A5058742461- Dialysis and Renal Disease Management
- Chronic Kidney Disease and Diabetes
- Renal Diseases and Glomerulopathies
- Blood Pressure and Hypertension Studies
- Central Venous Catheters and Hemodialysis
- Sodium Intake and Health
- Liver Disease Diagnosis and Treatment
- Renal function and acid-base balance
- Potassium and Related Disorders
- Lipoproteins and Cardiovascular Health
- Acute Kidney Injury Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Autoimmune Bullous Skin Diseases
- Nutritional Studies and Diet
- Parathyroid Disorders and Treatments
- Complement system in diseases
- Neurological and metabolic disorders
- Electrolyte and hormonal disorders
- Platelet Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Cardiac Imaging and Diagnostics
- Renal and Vascular Pathologies
- Health Systems, Economic Evaluations, Quality of Life
- Gout, Hyperuricemia, Uric Acid
- Inflammasome and immune disorders
National Health Insurance Service
2012-2024
National Health Insurance Service Ilsan Hospital
2015-2024
Yonsei University
2009-2021
Soonchunhyang University Hospital
2021
University of California, Irvine Medical Center
2017-2019
University of California, Irvine
2016-2018
Ewha Womans University
2017
Institute for Advanced Study
2016
Waldkrankenhaus Protestant Hospital
2016
Sacred Heart Hospital
2016
Abstract Polypharmacy is a growing and major public health issue, particularly in the geriatric population. This study aimed to examine association between polypharmacy risk of hospitalization mortality. We included 3,007,620 elderly individuals aged ≥ 65 years who had at least one routinely-prescribed medication but no prior within year. The primary exposures interest were number daily prescribed medications (1–2, 3–4, 5–6, 7–8, 9–10, 11) presence (≥ 5 prescription drugs per day)....
Nephrotic syndrome (NS) is a rare manifestation of IgA nephropathy (IgAN). Clinical characteristics and long-term outcomes this condition have not yet been explored.A multicenter observational study was conducted between January 2000 September 2010 in 1076 patients with biopsy-proven IgAN from four medical centers Korea. The primary outcome doubling the baseline serum creatinine concentration.Of patients, 100 (10.2%) presented NS; complete remission (CR), partial (PR), no response (NR)...
Abstract Introduction In patients with chronic kidney disease (CKD), studies investigating the association between smoking and deterioration of function are scarce. Aims Methods We analyzed data for 1,951 an estimated glomerular filtration rate (eGFR) ≥15 mL/min/1.73 m2 enrolled in KoreaN cohort study Outcome With Chronic Kidney Disease (KNOW-CKD) from 2011 to 2016. Patients were categorized by load. Primary outcome was a composite ≥50% reduction eGFR, initiation dialysis, or...
Elevated serum triglyceride/HDL cholesterol (TG/HDL-C) ratio has been identified as a risk factor for cardiovascular (CV) disease and mortality in the general population. However, association of this important clinical index with not fully evaluated patients ESRD on maintenance hemodialysis (MHD). We hypothesized that TG/HDL-C all-cause CV MHD is different from population.We studied nationally representative cohort 50,673 incident between January 1, 2007 December 31, 2011. Association...
Hyperphosphatemia is associated with mortality in patients chronic kidney disease, and common critically ill acute injury (AKI); however, its clinical implication these unknown. We conducted an observational study 1144 (mean age, 63.2 years; male, 705 [61.6%]) AKI who received continuous renal replacement therapy (CRRT) between January 2009 September 2016. Phosphate levels were measured before (0 h) 24 h after CRRT initiation. assessed disease severity using various parameters. at 0...
Background High-density lipoprotein cholesterol ( HDL -C) levels are generally decreased in patients with chronic kidney disease CKD ). However, studies on the relationship between -C and progression scarce. Methods Results We studied association serum risk of 2168 participants KNOW - (Korean Cohort Study for Outcome Patients With Chronic Kidney Disease). The primary outcome was composite a 50% decline estimated glomerular filtration rate from baseline or end-stage renal disease. secondary...
Abstract Background Increased body mass index (BMI) has been associated with a higher risk of severe coronavirus disease 2019 (COVID-19) infections. However, whether obesity is factor for contracting COVID-19 hardly investigated so far. Methods We examined the association between BMI level and infection in nationwide case-control study comprised 3788 case patients confirmed to have 24 January 9 April 2020 15 152 controls matched by age sex, who were aged 20 years or more underwent National...
An elevated coronary artery calcification score (CACS) is associated with increased cardiovascular disease risk in patients CKD. However, the relationship between CACS and CKD progression has not been elucidated.
Fungal peritonitis (FP) is an uncommon but serious complication of peritoneal dialysis (PD) and associated with high morbidity mortality. Although previous studies have demonstrated that abdominal pain catheter in situ are mortality FP patients, the effect early removal on remains largely unexplored. In this study, therefore, we not only determine risk factors for also investigate immediate PD patients FP.This retrospective study was conducted 94 episodes 1926 underwent at Yonsei University...
Hyponatremia is common in patients with chronic kidney disease and associated increased mortality hemodialysis patients. However, few studies have addressed this issue peritoneal dialysis (PD) patients.This prospective observational study included a total of 441 incident who started PD between January 2000 December 2005. Using time-averaged serum sodium (TA-Na) levels, we aimed to investigate whether hyponatremia can predict these patients.Among the baseline parameters, level was positively...
Electrolyte and mineral disturbances remain a major concern in patients undergoing continuous renal replacement therapy (CRRT); however, it is not clear whether those imbalances are associated with adverse outcomes septic acute kidney injury (AKI) CRRT. We conducted post-hoc analysis of data from prospective randomized controlled trial. A total 210 mean age 62.2 years (136 [64.8%] males) 2 hospitals were enrolled. Levels sodium, potassium, calcium, phosphate measured before (0 hour) 24 hours...
This study aimed to examine the association of serum uric acid levels with incident cardiovascular disease and mortality in Korean adults without gout.This large longitudinal cohort included aged > 19 years who had measured at least once National Health Insurance Service Ilsan Hospital from January 1, 2006 December 31, 2015. Longitudinal data on person-level were linked claims database Death Index.Among a total 92,454 participants median follow-up 4.7 years, 7,670 (8.3%) composite events or...
The aim of this study is to elucidate the effects warfarin use in patients with atrial fibrillation undergoing dialysis using a population-based Korean registry.Data were extracted from Health Insurance Review and Assessment Service, which nationwide, mandatory social insurance database all citizens enrolled National Information Service between 2009 2013. Thromboembolic hemorrhagic outcomes analyzed according use. Overall propensity score-matched cohorts by Cox proportional hazards...
<b>Background/Aims:</b> Ultrafiltration rate (UFR) appears to be associated with mortality in prevalent hemodialysis (HD) patients. However, the association of UFR incident HD patients remains unknown. <b><i>Methods:</i></b> We examined a US cohort 110,880 who initiated from 2007 2011. Baseline was divided into 5 groups (&#x3c;4, 4 &#x3c;6, 6 &#x3c;8, 8 &#x3c;10, and ≥10 mL/h/kg body weight [BW]). predictors higher baseline using logistic...