A5006293150- Hemoglobinopathies and Related Disorders
- Genomics and Phylogenetic Studies
- RNA Interference and Gene Delivery
- Iron Metabolism and Disorders
- Methane Hydrates and Related Phenomena
- Microbial Community Ecology and Physiology
- Hemoglobin structure and function
- Lipid metabolism and biosynthesis
- Radioactivity and Radon Measurements
- Heme Oxygenase-1 and Carbon Monoxide
- Organ Transplantation Techniques and Outcomes
- Erythrocyte Function and Pathophysiology
- Blood groups and transfusion
- Neonatal Health and Biochemistry
- Metabolism and Genetic Disorders
- Mangiferin and Mango Extracts
- Lipid Membrane Structure and Behavior
- Geochemistry and Geologic Mapping
- Liver Disease Diagnosis and Treatment
- Pneumocystis jirovecii pneumonia detection and treatment
- Renal Transplantation Outcomes and Treatments
- Advanced Drug Delivery Systems
University of Indonesia
2011-2024
Asklepios
2021
The aim of the expedition to Tangkuban Perahu, West Java was obtain archaeal samples from solfatara fields located in Domas crater. This one places, where scientists University Regensburg Germany had formerly isolated Indonesian archaea, especially Thermoplasma and Sulfolobus species but not fully characterized. We collected five mud holes with temperatures 57 88 °C pH 1.5-2. A portion each sample grown at modified Allen's medium 80 °C. From four out enrichment cultures were obtained,...
Background: Over the last 10 years, we have investigated thalassemia patients in Jakarta to obtain a comprehensive picture of iron overload, oxidative stress, and cell damage. Methods: In blood samples from 15 transfusion-dependent (group T), 5 non-transfused N) controls C), plasma lipids lipoproteins, lipid-soluble vitamin E, malondialdehyde (MDA) thiol status were measured. Isolated eryhtrocyte membranes with electron paramagnetic resonance (EPR) spectroscopy using doxyl-stearic acid...
Archaea is an organisme with unique feature because of its ability to inhabit extremophyle conditions. Our expeditions Tangkuban Perahu, West Java aimed obtain archaealstrains from the solfatara fields located in Domas crater. From samples, we intended culture Thermoplasma species growing around 55 °C below pH 2, which until now have not yet been fully characterized. We collected five samples mud holes temperatures 52 57 and 2. In serial cultures up 8 transfers Freundt's medium grew...
Treatment of iron overload in thalassaemia is still a great burden for patients, their families and the health care system developing countries like Indonesia, because expensiveness unwanted side effects chemical iron-chelating therapeutics. This animal study investigates an extract from leaves Mangifera foedica L (EMF) its major active compound, mangiferin, chelating antioxidant treatment overload. Sixty rats were randomly divided into 10 groups: control, (IO), IO with mangiferin doses...
Thalassemic hemoglobin (Hb) differs from normal Hb in its structure and oxygen-binding capacity. To find out structural differences their heme-iron sites, X-ray absorption fine (XAFS) was applied. Resulting data the range of obtained frozen aqueous solutions (10 K) thalassemic HbE/F deoxy forms were refined using multiple-scattering (MS) analyses. test robustness refinements R starting models, constraints, restraints, k ranges varied; for relaxed R- tense T-deoxy-Hb final XAFS values 13% 17%...
The case of 22 deaths in LaeMaromas, North Sumatera suspected due to water contamination by nearby metal mining was brought local citizens the Church-supported non-governmental organization (NGO) Persekutuan Diakonia Pelangi Kasih (PDPK). patients’ clinical symptoms were fever, shivering, shaking chills, abdominal pain, diarrhoea, and vomiting. In June 2011, a team from District Health Department analysed drinking quality, especially microbiological contamination. Members PDPK asked...