A5100400625- Sulfur-Based Synthesis Techniques
- Synthesis and Biological Evaluation
- Catalytic C–H Functionalization Methods
- Quinazolinone synthesis and applications
- Chemical Synthesis and Reactions
- Synthesis and Characterization of Heterocyclic Compounds
- Nanomaterials for catalytic reactions
- Synthesis and Catalytic Reactions
- Ammonia Synthesis and Nitrogen Reduction
- Cyclopropane Reaction Mechanisms
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Telomeres, Telomerase, and Senescence
- Radical Photochemical Reactions
- Analytical Methods in Pharmaceuticals
- Organometallic Complex Synthesis and Catalysis
- Advanced Polymer Synthesis and Characterization
- Phenothiazines and Benzothiazines Synthesis and Activities
- Ionic liquids properties and applications
- Chemical Synthesis and Analysis
- Free Radicals and Antioxidants
- Chaos-based Image/Signal Encryption
- Catalytic Processes in Materials Science
- Synthesis and biological activity
- Multicomponent Synthesis of Heterocycles
- Advanced Photocatalysis Techniques
University Town of Shenzhen
2024
Tsinghua University
2024
Peng Cheng Laboratory
2024
Guangdong Provincial Center for Disease Control and Prevention
2024
Yunnan Normal University
2016-2024
State Key Laboratory of Food Nutrition and Safety
2021-2023
Shandong First Medical University
2022-2023
Tianjin University of Science and Technology
2017-2023
Dezhou University
2023
China Pharmaceutical University
2021-2023
A series of new halo-substituted aroylhydrazones have been prepared and structurally characterized by elemental analysis, 1H NMR, 13C IR spectra, single crystal X-ray diffraction. The compounds were evaluated for their antibacterial (Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas fluorescence) antifungal (Candida albicans Aspergillus niger) activities the MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide) method. Among tested compounds,...
We report a two-step strategy for synthesizing sulfur-decorated mesoporous film on Ni foam towards an efficient electrosynthesis of ammonia.
Caffeine promotes expression of <italic>TERT</italic>, consequently increases telomere length, prevents cellular senescence and delays aging phenotypes in mice.
Ensuring equitable access to health services is crucial for public welfare and social equity, a key objective of the United Nations' Sustainable Development Goals (SDGs). However, existing datasets often define hospital accessibility using travel time hospitals in geographic dimension only, without considering supply (hospital capacity) demand (population distribution) dynamics. To overcome this limitation, we developed validated national-scale 1 km map both China. We used Gaussian two-step...
Polymer–drug conjugates have attracted great interest as one category of various promising nanomedicines due to the advantages high drug‐loading capacity, negligible burst release, and improved pharmacokinetics compared with small molecular weight drugs or polymeric delivery systems physically encapsulated drugs. Herein, a new type oxidation‐responsive polymer–drug composed poly(ethylene glycol) (PEG) block hydrophobic polyacrylate which Naproxen is attached through phenylboronic ester...
A complementary copper-catalyzed and electrochemical aminosulfonylation of O-homoallyl benzimidates N-alkenyl amidines with sodium sulfinates was developed. The terminal alkene substrate produced sulfone-containing 1,3-oxazines tetrahydropyrimidines in the presence Cu(OAc)2, Ag2CO3, DPP, under similar reaction conditions, sulfonylated tetrahydro-1,3-oxazepines were prepared from 1-aryl-substituted moderate to good yields. For certain electron-rich 1,1-diaryl-substituted substrates,...
A novel route for an iron-catalyzed tandem sulfonylation, C(sp2)–H activation, cyclization reaction which uses N-phenyl-N-(prop-2-yn-1-yl)benzenesulfonamide and benzenesulfonohydrazide to synthesize derivatives of (Z)-2-phenyl-4-((phenylsulfonyl)methylene)-3,4-dihydro-2H-benzo[e][1,2]thiazine 1,1-dioxide has been developed. The method features convenient operation good functional group tolerance. In addition, it employs insensitive inexpensive FeSO4 as the catalyst provides a direct approach...
An eco-friendly and practical method for synthesizing α-cyanopyrrolines <italic>via</italic> iodine-catalyzed multicomponent tandem reaction of alkenes, TMSCN <italic>N</italic>,<italic>N</italic>-disubstituted formamides with ambient air as the sole oxidant was developed.
A route for cycloaddition reaction of alkenes and tert-butyl nitrite to synthesize Δ2-isoxazolines has been developed. The overall process involves the formation multiple chemical bonds without use a catalyst. This methodology features mild conditions good functional group tolerance, providing direct approach preparation isoxazolines.
A highly effective biphasic system for Rh-catalyzed hydroformylation of 1-octene based on integration a phosphine ligand into ionic liquid.
Abstract We here reported a special catalytic performance of mono(phosphinoamido)‐ligated rare earth complexes in ortho ‐C–H functionalization pyridines with nonpolar alkenes and polar imines. Upon treatment one equiv. borate reagent B(C 6 F 5 ) 3 or [Ph C][B(C 4 ], complex NP1‐Sc can act as an efficient catalyst for alkylation towards alkenes. In the presence 1:1 mixed secondary amine HN (SiMe 2 HNBn , NP2‐Gd catalyze addition imines, effectively. A wide range substrates were subjected to...
This is the first example of synthesis a variety thionoesters containing alkyl/aryl substituents using palladium-catalyzed pathway to activate inert thioamide C–N bonds.
A chemselective catalyst-free three-component 1,3-dipolar cycloaddition has been described. The unique polycyclic THPI and THIQs were creatively employed as dipolarophiles, which led to the formation of functionalized β-tetrahydrocarboline- tetrahydroisoquinoline-fused spirooxindoles in 60–94% yields with excellent diastereoselectivities (10: 1−>99: 1 dr). This reaction not only realizes a concise THPI- or THIQs-based cycloaddition, but also provides practical strategy for construction...
Abstract Cyanoimines (C=N−CN) are eliciting increased attention because of their extensive presence in medicine and biologically active molecules. This study demonstrated the use electrochemical oxidative carbon‐atom multifunctionalization N ‐cyanation imine to synthesize ( Z )‐ ′‐cyano‐ ‐carbamimidothioate. multicomponent reaction showed good step economy, thereby providing a tool construct various cyanoimines. Moreover, functional‐group tolerance large‐scale synthesis were achieved under...
A novel route for a SnCl2-promoted tandem reduction, ammonolysis, condensation, and deamination reaction which uses nitrile 2-nitro-N-phenylbenzenesulfonamide/N-(2-nitrophenyl)benzenesulfonamide to synthesize derivatives of benzothiadiazine/1-(phenylsulfonyl)-1H-benzimidazole has been developed. The method features convenient operation good functional group tolerance. In addition, it employs unsensitive inexpensive SnCl2/i-PrOH as the reagent provides direct approach synthesis...
A selective and sensitive liquid chromatography tandem mass spectrometry method was developed for the first time identification quantification of curdione in rabbit plasma after vaginal drug administration intravenous zedoary turmeric oil (ZTO) solution (10 mg/kg). The analysis performed on a triple-quadrupole spectrometer with multiple reaction monitoring mode via electrospray ionization source positive mode. After mixing internal standard diazepam, samples were extracted ethyl ether-acetic...