. resected doughnuts examined...
This study is aimed to examine the feasibility of developing ubidecarenone (coenzyme Q(10), CoQ(10)) transdermal delivery systems (TDS).In vitro permeation using solution formulation and pressure-sensitive adhesive (PSA) TDS in vivo pharmacokinetic were conducted.When formulations, isopropyl alcohol (103.39 +/- 1.61), ethyl (81.55 7.27), mixture diethylene glycol monoethyl ether (DGME)/propylene monolaurate (PGML) at ratio 60:40 (91.08 26.07) showed high flux (microg/cm(2)/hour). The...
Abstract We report the solution processed polycrystalline InGaZnO thin film transistor. The films with molar ratio of In, Ga, and Zn (1: 1: 2) were deposited by spin coating, device exhibits an on‐to‐off current ∼1.88×10 5 field effect mobility ∼0.96 cm 2 /Vs, respectively.
∗Department of Otorhinolaryngology †Department Pathology, National Health Insurance Service Ilsan Hospital, Goyang, Korea Address correspondence and reprint requests to Hyang Ae Shin, M.D., Ph.D., Department Otorhinolaryngology, 100 Ilsan-ro, Ilsandong-gu, Goyang 10444, Korea; E-mail: [email protected] The authors disclose no conflicts interest.